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Gadol effervescence tablet

A Rhodiola rosea and effervescent tablet technology, applied in the field of effervescent tablets, can solve the problems of poor absorption, low bioavailability, and slow disintegration, and achieve the effects of fast absorption, high bioavailability, and rapid disintegration

Inactive Publication Date: 2007-07-11
天津市天骄制药有限公司
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

[0003] Traditional oral solid rhodiola preparations such as ordinary tablets and capsules have disadvantages such as slow disintegration (needing 30 minutes or more), poor absorption, and low bioavailability

Method used

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  • Gadol effervescence tablet
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Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0073] Prescription: Rhodiola Rosea Extract 20g (2%)

[0074] Lactose 360g (36%)

[0075] Citric acid 300g (30%)

[0076] Apple Flavor 5ml

[0077] Sodium bicarbonate 320g (32%)

[0078] Process: pass the above-mentioned raw and auxiliary materials through an 80-mesh sieve, mix them evenly, and press them into tablets. (method 1)

Embodiment 2

[0080] Prescription: Rhodiola Rosea Extract 60g (6%)

[0081] Starch 400g (40%)

[0082] Fumaric acid 200g (21%)

[0083] Pineapple Flavor 10ml

[0084] Sodium bicarbonate 320g (32%)

[0085] Sodium carbonate 20g (2%)

[0086] 10% starch slurry 10ml

[0087] Process: Take the prescription amount of Rhodiola rosea extract, lactose, and citric acid, pass through an 80-mesh sieve and mix well, granulate with 10% starch slurry, dry the granules below 60°C, add the prescription amount of sodium bicarbonate and Magnesium stearate is mixed evenly and compressed into tablets. (method 2)

Embodiment 3

[0089] Prescription: Rhodiola Rosea Extract 100g (10%)

[0090] Protein sugar 10g (1%)

[0091] Micropowder silica gel 320g(32%)

[0092] Malic acid 260g (26%)

[0093] Sodium bicarbonate 290g (29%)

[0094] Magnesium Lauryl Sulfate 20g (2%)

[0095] 10% starch slurry 15ml

[0096] Process: Take prescription amount of Rhodiola rosea extract, citric acid, protein sugar and a part of lactose, pass through an 80-mesh sieve and mix evenly, granulate with 10% starch slurry, and dry the granules below 60°C; take prescription amount of bicarbonate Sodium and another part of lactose are passed through an 80-mesh sieve, mixed evenly, granulated with 10% starch slurry, and the granules are dried below 60°C; after granulation, magnesium stearate is added, mixed evenly, and tabletted. (method 2)

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Abstract

The invention relates to effervescent tablets with health care function which comprises the following constituents (by weight portions): rhodiola root extract 2-20%, edible acid 20-30%, edible alkali 25-35%, bulking agent 20-40%, binding agent 0-5%, flavoring agent 0-3%, lubricating agent 0-5%. The invention features in rapid absorption, high biological availability and sufficient curative effect.

Description

technical field [0001] The invention relates to an effervescent tablet with health care function, in particular to an effervescent tablet made of rhodiola rosea as the main raw material. Background technique [0002] With the rapid development of society, high-tech products such as computers, mobile phones, and microwave ovens are becoming more and more popular in millions of households. While we enjoy the convenience and happiness brought by high-tech, the radiation caused by mobile phones, computers, and microwave ovens Health problems are more and more people's attention and attention. At the same time, with the acceleration of the pace of life, people are under more and more pressure from work and family. A series of modern diseases (also known as sub-health) such as premature aging, cervical spondylosis, and insufficient blood supply to the brain caused by long-term hypoxia have become an impact. important factor in people's quality of life. Modern pharmacological stu...

Claims

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Application Information

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IPC IPC(8): A61K36/41A61K9/20A61K9/46A61K47/12A61K47/02A61P39/06A61P17/16A61K125/00
Inventor 田成旺凌景华于胜利尚虹
Owner 天津市天骄制药有限公司
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