The preparation method of rosmarinic acid
A technology of rosmarinic acid and ascorbic acid, applied in the separation/purification of carboxylic acid esters, organic chemistry, etc., can solve the problems of unsuitability for industrial production, residual organic solvents, and long consumption time, so as to reduce pressure and maintain stability , to avoid the effect of degradation
- Summary
- Abstract
- Description
- Claims
- Application Information
AI Technical Summary
Problems solved by technology
Method used
Image
Examples
Embodiment 1
[0044] Embodiment 1: the preparation of rosmarinic acid
[0045] Solvent extraction (dipping method): take Danshen and grind it through a No. 3 sieve, weigh 50Kg, add 50% ethanol according to 20 times its weight, soak at room temperature for 4 hours and stir properly, separate the extract, and the residue is 10 times the weight of the original medicinal material. Add 50% ethanol twice, soak at room temperature for 6 hours and stir properly, and separate the extract. Combine the two extracts, and remove solid impurities therein by filtration or centrifugation. Antioxidant sodium bisulfite is added into the filtrate, and the consumption of sodium bisulfite is 0.005% of the volume of the extract. After standing for 6 hours, the solution became turbid and precipitates gradually appeared, which were removed by filtration.
[0046] The above-mentioned filtrate is adjusted to about 20% alcohol concentration with water, and is added to a polyamide column, and the ratio of the sample...
Embodiment 2
[0048] Embodiment 2: the preparation of rosmarinic acid
[0049] It is basically the same as in Example 1, except that the medicinal material is perilla. Finally, 136 g of products with a rosmarinic acid content of 92.6% were obtained.
Embodiment 3
[0050] Embodiment 3: the preparation of rosmarinic acid
[0051] It is basically the same as in Example 1, except that the medicinal material is selected from Cinnamomum capitulata. Finally, 256 g of products with a rosmarinic acid content of 95.8% were obtained.
PUM
Abstract
Description
Claims
Application Information
- R&D Engineer
- R&D Manager
- IP Professional
- Industry Leading Data Capabilities
- Powerful AI technology
- Patent DNA Extraction
Browse by: Latest US Patents, China's latest patents, Technical Efficacy Thesaurus, Application Domain, Technology Topic, Popular Technical Reports.
© 2024 PatSnap. All rights reserved.Legal|Privacy policy|Modern Slavery Act Transparency Statement|Sitemap|About US| Contact US: help@patsnap.com