Compositions and methods for augmenting kidney function

a technology of kidney function and compositions, applied in the field of compositions and methods for augmenting kidney function, can solve the problems of negative impact of increased waste concentration on an individual's physiology, decrease in well-being, general malaise, etc., and achieve the effect of promoting a healthy intestinal microenvironment, eliminating nitrogenous waste products, and reducing the effect of physiological impa

Inactive Publication Date: 2005-04-07
KIBOW BIOTECH
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Benefits of technology

[0012] An object of the present invention is to provide a composition comprising prebiotic and probiotic components. This composition can be added to a food product, dietary supplement, medical food or pharmaceutical product which, upon ingestion, will promote a healthy intestinal microenvironment and assist in the elimination of nitrogenous waste products that can build up in concentration in the circulating blood. Increased concentrations of the wastes are known to exert a negative impact on an individual's physiology and contribute to a decreased sense of well-being and general malaise. Methods for reducing nitrogenous waste products using these products are also provided.

Problems solved by technology

Increased concentrations of the wastes are known to exert a negative impact on an individual's physiology and contribute to a decreased sense of well-being and general malaise.

Method used

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  • Compositions and methods for augmenting kidney function

Examples

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Effect test

example 1

Yogurt Food Product

[0047] A yogurt food product can be prepared from one gallon of commercially available whole, homogenized, pasteurized milk which is heated to boiling and quickly allowed to cool to approximately 45° C. To this is added approximately one ounce of yogurt starter culture containing lactic acid bacteria of the genus Lactobacillus, Streptococcus, Bacillus or Bifidobacteria. The mixture is mixed well and allowed to ferment at 37° C. for 10 to 12 hours. One or more prebiotics, whole fruit additives, flavoring, sweetening agents, binders, or other additives can be combined and added to the yogurt to obtain a product of desired consistency or to suit the palette of the prospective consumer. In one embodiment of the present invention, a food product comprises components to meet the special dietary needs of individuals with renal insufficiency.

example 2

Health Bar

[0048] Health bars can be prepared by combining various excipients, such as binders, additives, flavorings, colorants and the like, along with the prebiotic (e.g., Lactobacillus, Streptococcus, Bacillus or Bifidobacteria) and probiotic components, and mixing to a plastic mass consistency. The mass is then either extruded or molded to form “candy bar” shapes that are then dried or allowed to solidify to form the final product.

example 3

Medical Food

[0049] A medical food can be prepared by combining rolled oats, dehydrated apples, honey, inulin, carob flour, cinnamon, sugar, vanilla extract, and lyophilized cultures of L. acidophilus and or L. fermentum, a Bifidobacteria, and Streptococcus thermophilus (108-1010 cfu each). These ingredients are mixed in appropriate proportions with a prebiotic and formed into a rectangular bar approximately 12.5 to 15 centimeters in length, 3 to 4 centimeters in width and 1 centimeter in height and placed into a sterile vacuum oven for 12 to 24 hours to obtain an edible food product of the desired consistency.

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Abstract

The present invention provides a composition comprising prebiotic and probiotic components and is used to reduce elevated levels of nitrogenous waste products and to promote a healthy bowel microenvironment.

Description

[0001] This application is a continuation-in-part of U.S. Serial No. PCT / US02 / 07554 filed Mar. 13, 2002.FIELD OF THE INVENTION [0002] The present invention relates to compositions and methods which reduce the concentration of nitrogenous wastes. The compositions may be in the form of a food product, dietary supplement, medical food or drug. BACKGROUND OF THE INVENTION [0003] One of the main functions of the normal, healthy kidney, besides its regulatory, endocrine, and metabolic functions, is the disposal of waste products. Any impairment of excretory function can lead to the accumulation of a variety of nitrogenous waste products including, urea, creatinine and uric acid. High concentrations of waste products in the blood stream can exacerbate renal failure and promote kidney stones. Moreover, nitrogenous solutes in the circulating blood promote osmotic diffusion into the lumen because of the concentration gradient across the intestinal wall. This diffusion mechanism led to the con...

Claims

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Application Information

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Patent Type & Authority Applications(United States)
IPC IPC(8): A61K31/702A61K35/74A61K35/742A61K35/744A61K35/745A61K35/747A61K45/06
CPCA61K31/702A61K35/742A61K35/744A61K35/745A61K35/747A61K45/06A61K36/064A61K2300/00A61P13/12
Inventor RANGANATHAN, NATARAJAN
Owner KIBOW BIOTECH
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