Substituted pyrindinyl and pyrimidinyl derivatives as modulators of metabolism and the treatment of disorders related thereto

a technology of pyridinyl and pyridinyl derivatives, which is applied in the direction of biocide, drug composition, metabolic disorder, etc., can solve the problems of elevated blood glucose levels, serious health problems, and inability to move glucose into the cells of the body, so as to reduce the weight gain of the individual
US20070078150A1Inactive Publication Date: 2007-04-05ARENA PHARMA
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Patent Information

Authority / Receiving Office
US · United States
Patent Type
Applications(United States)
Current Assignee / Owner
ARENA PHARMA
Publication Date
2007-04-05
Estimated Expiration
Not applicable · inactive patent

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Abstract

The present invention relates to certain substituted pyridinyl and pyrimidinyl derivatives of Fomula (Ia) that are modulators of metabolism. Accordingly, compounds of the present invention are useful in the treatment of metabolic-related disorders and complications thereof, such as, diabetes and obesity.
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Description

RELATED APPLICATIONS

[0001] This application is a continuation of U.S. Ser. No. 11 / 482,777, filed Jul. 6, 2006, which is a continuation-in-part of U.S. Ser. No. 11 / 327,896, filed Jan. 9, 2006, which in turn claims the benefit of U.S. Ser. No. 60 / 642,840, filed Jan. 10, 2005, each of which is hereby incorporated by reference in its entirety.FIELD OF THE INVENTION

[0002] The present invention relates to certain substituted pyridinyl and pyrimidinyl derivatives that are modulators of glucose metabolism. Accordingly, compounds of the present invention are useful in the treatment of-metabolic-related disorders and complications thereof, such as, diabetes and obesity. BACKGROUND OF THE INVENTION

[0003] Diabetes mellitus is a serious disease afflicting over 100 million people worldwide. In the United States, there are more than 12 million diabetics, with 600,000 new cases diagnosed each year.

[0004] Diabetes mellitus is a diagnostic term for a group of disorders characterized by abnormal g...

Claims

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