Immune priming to accelerate/enhance immune response through administration of natural immune modulator

a technology of immune response and immune priming, which is applied in the field of immune system in animals and humans, can solve the problems of reducing productivity or compromising the safety or quality of the final product, adding significantly to poultry production costs, and losing many animal industries, etc., to achieve the effect of improving long-term treatment, cost-effectiveness, and convenient administration

Pending Publication Date: 2022-01-20
ZIVO BIOSCI
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  • Abstract
  • Description
  • Claims
  • Application Information

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Benefits of technology

[0010]The disclosed inventive concept provides an improved long-term treatment for a broad variety of diseases in both animals and humans. In animals, and particularly in poultry, the treatment method and composition ha

Problems solved by technology

Substantial economic losses in many animal industries, including the poultry industry, are most often the result of disease.
Diseases in flocks often result in reduced productivity or compromises in the safety or quality of the final product introduced into the food supply.
Prevention and treatment of poultry disease adds significantly to poultry production costs.
While this approach has shown some benefit, vaccines are known to suffer from very poor effectiveness in controlling the disease over time.
Experimentation has shown that a vaccine used in conjunction with a supplement such as a probiotic may improve outcome, but this approach adds to production cost.
Secondly, coccidiosis treatment today is accomplished conventionally through the use of antibiotics and ionophores, both of which

Method used

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  • Immune priming to accelerate/enhance immune response through administration of natural immune modulator
  • Immune priming to accelerate/enhance immune response through administration of natural immune modulator
  • Immune priming to accelerate/enhance immune response through administration of natural immune modulator

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example

[0055]According to the present, non-limiting example, the inventive compound is defined as the algal biomass as set forth above and related materials including algal supernatant and symbiont bacteria. The disclosed treatment compound was mixed with conventional feed to form a “feed mixture” at a fixed ratio at a ratio of 3.5 lbs. compound to one ton of feed. This ratio was maintained throughout the test period. The feed mixture was given to immune-naive birds on Day 1 as part of an ordinary feeding regimen and continued through the study period in an equal ratio. The “treatment compound” was represented by the algal biomass as set forth above and related materials including algal supernatant and symbiont bacteria. All ratios were maintained during the feeding period. The chickens were subjected to normal stress found in a minimum 25% of the US chicken population. This included being raised on built-up litter from previous flocks to replicate the typical stress experienced in the US ...

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Abstract

A method and compound for altering the status of both innate and adaptive immune pathways in both animals and humans are disclosed. The status alteration results in the immune response being primed whereby an accelerated and more robust response is generated when the animal or human is challenged by pathogens that lead to a wide range of disease states. The disclosed method utilizes a compound derived from a lipopolysaccharide (LPS) of gram-negative bacteria. The compound itself is a natural product with no observed adverse environmental impact. By priming the immune pathways according to the disclosed inventive concept, the severity of various disease states can be reduced, can be resolved more quickly, or can be avoided entirely.

Description

CROSS REFERENCE TO RELATED APPLICATION[0001]This application is a US. Non-provisional patent application of U.S. Provisional Patent Application No. 63 / 044,841, entitled “Immune Priming to Accelerate / Enhance Immune Response Through Administration of Natural Immune Modulator,” filed Jun. 26, 2020, which is herein incorporated by reference in its entirety for all purposes.TECHNICAL FIELD[0002]The present disclosed inventive concept relates to immune systems in animals and humans. More particularly, the disclosed inventive concept relates to a method and treatment using a compound that alters the status of both innate and adaptive immune pathways in both animals and humans. The status alteration results in the immune response being primed whereby an accelerated and more robust response is generated when the animal or human is challenged by pathogens that lead to a wide range of disease states.BACKGROUND OF THE INVENTION[0003]Substantial economic losses in many animal industries, includi...

Claims

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Application Information

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IPC IPC(8): A61K39/39A23K20/163A61K31/739
CPCA61K39/39A61K2039/55572A61K31/739A23K20/163A61K39/02A61K2039/552A61P37/02A23K50/75A23K20/158A61K35/74A23K10/16A61P33/02A61K39/0208
Inventor STEFFEK, AMY E.DAHL, ANDREW A.PFUND, WILLIAM P.
Owner ZIVO BIOSCI
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