The invention relates to a preparation method of a hydroxyapatite material doped with
fluorine and
potassium. The preparation method of the hydroxyapatite material doped with
fluorine and
potassium comprises the following steps: (1) uniformly mixing a Ca(NO3)2.4H2O
aqueous solution with a H3PO4
aqueous solution to obtain a
mixed solution, adjusting pH value of the
mixed solution till
sediment is generated, separating out the
sediment and washing the
sediment; (2)
drying the sediment obtained by the step (1), calcining the sediment at the temperature of 1300-1500 DEG C, and then quickly cooling the sediment to prepare alpha-
calcium phosphate powder; (3) dispersing the alpha-
calcium phosphate powder prepared by the step (2) in an alkaline solution containing K<+> and F<->, standing and aging at 80-160 DEG C for more than 12 hours, separating out
powder, and then washing and
drying to prepare the hydroxyapatite material doped with
fluorine and
potassium. By virtue of the preparation method, the problems that potassium salt is easily dissolved in water and not easily doped in the hydroxyapatite are solved; nanocrystals of the prepared hydroxyapatite material doped with fluorine and potassium are small in grain size and high in
crystal purity, so that the hydroxyapatite material doped with fluorine and potassium can be taken as a novel method with functions of treating hypersensitive
dentin, desensitizing and repairing and is long-term and efficient in treatment on hypersensitive
dentin.