The invention discloses zr-based amorphous-crystal multiphase material, which is composed of Zr 45-50at%, Cu 36-40at%, Al 8-10at%, rare earth elements RE 0.5-2at% and allowance refractory element M, wherein the rare earth elements RE is one of Y, Dy, Gd, Er or Lu, the refractory element M is one of Ta or W, a second phase which is rich Ta solid solution or W compound with high melting point is precipitated from the zr-based amorphous-crystal multiphase material which is prepared through a metal mould casting method. The volume fraction of amorphous alloy in the multiphase material of the invention is 90-99%, which occupies absolute advantage, the zr-based amorphous-crystal multiphase material breaks the defects of single block amorphous alloy that the plasticity is bad, the single block amorphous alloy is abruptly invalid and brittle failure, the thermal stability is bad, and the like, the fracture strength in 22DEG C is 1800-2100MPa, the yield strength is 1600-1900MPa, the plastic deformation reaches 4-15%, and the applicable range of the material in the engineering structure and biomedical materials fields is extended.