Looking for breakthrough ideas for innovation challenges? Try Patsnap Eureka!

Biodegradable medical magnesium alloy as well as preparation method thereof

A biomedical and magnesium alloy technology, applied in the field of biomedical materials, can solve the problems of magnesium matrix cytotoxicity and excessive corrosion, and achieve the effects of improving biocompatibility, increasing nucleation rate, and promoting nucleation.

Active Publication Date: 2014-01-22
ZHENGZHOU UNIV
View PDF2 Cites 22 Cited by
  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

[0004] The early clinical application of magnesium as a surgical material has confirmed the feasibility of magnesium for biomedical materials, but the magnesium matrix has problems such as cytotoxicity and excessive corrosion, which need further research and improvement

Method used

the structure of the environmentally friendly knitted fabric provided by the present invention; figure 2 Flow chart of the yarn wrapping machine for environmentally friendly knitted fabrics and storage devices; image 3 Is the parameter map of the yarn covering machine
View more

Image

Smart Image Click on the blue labels to locate them in the text.
Viewing Examples
Smart Image
  • Biodegradable medical magnesium alloy as well as preparation method thereof
  • Biodegradable medical magnesium alloy as well as preparation method thereof
  • Biodegradable medical magnesium alloy as well as preparation method thereof

Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0023] The first step preparation of cast Mg-1.0wt%Zn-0.2wt%Y-0.5wt%Nd-0.4wt%Zr magnesium alloy (target product)

[0024] Ⅰ Preparation

[0025] The raw materials needed for this experiment are:

[0026] High-purity magnesium ingot (purity ≥ 99.9%): 1326g

[0027] High-purity zinc ingot (purity ≥ 99.9%): 17.7g, in which the content of zinc is 1.25 times that of the obtained magnesium alloy (target product);

[0028] Mg-28.5wt%Y master alloy: 12.5g, wherein the content of Y is 1.4 times of its in the obtained magnesium alloy (target product);

[0029] Mg-30wt%Nd master alloy: 29.6g, wherein the content of Nd is 1.3 times of its in the obtained magnesium alloy (target product);

[0030] Mg-30wt%Zr master alloy: 47.2g, wherein the content of Zr is 2.5 times of its in gained magnesium alloy (target product);

[0031] In order to prevent the oxidation and combustion of magnesium alloys, a protective gas has been passed throughout the melting process. The protective gas used in ...

Embodiment 2

[0045] The first step preparation of cast Mg-2.0wt%Zn-0.5wt%Y-0.5wt%Nd-0.4wt%Zr magnesium alloy (target product)

[0046] Ⅰ Preparation

[0047] The raw materials needed for this experiment are:

[0048] High-purity magnesium ingot (purity ≥ 99.9%): 1360g

[0049] High-purity zinc ingot (purity ≥ 99.9%): 37.3g, in which the content of zinc is 1.25 times that of the obtained magnesium alloy (target product);

[0050] Mg-28.5wt%Y master alloy: 32.6g, wherein the content of Y is 1.25 times of its in the obtained magnesium alloy (target product);

[0051] Mg-30wt%Nd master alloy: 31g, wherein the content of Nd is 1.25 times of its in the obtained magnesium alloy (target product);

[0052] Mg-30wt%Zr master alloy: 49.6g, wherein the content of Zr is 2.5 times of its in the obtained magnesium alloy (target product);

[0053] In order to prevent the oxidation and combustion of magnesium alloys, a protective gas has been passed throughout the melting process. The protective gas us...

Embodiment 3

[0067] The first step preparation of cast Mg-3.0wt%Zn-1.5wt%Y-1.5wt%Nd-0.4wt%Zr magnesium alloy (target product)

[0068] Ⅰ Preparation

[0069] The raw materials needed for this experiment are:

[0070] High-purity magnesium ingot (purity ≥ 99.9%): 1280g

[0071] High-purity zinc ingot (purity ≥ 99.9%): 58.4g, in which the content of zinc is 1.25 times that of the obtained magnesium alloy (target product);

[0072] Mg-28.5wt%Y master alloy: 102.5g, wherein the content of Y is 1.25 times of its in the obtained magnesium alloy (target product);

[0073] Mg-30wt%Nd master alloy: 97.3g, wherein the content of Nd is 1.25 times of its in the obtained magnesium alloy (target product);

[0074] Mg-30 wt% Zr master alloy: 51.8g, wherein the content of Zr is 2.5 times of that in the obtained magnesium alloy (target product);

[0075] In order to prevent the oxidation and combustion of magnesium alloys, a protective gas has been passed throughout the melting process. The protective ...

the structure of the environmentally friendly knitted fabric provided by the present invention; figure 2 Flow chart of the yarn wrapping machine for environmentally friendly knitted fabrics and storage devices; image 3 Is the parameter map of the yarn covering machine
Login to View More

PUM

PropertyMeasurementUnit
Average grain sizeaaaaaaaaaa
Tensile strengthaaaaaaaaaa
Yield strengthaaaaaaaaaa
Login to View More

Abstract

The invention discloses a biodegradable medical magnesium alloy which consists of the following matters in percentage by weight: 1.0-3.0% of Zn, 0.20-1.50% of Y, 0.40-1.50% of Nd, 0.30-0.50% of Zr and the balance of Mg and inevitable impurity elements. Meanwhile, the invention discloses a preparation method of the alloy. The magnesium alloy is smelted to prepare common magnesium alloy. The use level of Zn, Y and Nd in furnace burden is 1.2-1.4 times the content of Zn, Y and Nd in the magnesium alloy, and the use level of Zr is 2-2.5 times the content of Zr in the magnesium alloy. According to the invention, the magnesium alloy overcomes the problems of cytotoxicity, excessively high corrosion rate and the like by adding rare earth elements Y, Nd and Zr into a magnesium-zinc alloy, and the potential difference with a matrix is reduced due to a lot of uniformly dispersed and distributed nano MgZn particle phases in the matrix by extrusion and processing, so that the corrosion resistance of the alloy is greatly improved, and the alloy has better mechanical properties.

Description

technical field [0001] The invention belongs to the field of biomedical materials, and in particular relates to a degradable biomedical magnesium alloy and a preparation method thereof. Background technique [0002] In recent years, with the improvement of people's living standards and changes in dietary structure, cardiovascular and cerebrovascular diseases caused by hyperlipidemia and hypertension have become one of the most important diseases that threaten human health. As early as the 20th century, minimally invasive interventional treatment of vascular diseases began to be applied, and was subsequently recognized as one of the most effective means of treating cardiovascular and cerebrovascular diseases; vascular stent implantation emerged as the times require, developed rapidly, and is being widely used in cardiovascular diseases. disease intervention. With the implantation of tiny stents, clinical conditions such as myocardial ischemia and coronary heart disease can b...

Claims

the structure of the environmentally friendly knitted fabric provided by the present invention; figure 2 Flow chart of the yarn wrapping machine for environmentally friendly knitted fabrics and storage devices; image 3 Is the parameter map of the yarn covering machine
Login to View More

Application Information

Patent Timeline
no application Login to View More
IPC IPC(8): C22C23/04C22C23/06C22C1/03C22F1/06
Inventor 关绍康季川祥朱世杰王利国马迅岳高超刘茜王剑锋
Owner ZHENGZHOU UNIV
Who we serve
  • R&D Engineer
  • R&D Manager
  • IP Professional
Why Patsnap Eureka
  • Industry Leading Data Capabilities
  • Powerful AI technology
  • Patent DNA Extraction
Social media
Patsnap Eureka Blog
Learn More
PatSnap group products

Browse by: Latest US Patents, China's latest patents, Technical Efficacy Thesaurus, Application Domain, Technology Topic, Popular Technical Reports.

© 2024 PatSnap. All rights reserved.Legal|Privacy policy|Modern Slavery Act Transparency Statement|Sitemap|About US| Contact US: help@patsnap.com