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Anti-infection hemodialysis tube

A hemodialysis tube and anti-infection technology, which is applied in the field of anti-infection hemodialysis tubes, can solve the problems of increasing the risk of microbial infection, reducing blood volume of patients, and large dialysis equipment, so as to reduce the probability of blood infection, prevent and treat related infections, The effect of increasing the dialysis area

Inactive Publication Date: 2018-03-02
成都测迪森生物科技有限公司
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

This process has the following problems: (1) The blood is separated from the body, which may cause a sharp decrease or increase in the blood volume of the patient, resulting in unstable blood pressure and even death; (2) The extracorporeal dialysis process usually only lasts for a few hours , unable to continuously, long-term, and stably perform hemodialysis for patients; (3) The extracorporeal dialysis equipment is huge and difficult to transport, and the patient needs to be transported to the dialysis room, or the huge extracorporeal dialysis machine is transported to the patient's bedside, which increases the difficulty of treatment
But this procedure has a new problem: directly placed in the blood vessel, increasing the risk of microbial infection

Method used

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Examples

Experimental program
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Effect test

Embodiment 2

[0044] This embodiment provides a polytetrafluoroethylene-polyurethane-nano-silver composite material and its preparation method. The polytetrafluoroethylene-polyurethane-nano-silver composite material has good biocompatibility and antibacterial properties, and it is used for hemodialysis The built-in dialysis tubing has a good application prospect. This polytetrafluoroethylene-polyurethane-nano-silver composite material is prepared through the following steps:

[0045] Step 1: Weigh 54g of polytetrafluoroethylene concentrated dispersion, 38g of diisocyanate, and 14g of polycaprolactone diol, stir and mix and heat to 80°C, add 0.08g of 1,4-butanediol and stannous octoate to it 0.06g, continue to stir and maintain the heating temperature for 3 hours, then raise the temperature to 90°C, and add 0.13g of trimethylolpropane monoallyl ether to continue the reaction for 3 hours, and the polytetrafluoroethylene-polyurethane composite material can be obtained;

[0046] Step 2: The po...

Embodiment 3

[0049] This embodiment provides a chitosan quaternary ammonium salt-polylactic acid composite membrane and a preparation method thereof. The chitosan quaternary ammonium salt-polylactic acid composite membrane is a positively charged hollow fiber membrane, which is used as a dialysis membrane for hemodialysis It has a good application prospect. This chitosan quaternary ammonium salt-polylactic acid composite film is prepared through the following steps:

[0050] Step 1: Take 28g of chitosan quaternary ammonium salt, 109g of polylactic acid, and 32g of polyethylene glycol, and dissolve them in 1L of dimethyl sulfoxide at 50°C to obtain a polylactic acid mixture; add methyl alcohol to the polylactic acid mixture Glycidyl acrylate 0.6g, add 0.001g of azobisisobutyronitrile after 30min of nitrogen gas, raise the temperature to 60°C and carry out free radical polymerization reaction under nitrogen protection for 20h to obtain chitosan mixed with glycidyl methacrylate Quaternary am...

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Abstract

The invention discloses an anti-infection hemodialysis tube, which relates to the field of medical equipment. The anti-infection hemodialysis tube of the present invention comprises a dialysis outer tube, a dialysis inner tube, and a dialysis membrane. Covering the outer wall of the dialysis inner tube; the dialysis inner tube has a U-shaped or V-shaped structure, and the openings are respectively a liquid inlet and a liquid outlet; the tubes of the dialysis outer tube and the dialysis inner tube are made of polyester Tetrafluoroethylene-polyurethane-nanosilver composite. In the present invention, the dialysis tube is directly placed in the blood vessel, without taking the blood out of the body and then performing hemodialysis through a machine. The nano-silver of the tube can effectively reduce the risk of infection in the hemodialysis process, and the chitosan quaternary ammonium salt in the dialysis membrane Make the composite membrane positively charged, form a positively charged barrier, effectively resist the bacteria in the dialysate from entering the blood, and further reduce the chance of blood infection during dialysis.

Description

technical field [0001] The invention relates to the field of medical equipment, in particular to an anti-infection hemodialysis tube. Background technique [0002] Hemodialysis is to use the principle that the solute flows from the side with high concentration to the side with low concentration, and introduce the two solutions of blood and dialysate into the dialyzer with hollow fiber semi-permeable membrane at the same time, so that the blood is located in the hollow fiber semi-permeable membrane. The dialysate is located on the other side of the hollow fiber semi-permeable membrane, so that the solutions on both sides of the membrane can remove medium and small molecule toxins in the human blood through diffusion and osmosis. At the same time, the electrolytes in the blood can also pass through Osmosis reaches balance, so as to achieve the purpose of blood purification. [0003] Hemodialysis is also a common method for the treatment of edematous diseases, acute and chroni...

Claims

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Application Information

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IPC IPC(8): A61M1/16A61M25/00A61L29/14A61L29/16A61L29/02A61L29/04A61L29/06A61L33/00B01D69/12B01D71/80
CPCA61M1/1625A61L29/02A61L29/041A61L29/043A61L29/06A61L29/14A61L29/16A61L33/0011A61L2300/104A61L2300/232A61L2300/236A61L2300/404A61L2300/42A61M25/0017A61M25/0026A61M25/0043A61M2025/0039A61M2210/12B01D69/12B01D71/80A61M2210/005C08L27/18C08L75/04C08L5/10C08L5/08
Inventor 郑浩
Owner 成都测迪森生物科技有限公司
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