3 results about "C h bond" patented technology

The invention relates to the field of synthesis of organic compounds, in particular to a double-C-N axial chiral heterocyclic compound and a preparation method thereof. The double-C-N axial chiral heterocyclic compound is a compound as shown in a formula I. The double-C-N axial chiral heterocyclic compound is prepared by taking quinoline-oriented benzamide as a substrate, taking large-steric-hindrance alkyne of an indole skeleton as a coupling reagent and taking cobalt salt as a catalyst through a cobalt-catalyzed carbon-hydrogen bond asymmetric activation reaction. And the method has the advantages of high yield, excellent enantioselectivity, simple and efficient reaction, mild conditions and avoidance of use of toxic chemical oxidants, and researches in the field of optical properties show that the system has potential application prospects.

The invention discloses a P450 hydroxylase mutant (named as P450AHS) and application of the P450 hydroxylase mutant in biosynthesis of axially chiral allenol compounds, and relates to the technical field of synthesis of the axially chiral allenol compounds. The P450 hydroxylase mutant has a function of biologically catalyzing allene carbon-hydrogen bond hydroxylation to synthesize an axially chiral allene alcohol compound, has high catalytic activity, is environment-friendly, is simple and convenient to operate, and has a wide application prospect.

This invention provides a class of organic light-emitting diode (OLED) host material derivatives and their synthesis methods. Specifically, the host material derivatives have the structure shown in Formula I, and the host material can be derivatized through a high-valent iodine reagent C-H bond functionalization reaction to obtain host material derivatives with different functional group modifications.