To efficiently search for mediators. [Solution] A
mediator search method is provided, which involves a
computer learning training data that associates experimental values of the electrical properties of a solution containing a
mediator and cells with the
mediator; estimating the electrical properties of each of a plurality of mediators not included in the training data based on the results of the learning; and adding the experimental values of the electrical properties of at least some of the plurality of mediators whose electrical properties have been estimated, along with the mediators themselves, to the training data, repeating this process until the experimental values of the electrical properties meet a criterion, thereby searching for a mediator whose experimental values meet the criterion.