43 results about "Ultra Low Temperature Freezer" patented technology

The invention discloses hydrophobic aerogel containing carboxyl nanocellulose and xanthan gum as well as a preparation method and application of the hydrophobic aerogel. The preparation method comprises the following steps: mixing cellulose and an acidic deep-eutectic solvent, performing water bath treatment, and stirring in distilled water through a wall breaking machine; mixing the nanocellulose suspension and the xanthan gum solution in equal mass, and uniformly stirring to obtain composite hydrogel; pre-freezing the composite hydrogel in an ultralow-temperature refrigerator, and performing vacuum freeze drying through a freeze dryer to obtain composite aerogel; spraying wax emulsion on the obtained composite aerogel, and drying to obtain the hydrophobic aerogel. The invention provides the hydrophobic aerogel containing the carboxyl nano cellulose and the xanthan gum, which is safe and environment-friendly, has good hydrophobic performance, adsorption performance and mechanical performance, can be directly used for food, and can be used for preparing an oil absorption pad and an oil absorption film.

1. The name of the design product: cryopreservation rack. 2. The use of the design product: the design product is used for the cryopreservation rack of the specimen in the ultra-low temperature refrigerator. 3. The design points of the design product: in shape. 4. The picture or photo that best indicates the design points: perspective view 1.

The invention discloses a preparation method of a blood coagulation factor quality control product. The preparation method comprises the following steps: treating mixed plasma of multiple persons by using a physical and chemical method; and mixing the multi-person mixed plasma with the factor diluent according to a certain proportion to prepare the blood coagulation routine item quality control product with different blood coagulation routine item contents at different concentration levels, subpackaging, and storing in an ultra-low temperature refrigerator at-80 DEG C to obtain the blood coagulation routine item quality control product. The blood coagulation routine item quality control product prepared by the invention is good in product uniformity, stability and frozen product remelting stability, can replace commercial products to be used for quality control of blood coagulation routine item detection, and is beneficial to reducing the detection cost and improving the blood coagulation routine item detection capability.

The invention discloses an ultra-low temperature refrigerator strong and weak current integrated frequency conversion controller which mainly comprises a power supply module, a temperature acquisition module, an MCU control chip, a display module, a power driving module and a motor. The controller provides stable power supply through the power supply module, and monitors the temperature in the box in real time through the temperature acquisition module. And the MCU control chip converts the temperature signal into a control signal through ADC (Analog to Digital Converter), and drives the power driving module to adjust the rotating speed of the motor, so that the dynamic adjustment of the refrigerating capacity is realized. And the display module communicates with the MCU and displays the temperature in the box in real time. Strong and weak current integration is combined with the frequency conversion control technology, the system cost is effectively reduced, meanwhile, accurate control and adjustment of the temperature in the refrigerator are ensured, and the working efficiency and reliability of the ultralow-temperature refrigerator are improved.

The invention relates to biological material engineering for cell culture, in particular to a method for enhancing freeze-drying stability of a porous microcarrier. Comprising the following steps: (1) standing a porous microcarrier which is fully swelled in water until the liquid level is about to be in contact with the porous microcarrier which is stood; (2) soaking the porous microcarrier obtained in the step (1) in an organic solvent for dehydration treatment; (3) transferring the dehydrated porous microcarrier in the container into a tray by using a pasteurization dropper, a pipettor or an electric pipettor, sealing the top of the tray, and pre-freezing in liquid nitrogen or an ultralow-temperature refrigerator; and (4) freeze-drying the pre-frozen porous microcarrier in a freeze drying box. The method provided by the invention can effectively solve the problems of shrinkage, collapse and structural damage of the porous microcarrier scaffold in the freeze drying process, and is short in drying period, low in energy consumption and suitable for large-scale production of porous microcarriers.

1. Name of the Design Product: Intelligent Environment Detector (OSD-IWIFI). 2. Use of the Design Product: This design is used for environmental monitoring in cell banks, cryogenic automated storage equipment, liquid nitrogen tanks, ultra-low temperature refrigerators, refrigerators, transfer tanks, thawing instruments, cold storage, etc. 3. Design Key Points of the Design Product: Lies in the shape. 4. Picture or Photograph that Best Illustrates the Design Key Points: Perspective View 1.

The invention provides a gonococcus transport and preservation method, which comprises the following steps: step 1, taking out one strain which is not freeze-dried from an ultralow-temperature refrigerator, placing the strain at room temperature for later use, after the strain is slightly dissolved, taking out a certain amount of bacterial liquid from a biosafety cabinet by using a pipettor, inoculating the bacterial liquid onto a pre-heated culture medium, marking lines in four regions, and then placing the culture medium in an incubator with a candle jar or a CO2 incubator at 36 DEG C for culturing for 36 hours; 2, picking pure bacteria in a biosafety cabinet by using a disposable inoculating loop, inoculating the pure bacteria to a pre-heated culture medium, and placing the culture medium in a 36-DEG C incubator with a candle jar or a CO2 incubator for culturing for 24 hours; and step 3, taking one sterile glass test tube, adding 1mL of sterilized normal saline, scraping bacterial lawn by using a disposable inoculating loop, grinding along the tube wall, putting on a vortex device, sufficiently and uniformly mixing, and adding into sterilized skim milk. The strain is subjected to freeze-drying preservation through a vacuum freeze-drying technology, so that energy expenditure for preservation of gonococcus is saved, and benefits are brought to distribution of national gonococcus interventricular quality assessment substances and transportation of national gonococcus drug-resistant monitoring point specimens.

The ultralow-temperature refrigerator comprises the pulse tube refrigerator, the thermosiphon and an ultralow-temperature refrigerator heat insulation shell, and the pulse tube refrigerator comprises an oil-free linear compressor, a connecting pipe, an after-stage cooler, a heat regenerator, a cold end heat exchanger, a pulse tube, a hot end heat exchanger, an inertia pipe and a pulse tube refrigerator gas reservoir. The thermosiphon comprises a thermosiphon air reservoir, a thermosiphon connecting pipe, a thermosiphon descending section and a thermosiphon ascending section. By utilizing the advantages of environmental protection, energy conservation and no horizontal vibration of the linear opposed pulse tube refrigerating machine, the problems of high energy consumption of a traditional cascade steam compression refrigerating system and unstable vibration operation of other novel refrigerating machines are solved. And the problem of low heat exchange efficiency caused by insufficient heat exchange is solved by utilizing the bent pipeline at the descending section of the thermosiphon. The problem that the ultralow-temperature refrigerator is unstable and unsafe when the refrigerating machine is shut down is solved by utilizing the advantage that the thermosiphon air reservoir is added to relieve overlarge pressure in the thermosiphon when the refrigerating machine is shut down.

The invention provides a mixed refrigerant as well as an additive, a preparation method and application thereof, and belongs to the technical field of refrigerants, the mixed refrigerant comprises the following components in parts by mass: a, 75 parts of combustible components including R290 and R1150; and b, a non-flammable component, the non-flammable component comprises R245fa, R23 and R728, and the non-flammable component is 210 to 265 parts by mass. According to the mixed refrigerant disclosed by the invention, combustible components and incombustible components are reasonably proportioned, and ethylene glycol, ethylene carbonate and propylene carbonate are added as additives, so that the performance of the refrigerant is remarkably improved. The refrigerant has the advantages of being excellent in environmental protection property, low in circulating energy consumption, high in low-temperature performance, good in temperature stability, high in recovery capacity and the like, is suitable for refrigeration equipment such as ultralow-temperature refrigerators, refrigeration houses and air conditioners, and has wide market prospects.

The utility model discloses a biological sample ultra-low temperature refrigerator capable of being placed in a classified mode, which comprises an ultra-low temperature refrigerator main body, the ultra-low temperature refrigerator main body comprises a main box body, a box door is installed on the front surface of the main box body through a hinge, and a sample placing frame is clamped in the main box body. A label placing transparent box is arranged on the surface of the sample placing rack; by designing a clamping assembly, an external thread ring can be rotated in an internal thread groove to fix an air bag body in a classified placement hole, the air bag body is filled with air, and a sample preservation tube penetrates through the air bag body until the sample preservation tube is embedded into the bottom end of the interior of the classified placement hole; and the air bag body deforms to clamp the sample storage tubes in the classified placement holes, so that the air bag body can deform to clamp and place the storage tubes with different sizes conveniently, the placement is more stable, and the classified placement stability of the ultralow-temperature refrigerator main body to the sample storage tubes with different sizes is improved.

The application discloses a kind of composite protein gels and preparation method thereof, its preparation method includes the following steps: with the blood collection tube with anticoagulant is collected blood;The above-mentioned blood is centrifuged at 300-700g centrifugal acceleration at room temperature 10-20min;After centrifugation, blood is transferred to biological safety cabinet, and the upper plasma layer is extracted, and then it is placed in-80 ℃ ultra-low temperature refrigerator and rapidly frozen, and the freezing time is 24-72h;Then, the frozen plasma is taken out, and freeze-drying treatment is carried out under the condition that the temperature is-55-65 ℃ and the pressure is 50-100Pa, and the freeze-dried plasma is prepared;Calcium chloride injection is added to the freeze-dried plasma at a volume ratio of 1:0.5-2, then reacted in a water bath at 60-90 ℃ for 5-15min, and removed to prepare.The protein gel can effectively solve the problem of easy skin stiffening, collapse, high in vivo absorption rate and poor filler stability caused by hyaluronic acid and autologous fat.

The utility model discloses a cell cryopreservation box which comprises a cover body and a box body matched with the cover body, two sides of the outer portion of the cover body are matched with two sides of the outer portion of the upper end of the box body to form a first sleeving device used for enabling the cover body to be attached to the box body in a sealed mode, two sides of the outer portion of the lower end of the box body are respectively provided with a second sleeving device, and a cryopreservation carrier is arranged inside the upper end of the box body. A cold gathering cavity is formed in the lower end of the box body and used in cooperation with an air inlet, an air inlet channel and an air inlet cap to adjust in-out and sealing of cold air in the cold gathering cavity, a card cavity is formed in the surface of the side, perpendicular to the first sleeving device, of the box body, and recording paper containing cryopreserved cell information can be inserted into the card cavity. When a large number of cells are cryopreserved, the second sleeving devices and the first lock catch grooves of the multiple box bodies can be used in a matched mode, multiple cryopreservation boxes are used in an overlapped mode, the space in the ultralow-temperature refrigerator is effectively saved, and the probability that a single cryopreservation box is forgotten is reduced.

A lily pollen dry storage box belongs to the field of agricultural and horticultural technology. The box comprises a C layer, a detachable A layer and / or a B layer arranged on the C layer, and after combination, a two-layer or three-layer storage box body is formed. The A layer and the B layer are both provided with a baffle with a plurality of through holes at the bottom. The A layer is a closed space with a seal, and the bottom is provided with a baffle I with a plurality of through holes I. A drying agent is arranged in the A layer. The B layer is an open box body, and the bottom is provided with a baffle II with a plurality of through holes II for containing fresh medicinal herbs. The C layer is an open box body for containing dried pollen. The bottom of the A layer and the B layer is provided with a detachable sealing connection structure matched with the top of the C layer. The top of the B layer and the top of the C layer have the same structure. Different varieties of lily pollen are separately collected in the plastic box, which is convenient for pollen classification and drying, and can be stored in a 4℃, -18℃ and ultra-low temperature refrigerator for a long time, prolonging the activity of the pollen, and having good airtightness, moisture resistance, spilling resistance, drop resistance and information searching convenience.

The invention relates to the technical field of ultralow-temperature refrigeration equipment, and discloses a refrigeration system. The refrigeration system comprises a refrigerator, a gravity heat pipe system, an air return pipe and a vibration reduction assembly. The refrigerator comprises a cold end; the gravity assisted heat pipe system is communicated with the cold end of the refrigerating machine, the gravity assisted heat pipe system comprises multiple paths of heat pipes arranged on the top and the peripheral side of the inner container, and a working medium collecting area is formed at the bottom of the multiple paths of heat pipes; the inflow end of the air return pipe is communicated with the working medium collecting area; the vibration reduction assembly comprises a first vibration reduction pipe and a second vibration reduction pipe, the first vibration reduction pipe is communicated between the inflow end of the gravity heat pipe system and the cold end of the refrigerator, and the second vibration reduction pipe is communicated between the outflow end of the air return pipe and the cold end of the refrigerator. By means of the arrangement, stable distribution of liquid films on the inner walls of the heat pipes can be guaranteed, meanwhile, it is avoided that backflow of heat exchange working media is blocked due to the fact that the heat pipes have reverse slopes or flat sections, and then the temperature control precision of the ultralow-temperature refrigerator is guaranteed. Meanwhile, the invention further discloses the ultralow-temperature refrigerator.

The invention discloses a calibration method for cryopreservation frame box body taking. The calibration method comprises the steps that S1, an infrared distance meter is correspondingly installed on a mechanical arm of an ultralow-temperature refrigerator; s2, in the designated area, a mechanical arm is moved to the corresponding cryopreservation frame box storing and taking position recorded historically, and the mechanical arm is controlled to move in the vertical direction and the horizontal direction of the irradiation vertical plane of the infrared distance meter; s3, in the moving process of the mechanical arm, the infrared distance measuring instrument synchronously collects infrared distance measuring results, and two sets of distance measuring fluctuations of the two sets of cryopreservation frame box bodies in the vertical direction are obtained correspondingly; and S4, the coordinate height and the translation amount position of the mechanical arm are recorded, and the corresponding box body taking position of the mechanical arm is obtained through calculation and used for controlling the mechanical arm to accurately take the box body. According to the method, the sample box storage positions on the cryopreservation frame are subjected to distance measurement calibration through laser, the sample calibration positions can be determined based on distance measurement data fluctuation, accurate positioning and taking of cryopreservation frame box bodies are achieved, and the dislocation taking influence caused by deformation in the ultralow-temperature environment is avoided.

The ultra-low temperature refrigerator convenient to classify comprises a refrigerator body, three storage frames are fixedly connected in the refrigerator body, two partition plates are fixedly connected in the refrigerator body, long grooves are formed in the upper sides of the side faces of the two partition plates, and the storage frames are fixedly connected in the long grooves. Two long grooves are formed in the top of the refrigerator body, adjusting plates are slidably connected to the front sides and the rear sides of the interiors of the two long grooves correspondingly, two sliding grooves are formed in the front side and the rear side of the top of the refrigerator body correspondingly, sealing plates are slidably connected to the interiors of the four sliding grooves in which every two sliding grooves form a group, and vertical rods of the E-shaped rods move out of the adjusting grooves by moving the two E-shaped rods downwards to extrude the two first compression springs. When the medicine storage box is used, fixation of the E-shaped plate is removed, the E-shaped plate slides to a proper position in the long groove, meanwhile, the vertical rod of the E-shaped rod moves into the proper adjusting groove, the space of the storage box is divided, more and larger medicines can be placed in the storage box, and the possibility of damage and deformation of the medicines is reduced.

The invention discloses a clinical test digital intelligent mobile laboratory which comprises a chassis and a compartment. Front wheels and rear wheels are arranged on the chassis, a cab is arranged at the front end of the chassis, and a driving device for driving the front wheels to rotate is installed at the front end of the chassis. The compartment is arranged on the chassis, three partition plates are arranged in the compartment and divide the compartment into a power supply area, a sample storage area, a medicine intravenous dispensing area and a pharmacy area, and side doors are arranged on the two partition plates close to the tail of the compartment. The power supply area is located on the front portion of the compartment and internally provided with a mute generator. The pharmacy area is positioned at the tail part of the carriage; a medical low-temperature box and a medical refrigerator are arranged in the pharmacy area; an ultralow-temperature refrigerator and a centrifugal machine are arranged in the sample storage area; a biological safety cabinet is arranged in the medicine intravenous distribution area; two cabin doors are arranged on the side face of the compartment, one cabin door is used for entering and exiting the power supply area, the other cabin door is used for entering and exiting the sample storage area or the medicine intravenous dispensing area, and a hinged door is arranged at the tail of the compartment. According to the invention, a mobile laboratory is formed, and the efficiency of clinical tests is improved.

The energy-saving ultralow-temperature refrigerator comprises an ultralow-temperature refrigerator body and an inner box, the inner box is placed in the ultralow-temperature refrigerator body, a storage cavity of a cylindrical structure is formed in the inner box, a taking and placing opening is formed in the side face, facing an opening of the ultralow-temperature refrigerator body, of the inner box, and a plurality of panels are installed in the inner box. A plurality of mounting cavities are formed between the panels, circular grooves are formed in the top surfaces of the panels, rotating plates are movably mounted in the circular grooves, a plurality of containing boxes are arranged in the mounting cavities in an annular structure, and the lower ends of the containing boxes are slidably connected with the rotating plates. The storage box is simple in structure, the inner box and the panel are arranged, stored articles can be separated in a layered mode, deep articles can be rotated to the front in a rotating mode, after the corresponding containing boxes are pulled out, the remaining containing boxes on the same layer are still in a sealed state, cold air exposure is greatly reduced, and the energy-saving effect is achieved.

The invention provides a step-by-step foaming method for an ultralow-temperature refrigerator based on a low-thermal-conductivity heat insulation plate frame, which comprises the following steps of: (1) preparing a heat insulation frame matched with an inner container by adopting a low-thermal-conductivity material, and enclosing and sealing a foaming space through a positioning structure to ensure that an evaporator is completely accommodated in the frame; (2) after the heat insulation frame is fixed, an LBA foaming material is injected into the frame for foaming, and a primary foaming layer is formed; and (3) sleeving a heat exchanger on the outer side of the heat insulation frame, integrally putting the heat insulation frame into a mold, and injecting a secondary foaming material containing a cross-linking agent into a gap outside the frame for foaming to form a secondary foaming layer. According to the invention, the peripheral space of the evaporator is precisely limited by the low-thermal-conductivity heat insulation plate frame, and a segmented process of primary foaming inside the frame and secondary foaming outside the frame is matched, so that the problems of obvious heat bridge in an evaporator area, non-uniform density of a foaming layer, poor foaming stability of pure LBA and the like in a traditional foaming process are solved; finally, the aims of improving the heat preservation performance of the ultralow-temperature refrigerator, reducing energy consumption, being stable in structure and environment-friendly and controllable in foaming are achieved.

The invention discloses an intelligent early warning system convenient for sample preservation, and relates to the technical field of sample preservation. Comprising an ultra-low temperature refrigerator body, the ultra-low temperature refrigerator body comprises a compressor and a refrigerator door, a plurality of storage plates are fixedly installed in the ultra-low temperature refrigerator body, a plurality of sample cells are fixedly arranged between every two storage plates, sensors are fixedly arranged on the surfaces of the storage plates, and the sensors are electrically connected with a controller. The controller is electrically connected with the ultralow-temperature refrigerator; in the normal operation process of the ultralow-temperature refrigerator, the temperature in the ultralow-temperature refrigerator is monitored in real time through the sensor, the monitored temperature is transmitted to the controller through the sensor, the controller sends an instruction to control starting and stopping of a compressor of the ultralow-temperature refrigerator, and therefore it is guaranteed that the temperature in the ultralow-temperature refrigerator is kept constant; therefore, the samples placed in the sample cells can be well stored.

The utility model relates to a pressure relief device technical field, concretely relates to a kind of super-low temperature refrigerator electromagnetic compression pressure relief device, comprising: pressure relief part, including the cover plate being installed in the inside of box door, the cover plate is equipped with air passage valve subassembly, and the air passage valve subassembly inner end side inserts the pre-buried sleeve for the pressure conduction of box inside and outside;The cover plate is rotatably installed with ferromagnetic pressing plate through base, and electromagnet is installed on the base;When the electromagnet attraction, the ferromagnetic pressing plate oppresses the air passage valve subassembly and carries out pressure relief;The super-low temperature refrigerator electromagnetic compression pressure relief device, by the pressure relief part equipped with electromagnet and spring pressure relief collaborative operation can be realized, improves the reliability, stability of pressure relief operation, can have the realization of active pressure relief and passive pressure relief combination;The passive pressure relief function is still had after single electromagnet failure in the present application, improves the service life of equipment, and the device can guarantee that the pressure relief passage avoids the problem of icing blockage.

The utility model belongs to the technical field of refrigerators, and particularly relates to a foaming box body for a horizontal ultralow-temperature refrigerator. Comprising a first foaming layer, a second foaming layer and a box shell, the box shell is mounted outside the second foaming layer; the second foaming layer is sleeved on the first foaming layer; the first foaming layer wraps the outer vertical face of the low-temperature lining, a fixing assembly is arranged in the first foaming layer, one side of the fixing assembly is detachably connected with the outer vertical face of the low-temperature lining, and the other side of the fixing assembly is fixedly connected with the tubular heat exchanger. The foaming box body is simple in structure and easy to manufacture, the installation precision of the tubular heat exchanger is improved, and the yield of the foaming box body is improved.

The utility model relates to an air inlet valve for air balance, an air balance device and an ultralow-temperature refrigerator, and belongs to the technical field of refrigeration equipment. The air inlet valve comprises a valve body and a plugging piece. A valve cavity is formed in the valve body, and an air inlet and an air outlet connector are formed in the valve body. A guide part is arranged in the air inlet and divides the air inlet into a guide channel located in the guide part and an air inlet channel located between the guide part and the air inlet; the plugging piece is arranged in the valve cavity and comprises a sealing part and a guide part; the sealing part floats up and down in the valve cavity under the action of airflow flowing in from the air inlet channel, and falls to cover the air inlet to seal the air inlet channel without the action of airflow; the guide part is arranged in the guide channel and is in sliding fit with the guide channel; the top end of the guide part is connected to the bottom of the sealing part to move up and down along with the sealing part; the air inlet valve adopts the plugging piece with a novel structure and is provided with the guide structure for guiding the plugging piece to fall, and an air inlet with a relatively large size can be designed so as to meet the requirement of rapidly balancing air pressure.

The invention discloses a method for screening Yili horse mammary gland development key genes and application thereof, and belongs to the field of genomics and molecular breeding. The method comprises the following steps: step 1, selection and treatment of experimental Yili horses: slaughtering the Yili horses in the early lactation period and the peak lactation period, collecting breast tissue samples, putting the breast tissue samples into a cryopreservation tube, putting the cryopreservation tube into liquid nitrogen, taking the cryopreservation tube back to a laboratory, and putting the cryopreservation tube into an ultralow-temperature refrigerator; step 2, carrying out RNA extraction on the Ili horse mammary gland tissue, constructing an ATAC library, an RNA library, a CUT-Tag library and an STRIPE library, and carrying out sequencing; and step 3, carrying out conjoint analysis on the sequencing data in the step 2, and mining key genes related to lactation. The invention also provides application of the method in a horse variety breeding process. The Yili horse mammary gland development and lactation related genes are excavated through a multi-omics technology, the blank in the prior art is filled, a target spot is provided for molecular marker-assisted breeding, and breeding of high-yield and high-quality horse varieties is accelerated.

The invention relates to the technical field of sample library management, and discloses an intelligent sample management system for an ultralow-temperature refrigerator, and the system comprises a personnel and organization structure management module which is used for creating a research group and configuring authority; the refrigerator space planning management module is used for linking a refrigerator for storing samples and dividing and quantifying the structure of the refrigerator; the refrigerator space distribution management module is used for receiving the sample registration information and distributing the cryopreservation boxes; after distribution is completed, sample storage information is updated; the refrigerator space use condition tracking management module is used for receiving the cryopreservation box application information and judging whether a request corresponding to the cryopreservation box application information is executed or not; the refrigerator security access management module is used for verifying the identity information of the currently used researcher, and if the verification is passed, the refrigerator is unlocked; otherwise, the refrigerator is locked; and the refrigerator safety state management module is connected to the intranet server and used for monitoring the working parameters in the refrigerator and giving an alarm if the working parameters are abnormal.

Disclosed herein are methods of making an implant material, the method involving harvesting allograft cancellous bone containing bone marrow from a donor within 24 hours of death; incubating the harvested allograft cancellous bone in an ultra-low freezer within 144 hours of death for at least 5 days; and then selectively lysing cells in the cancellous bone. This results in cancellous bone that is enriched for cells resistant to lysing, such as mesenchymal cells as well as a lysate containing factors (e.g. growth factors) released from the lysed cells. This lystate can be administered to cortical bone, e.g. demineralized cortical bone, with hydrochloric acid (HCI) or glycolytic acid so that these factors attach to the demineralized bone.