2results about How to "Guaranteed build stability" patented technology

This invention discloses a system and method for continuous communication and dynamic sampling of plant volatiles. The system includes a device support system, an air purification and driving system, an airflow distribution and control system, a multi-channel plant chamber, a three-way valve switching system, a drying and sampling interface system, and a collection and negative pressure system. The air purification and driving system purifies the airflow and is connected to the airflow distribution and control system to provide purified airflow. The airflow distribution and control system is connected to the multi-channel plant chamber. The drying and sampling interface system is connected to the collection and negative pressure system to collect the sampled airflow and discharge it through negative pressure. The collection and negative pressure system is connected to the multi-channel plant chamber to form a continuous airflow path through all systems. This invention achieves dynamic sampling and parallel experimentation while maintaining continuous communication of plant volatiles.

The application belongs to the technical field of animal experiment models, and discloses a method for constructing a mouse model of autism spectrum disorder and application. Pregnant mice are orally exposed to different doses of 1-NP every day during the whole gestation period, the pregnant mice naturally give birth, and the offspring mice are evaluated for autism-like behaviors at PND28 after birth by using a three-chamber social experiment. The offspring mice are evaluated for autism-like behaviors at PND70 after birth by using a three-chamber social experiment. Maternal 1-NP exposure during pregnancy delays the migration of intermediate neurons in the forebrain of fetal mice, and the autism-like behaviors. 1-NP exposure during pregnancy down-regulates the expression of intermediate neuron migration-related genes by reducing DNA hydroxymethylation of the intermediate neuron migration-related genes. 1-NP exposure during pregnancy damages the synthesis of mitochondrial tricarboxylic acid cycle alpha-ketoglutarate (alpha-KG). Maternal alpha-KG supplementation during pregnancy improves the migration of intermediate neurons in 1-NP exposed fetal mice and the autism-like behaviors of offspring mice.