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'Shuanghuang' antiphlogistic drop pill in use relieving inflammation and preparation method

A technology of Huang Xiaoyan Dropping Pill and Scutellaria baicalensis, which is applied in the directions of pill delivery, digestive system, and resistance to vector-borne diseases, etc., can solve the problems of bioavailability of first-pass effect of liver and intestine, not conducive to improving the ability of patients to seek medical treatment, and detrimental to overall health level, etc. , to achieve the effect of benefiting labor protection and environmental protection, improving bioavailability, and drug safety

Inactive Publication Date: 2007-10-10
CP PHARMA QINGDAO CO LTD
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

[0007] Due to the preparation technology and other reasons, the oral preparations of most drugs, especially the oral preparations of traditional Chinese medicine, have problems such as long dissolution time, low dissolution rate, poor absorption, hepatic and intestinal first-pass effect and low bioavailability after taking. , thus affecting the efficacy of the drug and directly affecting the therapeutic effect
[0008] In addition, conventional oral dosage forms, such as tablets, capsules, etc., will produce relatively large dust pollution due to the granulation process in the preparation process, which will cause harm to the health of the staff to a certain extent, and will also cause harm to the human body. some pollution to the environment
Furthermore, the production process of conventional oral preparations is complicated and the production cost is high, so that the cost of medication for patients is also increased, which is not conducive to improving the ability of patients to seek medical treatment, and is also not conducive to improving the overall health level of society.

Method used

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Examples

Experimental program
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Effect test

Embodiment Construction

[0029] Now with several groups of specific examples, the preparation method of Shuanghuangxiaoyan dropping pills of the present invention will be further described.

[0030] Group 1: Tests with a single matrix

[0031] 1. Preparation of the drug extract: Prepare according to the preparation method 1, and obtain the dry powder of the extract containing the active ingredients of two traditional Chinese medicines such as Sankezhen and Scutellaria baicalensis for use;

[0032] 2. Substrate: polyethylene glycol (2000、4000、6000、8000、10000、20000) , polyoxyl 40 stearate, beta cyclodextrin, poloxamer, sodium carboxymethyl starch, sodium lauryl sulfate, stearic acid, sodium stearate, glycerin gelatin, shellac, etc. One or a mixture of two or more pharmaceutical carriers;

[0033] 3. Proportion: take g or kg as the unit, by weight, drug extract: matrix = 1:1~1:9;

[0034] 4. Prepare according to the process given in [Preparation Method] 4-7 ​​to obtain Shuanghuang Xiaoyan Dropping Pil...

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PUM

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Abstract

A Chinese medicine in the form of dripping pill for treating sore throat, diarrhea, dycentery, etc is prepared from barberry root, scutellaria root and matrix.

Description

technical field [0001] The invention relates to a pharmaceutical composition with anti-inflammatory effect for treating sore throat, diarrhea, dysentery, chronic dysentery and other diseases, in particular to a medicine prepared from three traditional Chinese medicines such as three needles and baicalin Composition Oral formulation. Background technique [0002] According to the ministerial drug standard WS 3 -Shuanghuang Xiaoyan Tablet prepared by the preparation method given in B-0235-90 is a kind of oral tablet with anti-inflammatory effect, which is used to treat sore throat, diarrhea, dysentery, chronic dysentery and other diseases. Verified, with definite curative effect, it is a commonly used drug for clinical and family treatment of such diseases. [0003] The following is the drug standard WS 3 - Formula and process and brief description given in B-0235-90: [0004] Prescription: three needles 450g, Scutellaria baicalensis 150g [0005] Preparation method: For ...

Claims

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Application Information

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IPC IPC(8): A61K9/20A61K36/539A61K36/29A61P11/04A61P1/12A61P31/04
CPCY02A50/30
Inventor 曲韵智
Owner CP PHARMA QINGDAO CO LTD