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Bistort drop pill and preparation method

A technique of ginseng and dripping pills, applied in the directions of pill delivery, plant raw materials, digestive system, etc., can solve the problems of first-pass bioavailability of liver and intestines, not conducive to improving the ability of patients to seek medical treatment, physical harm to staff, etc. The effect of labor protection and environmental protection, improving bioavailability, and no dust pollution

Inactive Publication Date: 2007-11-14
北京博智绿洲医药科技有限公司
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

[0006] Due to the preparation technology and other reasons, the oral preparations of most drugs, especially the oral preparations of traditional Chinese medicine, have problems such as long dissolution time, low dissolution rate, poor absorption, hepatic and intestinal first-pass effect and low bioavailability after taking. , thus affecting the efficacy of the drug and directly affecting the therapeutic effect
[0007] In addition, conventional oral dosage forms, such as tablets, capsules, etc., will produce relatively large dust pollution due to the granulation process in the preparation process, which will cause harm to the health of the staff to a certain extent, and will also cause harm to the human body. some pollution to the environment
Furthermore, the production process of conventional oral preparations is complicated and the production cost is high, so that the cost of medication for patients is also increased, which is not conducive to improving the ability of patients to seek medical treatment, and is also not conducive to improving the overall health level of society.

Method used

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Examples

Experimental program
Comparison scheme
Effect test

Embodiment Construction

[0028] Now with several groups of specific examples, the preparation method of the boxing ginseng dripping pills of the present invention will be further described.

[0029] Group 1: Tests with a single matrix

[0030] 1. Raw materials: Take some industrial finished liquid extracts containing the active ingredients of traditional Chinese medicine boxing ginseng, concentrate them at low temperature (60°C) under reduced pressure (0.1MPa) to a thick paste with a relative density of 1.3-1.35, or continue to dry and crush them into The dry powder is the thick paste or dry powder of the medicinal extract;

[0031] 2. Substrate: polyethylene glycol (2000、4000、6000、8000、10000、20000) , polyoxyl 40 stearate, beta cyclodextrin, poloxamer, sodium carboxymethyl starch, sodium lauryl sulfate, stearic acid, sodium stearate, glycerin gelatin, shellac, etc. One or a mixture of two or more pharmaceutical carriers;

[0032] 3. Proportion: take g or kg as the unit, by weight, drug extract: mat...

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PUM

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Abstract

A Chinese medicine in the form of dripping pill for treating dycentery, enteritis, diarrhea, etc is prepared from bistort rhizome and matrix.

Description

technical field [0001] The invention relates to a pharmaceutical composition with heat-clearing and detoxifying effects for treating diseases such as damp-heat dysentery, enteritis, and heat diarrhea, in particular to a pharmaceutical composition oral dripping pill preparation using ginseng as a raw material of traditional Chinese medicine. Background technique [0002] According to the ministerial drug standard WS 3 - Quanshen Tablet (also known as Purple Ginseng Tablet) prepared by the preparation method given in B-0612-91, is a kind of oral tablet that has heat-clearing and detoxifying effects, and is used to treat damp-heat dysentery, enteritis, heat diarrhea and other diseases It has been clinically verified and has definite curative effect. It is a commonly used drug for clinical and family treatment of such diseases. [0003] The following is the drug standard WS 3 - Formula and process and brief description given in B-0612-91: [0004] Preparation method: take 100...

Claims

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Application Information

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Patent Type & Authority Patents(China)
IPC IPC(8): A61K9/20A61K36/704A61P1/12A61P1/00A61K125/00
CPCY02A50/30
Inventor 曲韵智
Owner 北京博智绿洲医药科技有限公司