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Anshenning dripping pill for treating neurosism and its preparing method

A technology of neurasthenia and Ningdropping Pills, which is applied in nervous system diseases, medical preparations containing active ingredients, pill delivery, etc., can solve the bioavailability of the first-pass effect of the liver and intestines, which is not conducive to improving the ability of patients to seek medical treatment and the health of staff. Hazards and other issues, to achieve the effect of benefiting labor protection, improving bioavailability, and environmental protection

Inactive Publication Date: 2009-06-24
北京博智绿洲医药科技有限公司
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

[0007] Due to the preparation technology and other reasons, the oral preparations of most drugs, especially the oral preparations of traditional Chinese medicine, have problems such as long dissolution time, low dissolution rate, poor absorption, hepatic and intestinal first-pass effect and low bioavailability after taking. , thus affecting the efficacy of the drug and directly affecting the therapeutic effect
However, syrup oral preparations also have disadvantages such as low drug content, difficulty in taking and measuring accurately, inconvenient taking or carrying, etc.
[0008] In addition, conventional oral dosage forms, such as tablets, capsules, etc., will produce relatively large dust pollution due to the granulation process in the preparation process, which will cause harm to the health of the staff to a certain extent, and will also cause harm to the human body. some pollution to the environment
Furthermore, the production process of conventional oral preparations is complicated and the production cost is high, so that the cost of medication for patients is also increased, which is not conducive to improving the ability of patients to seek medical treatment, and is also not conducive to improving the overall health level of society.

Method used

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Examples

Experimental program
Comparison scheme
Effect test

Embodiment Construction

[0032] Now with several groups of specific examples, the preparation method of Anshenning dripping pills of the present invention will be further described.

[0033] Group 1: Tests with a single matrix

[0034] 1. Raw materials: According to [Appendix] and [Preparation Method 1], the dry extract powder containing active ingredients of 3 traditional Chinese medicines such as Acanthopanax, Ganoderma lucidum and Schisandra chinensis was first prepared for use;

[0035] 2. Substrate: polyethylene glycol (1000、2000、4000、6000、8000、10000、20000) , polyoxyl 40 stearate, beta cyclodextrin, poloxamer, sodium carboxymethyl starch, sodium lauryl sulfate, stearic acid, sodium stearate, glycerin gelatin, shellac;

[0036] 3. Proportion: take g or kg as unit, by weight, drug extract: matrix = 1:1~1:9;

[0037] 4. Prepare Anshenning dripping pills of different specifications according to the process given in [Preparation Method] 4-7.

[0038] [test results]

[0039] Experiment 1: In order ...

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PUM

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Abstract

The invention relates to a pharmaceutical composition which has the functions of strengthening the body, strengthening the spleen, nourishing qi and invigorating the spleen, nourishing the kidney and calming the nerves, and is used for the treatment of neurasthenia, loss of appetite, general weakness and the like. The purpose of the present invention is to supplement the deficiencies of the existing oral pharmaceutical preparations for the treatment of neurasthenia, loss of appetite, and general weakness, and to provide a drug with high bioavailability, rapid drug release, rapid effect, and high drug content. Anshenning dripping pills are oral preparations of the pharmaceutical composition with accurate measurement, low price and portability. The Anshenning dripping pills involved in the present invention are prepared from three traditional Chinese medicines such as Acanthopanax senticosus, Ganoderma lucidum and Schisandra chinensis as raw materials, together with a pharmaceutically acceptable carrier as a matrix.

Description

technical field [0001] The present invention relates to a kind of pharmaceutical composition which has the functions of strengthening the body, nourishing qi and invigorating the spleen, nourishing the kidney and calming the nerves, and is used for the treatment of neurasthenia, loss of appetite, general weakness and other diseases. An oral preparation of a pharmaceutical composition prepared from traditional Chinese medicines. Background technique [0002] Anshenning syrup prepared according to the preparation method given in the ministerial drug standard WS3-B-0276-90 is a kind of syrup that has the functions of strengthening the body, strengthening the spleen, nourishing the kidney and calming the nerves, and is used for neurasthenia and loss of appetite. , a syrup-based oral preparation for the treatment of general weakness and other diseases, has been clinically verified and has definite curative effects. It is a commonly used drug for clinical and family treatment of t...

Claims

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Application Information

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Patent Type & Authority Patents(China)
IPC IPC(8): A61K36/57A61K36/254A61K36/074A61K9/20A61P1/14A61P25/20
Inventor 曲韵智
Owner 北京博智绿洲医药科技有限公司