Optical detection device and working method for tissue of living body

A living tissue and optical detection technology, applied in medical science, diagnostic recording/measurement, diagnosis, etc., can solve the problems of not considering the absorption characteristics of chromophores, missed or misdiagnosed, and inability to detect and diagnose tissues in the body

Inactive Publication Date: 2007-10-10
马剑文 +3
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

The disadvantage of this technical solution is that this solution only considers the scattering characteristics of light on tissue cells, and does not consider the light absorption characteristics of chromophores in tissue bodies, which leads to low reliability of its measurement results and easily leads to missed or misdiagnosed
The disadvantage of this solution is that it mainly obtains the characteristics of the tissue by detecting the transmission spectrum, which is similar to X-ray breast detection. This method needs to compress the breast tissue to a certain extent before the detection can start, which brings certain pain to the patient. , and cannot detect and diagnose in vivo tissues
The disadvantage of this system is: when the computer in the system is working, it uses the light received by the monitor system to analyze the physical characteristics of the measured surface layer, and at the same time, the change of the light intensity is used as the feedback signal of the light source, and the light source is controlled by the controller. Output stability, this kind of feedback control is more complicated, and the electrical signal control often has a serious feedback lag, resulting in unstable output of the light source, which in turn leads to a large detection error of the system
In addition, the system cannot compare the light intensity of each wavelength output by the light source with the light intensity of the diffuse reflection light from the tissue surface, resulting in a large deviation in the diffuse reflection spectrum obtained by the computer that can be used to analyze the physical properties of biological tissues, and even cannot be used. diffuse reflectance spectrum, so the reliability of the system is not high
[0011] The disadvantage of the above prior art is that it can only optically detect the living tissue of a single depth, but the actual situation is that the living tissue of the disease has a certain horizontal area and longitudinal depth, and the living tissue of a single depth can only be detected by optical detection. Optical detection clearly cannot accurately detect the status of neoplastic lesions in living tissue

Method used

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  • Optical detection device and working method for tissue of living body
  • Optical detection device and working method for tissue of living body
  • Optical detection device and working method for tissue of living body

Examples

Experimental program
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Embodiment 1

[0049] (Example 1, living tissue optical detection device)

[0050] Referring to FIG. 1 , the living tissue optical detection device of this embodiment has a main detection device and a diffuse reflection plate 6 independent of the main detection device. The main detection device includes the main body of the main detection device; the main body of the main detection device has a light source emitting unit 1, an optical fiber probe 2, a spectral analysis and data processing unit 3, a transmitting optical fiber 4, a receiving optical fiber 5 and an optical switch 7.

[0051] The light source emitting unit 1 is a device that emits light with a wavelength range of 400 to 1000 nanometers when in use (the light emitted in this embodiment has a continuous white light spectrum when used, and its wave bands are visible light and near-infrared. You can also choose to emit continuous visible light. Light source emitting unit 1, or select the light source emitting unit 1 that emits a con...

Embodiment 2

[0064] (Example 2, living tissue optical detection device)

[0065] See Figure 7, Figure 4-2 and Figure 5-2, the rest are the same as in Embodiment 1, the difference is that in this embodiment, the transmitting optical fiber 4 is changed to a single optical fiber, and the receiving optical fiber 5 is divided into two sections before and after , the front section 51 of the receiving optical fiber 5 is an optical fiber bundle with 3 optical fibers (in other embodiments, it can be any possible value greater than 3, such as 6, 10, 20, etc., or it can be 2, and the corresponding optical switch 7 The number of branches at the branch end 72 is not less than the number of optical fibers), and the rear section 52 of the receiving optical fiber 5 is a single optical fiber. The number of optical switches 7 is still one.

[0066] See Fig. 4-2 and Fig. 5-2, in the present embodiment, the front end of the emitting fiber 4 is connected to the light source output end of the light source emit...

Embodiment 3

[0068] (Embodiment 3, living tissue optical detection device)

[0069] See Figure 8, Figure 4-3 and Figure 5-3, the rest are the same as in Embodiment 1, the difference is that the receiving optical fiber 5 is divided into front and rear sections, and the front section 51 of the receiving optical fiber 5 is an optical fiber bundle with 2 optical fibers , the rear section 52 of the receiving optical fiber 5 is a single optical fiber. The number of optical switches 7 is 2, and the first optical switch 7 is arranged in series by its optical port between the rear end of the optical fiber of the front section 41 of the launching optical fiber 4 and the front end of each optical fiber of the rear section 42 of the launching optical fiber 4, The second optical switch 7 is arranged in series between the rear end of each optical fiber in the front section 51 of the receiving optical fiber 5 and the front end of the optical fiber in the rear section 52 of the receiving optical fiber 5 t...

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Abstract

An optical test device for the tissue of living body is composed of light emitter unit, optical fiber probe, optical spectrum analyzing and data processing unit, emitting optical fibers, receiving optical fibers, and optical switch. Its detecting method is also disclosed.

Description

technical field [0001] The invention relates to a device for detecting living tissue and a working method thereof. The results obtained after detection can be used by medical personnel to perform optical detection of tumors in living tissues and the like. Background technique [0002] The non-invasive detection of the human body, especially the tissue in the human tissue, is of great significance in clinical medicine, especially the non-destructive and rapid diagnosis of various tumors, which is of great significance for early diagnosis and improving the survival rate of cancer patients. [0003] Doctors' diagnosis of cancer is mostly based on experience and examination of biopsies, which has a certain degree of subjectivity and blindness, resulting in early-stage lesions being easily missed or misdiagnosed. [0004] Laser medicine is an emerging discipline of modern medicine. It integrates high and new technologies in the fields of laser, spectroscopy, fiber optics, optica...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): A61B5/06A61B5/00
Inventor 马剑文王成徐安成马博平
Owner 马剑文
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