Human epiterm growth-factor receptor mutation gene and use thereof

A technology of epidermal growth factor and mutant gene, applied in genetic engineering, plant gene improvement, application, etc., can solve the problems of lack of prognosis evaluation mode for treatment methods, influence of drug efficacy, and non-utilization
CN101070538AInactive Publication Date: 2007-11-14GUANGZHOU INST OF BIOMEDICINE & HEALTH CHINESE ACAD OF SCI
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Patent Information

Authority / Receiving Office
CN · China
Current Assignee / Owner
GUANGZHOU INST OF BIOMEDICINE & HEALTH CHINESE ACAD OF SCI
Publication Date
2007-11-14
Estimated Expiration
Not applicable · inactive patent

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Abstract

This invention relates to the medicine preparation and the gene diagnosis application, especially in non-small cell lung cancer drug targeted therapy Preparation and treatment of non-small cell lung cancer of human epidermal growth factor receptor gene detection applications. Provides many kinds of person epidermal cell growth factor acceptor (EGFR) mutant gene, preparation for Chinese non-small cell lung cancer (NSCLC) targeted therapy drug target genes, gene diagnosis using target, especially for non-small Human cell lung cancer treatment epidermal growth factor receptor gene detection of gene targets, making malignancies, particularly NSCLC gene targeting drugs and the development of diagnostic reagents have a clear role in site, thus enabling more specific targeted therapy , to carry out the individualized cancer treatment.
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Description

technical field

[0001] The present invention relates to a variety of human epidermal growth factor receptor (EGFR) mutant genes and their applications, and to the application of drug preparation and gene diagnosis, especially in the preparation of non-small cell lung cancer targeted therapy drugs and the treatment of non-small cell lung cancer. Application of growth factor receptor gene detection. Background technique

[0002] Malignant tumors are a serious threat to human health, and their treatment has also become the focus of attention. Due to the lack of specificity, traditional chemotherapy and radiotherapy often bring great toxic and side effects to patients while achieving curative effect. For this reason, the research of anti-tumor targeted drugs has attracted people's attention day by day.

[0003] As we all know, currently the commonly used therapeutic targets for targeted therapy of malignant tumors mainly include: cell receptors, signal transduction and anti-an...

Claims

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