Method of preparing concentrated pill of six ingredients with rehmannia
A technology of Liuwei Dihuang Pills and Cortex Moutan, which is applied in the field of preparation of concentrated Liuwei Dihuang Pills, can solve the problems of easy errors, troublesome patients taking medicine, and large number of takings
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[0015] The preparation method of the concentrated Liuwei Dihuang Pills of the present invention includes pretreatment, batching, milling and extraction of raw medicinal materials according to the standard. Concentrate the extracted filtrate to a relative density of 1.38-1.40 / 75°C, add ethanol or a disintegrating agent, and select an appropriate drying process to finally obtain a water content of 5-8%, a dissolution time limit of 55-120 minutes, and a dry pellet weight 0.425g~0.445g / pill, pills with a dry diameter of 8.5~9.2mm / pill.
[0016] According to the quality standards of Liuwei Dihuang Pills in the "Chinese Pharmacopoeia", although the amount of Chinese medicinal materials powdered into the powder is constant, during the extraction process, the difference between batches of medicinal materials will lead to differences in the amount of thick paste in each batch, which in turn will lead to the difference between batches of finished pills. There are certain differences in ...
Embodiment 1
[0027] Prescription: Rehmannia glutinosa 320g, Cornus officinalis (made) 160g, Peony 120g, Chinese yam 160g, Poria cocos 120g, Alisma 120g.
[0028] The preparation process is as follows: according to the prescription, take nine medicinal materials such as Rehmannia glutinosa, Cornus officinalis, Peony, Chinese yam, Poria cocos and Alisma alisma, extract paeonol from Moutan cortex; Decoction twice, each time for two hours, the filtrate is concentrated to a thick paste with a density of 1.32-1.40, the yam and the remaining dogwood are crushed into fine powder, sieved, and mixed; then the above thick paste, fine powder, paeonol , Auxiliary material mixing, the 93% ethanol that adds is made soft material, and the amount of adding ethanol is 1.2% of fine powder, medicinal extract, paeonol total amount, makes wet pill, and average pill weight is 0.477g / pill, adopts oven Dry with vibration drying, polish, get average ball diameter 8.5mm / ball, average ball weight is the product 100...
Embodiment 2
[0030]Prescription: Rehmannia glutinosa 320g, Cornus officinalis (made) 160g, Peony 120g, Chinese yam 160g, Poria cocos 120g, Alisma 120g.
[0031] The preparation process is as follows: according to the prescription, take nine medicinal materials such as Rehmannia glutinosa, Cornus officinalis, Peony, Chinese yam, Poria cocos and Alisma alisma, extract paeonol from Moutan cortex; Decoction twice, each time for two hours, the filtrate is concentrated to a thick paste with a density of 1.32-1.40, the yam and the remaining dogwood are crushed into fine powder, sieved, and mixed; then the above thick paste, fine powder, paeonol , auxiliary material mixing, the 95% ethanol that adds is made soft material, and the amount of adding ethanol is 1.5% of fine powder, extractum, paeonol total amount, makes wet pill, and average pill weight is 0.483g / pill, adopts microwave Drying with an oven, polishing, to get an average pill diameter of 9.2mm / pill, and an average pill weight of 1000 p...
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