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Purslane extract as well as preparation method and application thereof

A technology of purslane and extract, applied in the field of medicine, can solve the problems of inconvenience in taking, excessive dosage, restriction, etc., and achieve the effects of low cost, huge social and economic benefits, and no organic solvent residue.

Inactive Publication Date: 2008-05-21
SECOND MILITARY MEDICAL UNIV OF THE PEOPLES LIBERATION ARMY
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

However, if the original medicinal material or total extract of purslane is used as medicine, there will be problems such as excessive dosage, inconvenient taking, and unacceptable, and the application is severely restricted.
At present, there is no report on the chemical composition and pharmacological research of the precipitate produced after centrifugation in the process of extracting purslane

Method used

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Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0024] Embodiment 1 prepares purslane extract

[0025] Purslane medicinal material coarse powder 1kg, with 80% ethanol, 10 times, 8 times, 8 times, 1.5 hours, 1 hour, 1 hour, reflux extraction, extract while hot filter, combine extract, decompress and recover solvent to nothing Alcoholic taste, adjust the concentration to 1g (crude drug) / ml with distilled water, adjust the pH value to 7.6 with 10% NaOH solution, 5000rpm, 1 minute, centrifuge, separate and collect the precipitate, vacuum dry at 60°C for 8h, and pulverize to obtain 20.90g of the extract. Adopt HPLC method to detect: Shimadzu LC-20AD high performance liquid chromatograph (equipped with quaternary gradient system, DAD detector), mobile phase: methanol-acetonitrile-0.5% phosphoric acid aqueous solution (66%: 22%: 12%) , column temperature: 26°C; detection wavelength: 210nm; flow rate: 1.10 ml / min, the results show that the contents of linolenic acid and linoleic acid in the extract of the present invention are 1.25...

Embodiment 2

[0026] Embodiment 2 prepares purslane extract

[0027] Purslane medicinal material coarse powder 1kg, water is used as extraction solvent, all the other are the same as in Example 1, 31.64g of extract are obtained, the content of linolenic acid and linoleic acid are respectively 0.96% and 0.26%.

Embodiment 3

[0028] Embodiment 3 prepares purslane extract

[0029] Purslane medicinal material coarse powder 1kg, the concentrated solution does not adjust the pH value, the rest is the same as in Example 1, to obtain 42.54g of extract, the content of linolenic acid and linoleic acid are respectively 2.79% and 1.27%.

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PUM

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Abstract

The invention relates to the technical field of medicine, in particular to an extractive produced by applying the Chinese traditional medicine of purslane as raw material and an extracting method thereof in addition to medicine and food made of the extractive for resisting oxygen lack, fatigue and stress. Common extractive of the purslane is distilled by water or alcohol, the supernatant fluid is adopted, and the deposit produced by centrifuging is considered as useless and discarded. After discovering that after proper concentration of the purslane by the water or alcohol extracting liquid, the deposit produced by centrifuging has distinct effects in resisting oxygen, fatigue and stress. The invention provides a novel method for preparing the extractive of the purslane. Being proven by tests, the extractive of the purslane produced by the method has good effects in resisting oxygen, fatigue and stress.

Description

technical field [0001] The invention relates to the technical field of medicine, in particular to an extract prepared from the traditional Chinese medicine purslane and an extraction method, and the extract is used to prepare anti-hypoxia, anti-fatigue, and anti-stress medicines and food. Background technique [0002] Purslane (Portulaca oleracea L.) is a purslane plant, also known as purslane, five elements grass, longevity vegetable, nine lion grass, sour vegetable, etc., widely distributed in temperate and tropical regions of the world, and is a medicinal food Dual purpose plants. The traditional Chinese medicine purslane is used as medicine with its aerial parts. It is sour in taste and cold in nature. It has the effects of clearing away heat and detoxifying, cooling blood and reducing swelling. Modern pharmacological studies have shown that purslane has antibacterial, blood fat-lowering, anti-aging, anti-oxidation, muscle relaxation, anti-inflammatory, analgesic and wo...

Claims

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Application Information

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IPC IPC(8): A61K36/185A61P39/06A23L1/30
Inventor 凌昌全李敏辛海量岳小强王万银徐燕丰侯银环
Owner SECOND MILITARY MEDICAL UNIV OF THE PEOPLES LIBERATION ARMY
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