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í«Erdongí» oral preparation and preparation thereof

A technology for oral preparations and preparations, which is applied in the field of oral preparations with extracts as active pharmaceutical ingredients, and can solve the problems of inaccurate dosage, large dosage of traditional Chinese medicine decoction, and inability to commercialize.

Inactive Publication Date: 2008-08-13
张文芳
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

[0013] The ancient "Erdong Decoction" only had decoctions, which needed to be decocted and taken after purchasing decoction pieces. It was very inconvenient to carry and take it. After research, we made modern oral preparations of traditional Chinese medicine through quantitative control of index components. The product dosage is accurate and the quality is stable. It is convenient to take and is suitable for large-scale commercial production. It overcomes the shortcomings of traditional Chinese medicine decoctions such as large dosage, inaccurate dosage, inconvenient carrying and taking, and inability to commercialize. It is convenient for clinical treatment and home use.

Method used

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Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0044] Embodiment one: "Erdong" extract 1 (extract) preparation method

[0045] Prescription: 12 parts of Radix Asparagus, 12 parts of Ophiopogon japonicus, 12 parts of Tianhuafen, 10 parts of Scutellaria baicalensis, 10 parts of Anemarrhena, 6 parts of licorice, 6 parts of ginseng, and 3 parts of lotus leaf.

[0046] Preparation method: cleanly select the medicinal materials of the prescription, weigh each medicinal material according to the prescription amount, add 6-15 times the amount of water to soak for 2-10 hours, heat and boil for 2-3 times, and combine the extracts; the water extracts stand still After 12-48 hours, filter the supernatant, concentrate under reduced pressure to obtain about 14.2 g of water extract.

Embodiment 2

[0047] Embodiment two: "Erdong" extract 2 (dry powder) preparation method

[0048] Prescription: Asparagus 6 parts, Radix Ophiopogon japonicus 9 parts, Trichosanthum Fen 3 parts, Scutellaria baicalensis 3 parts, Anemarrhena 3 parts, Licorice 1.5 parts, Ginseng 1.5 parts, Lotus leaf 3 parts.

[0049] Preparation method: cleanly select the medicinal materials of the prescription, weigh each medicinal material according to the prescription amount, add 8-10 times the amount of water to soak for 2-8 hours, heat to boiling and extract 2-3 times, combine the extracts; the water extracts stand still After 12-48 hours, the supernatant was collected by filtration, concentrated under reduced pressure, and spray-dried to obtain about 6.0 g of water extract as a dry powder.

Embodiment 3

[0050] Embodiment three: "Erdong" oral solid preparation preparation method

[0051] (1) Preparation of "Erdong" Granules

[0052] prescription:

[0053] "Erdong" Extract 110-90%

[0054] Starch 5.0-70%

[0055] Dextrin 2.0-20%

[0056] Xylitol 5.0-20%

[0057] Methyl sorbate 0.001-2.0%

[0058] Preferred Prescription:

[0059] "Erdong" Extract 1 14.2g

[0060] Starch 3.0g

[0061] Dextrin 3.0g

[0062] Xylitol 2.0g

[0063] Methyl sorbate 0.002g

[0064] Preparation method: prepare the "Erdong" extract according to the method in Example 1, add prescription amount of excipients to make granules according to conventional methods, dry at low temperature, and pack.

[0065] (2) Preparation of "Erdong" tablet:

[0066] (1) Ordinary tablet prescription:

[0067] "Erdong" Extract 2 5.0-90%

[0068] Starch 5.0-50%

[0069] Dextrin 2.0-20%

[0070] Microcrystalline Cellulose 5.0-20%

[0071] Talc 0.5-5.0%

[0072] Magnesium stearate 0.1-5.0%

[0073] Preferred Pre...

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PUM

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Abstract

The present invention relates to an erdong oral preparation and a method for preparing the same. The oral preparation is prepared from mixed extract (extractum or dry powder) including tiandong, liriope, trichosanthin, radix astragali, common anemarrhena, liquorice, genseng, lotus leaf as raw materials, and acceptable carrier or excipient as substrate in medicine by conventional process. The preparation has effects of nourishing yin and moisting lung, encouraging production of body fluids to extinguishthirst, cleaning wine heat, nourishing yin liquid, strengthening the spleen in transportation and protecting liver and stomach for treating diabetes involving upper, thirsty symptom etc.

Description

technical field [0001] The invention belongs to the technical field of medicine, and specifically relates to an oral preparation for treating mainly Shangxiao and thirsty polydipsia and a preparation method thereof, in particular to an oral preparation using the extract of Erdong traditional Chinese medicine prescription as the active ingredient of the medicine. Background technique [0002] "Erdong Decoction" was created in Qing Cheng Guopeng's "Medical Mind Awareness". It has always been used as a common prescription for dry mouth and thirst, frequent drinking more water and thirst, and it lasts for many days. Scutellaria baicalensis, Anemarrhena, licorice, ginseng, and lotus leaves have the functions of nourishing yin and moistening lungs, promoting body fluids and quenching thirst, warming wine, nourishing yin dregs, invigorating spleen and helping transportation, and protecting liver and stomach. The effect of drinking card. [0003] The sources of Chinese medicinal ma...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): A61K36/8968A61K9/08A61K9/10A61K9/16A61K9/20A61K9/48A61K47/14A61K47/36A61K47/40A61K47/44A61P1/14A61P1/16A61P3/10
Inventor 张文芳曹世栋
Owner 张文芳
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