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Preparation of IgG riched-containing bovine colostrum

A technology of bovine colostrum powder and colostrum, applied in dairy products, food preparation, other dairy products, etc., can solve the problems of long process flow, inactivation of immunoglobulin, unsuitable for industrial mass production, etc., and achieve short process Effect

Inactive Publication Date: 2008-08-27
JIANGSU XINGCHI BIOTECH
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

[0006] The preparation method of bovine colostrum has been reported in Chinese patent documents. For example, CN1336120A discloses an active colostrum health product and a production method thereof. Since this method adds lactose to liquid A, it is not suitable for people with lactose incompatibility. Because adverse reactions such as diarrhea may occur after taking
In addition, the applicant has not seen in the existing literature about the appropriate sterilization temperature and time for IgG, because the sterilization temperature is too high and the time is too long will often cause the inactivation of immunoglobulins
In particular, the technology used in the existing method of preparing bovine colostrum can only make the IgG content reach 18-20%, and it is almost impossible to increase it, and the process is long and costly, which is not suitable for industrial mass production

Method used

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Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0024] A). Prepare raw materials, select or collect the colostrum secreted by healthy and disease-free dairy cows within three days of calving, that is, bovine colostrum, and immediately place the bovine colostrum in a freezing device such as a freezer or refrigerator or other Store in a similar device at a storage temperature of -4°C to obtain raw materials for use;

[0025] B). Remove fat and lactose, get the bovine colostrum 10kg that is obtained by step A) drop into the container that fills the Nacl solution that concentration is 8%, fully stir evenly, adopt centrifuge separation then, the rotating speed of centrifuge The centrifugation time is 3500n / min, and the centrifugation time is 20min. After the centrifugation, let stand to settle, and then remove the fat in the upper layer and the lactose-containing solution in the middle layer to obtain the protein-containing precipitate in the lower layer;

[0026] C). For the separation of protein-containing precipitates, first ...

Embodiment 2

[0029] A). Prepare raw materials, select or collect healthy and disease-free dairy cows that secrete colostrum within three days after calving, and quickly place bovine colostrum in a freezing device such as a freezer or refrigerator or other similar Store in the device, storage temperature is -2 ℃, obtain raw material, stand-by;

[0030] B). Remove fat and lactose, get the bovine colostrum 10kg that is obtained by step A) drop into the container that fills the Nacl solution that concentration is 8.5%, fully stir evenly, adopt centrifuge separation then, the rotating speed of centrifuge The centrifugation time is 3750n / min, and the centrifugation time is 15min. After the centrifugation, let stand to settle, and then remove the fat in the upper layer and the lactose-containing solution in the middle layer to obtain the protein-containing precipitate in the lower layer;

[0031] C). For the separation of protein-containing precipitates, first dissolve the protein-containing prec...

Embodiment 3

[0034] A). Prepare raw materials, select or collect healthy and disease-free dairy cows that secrete colostrum within three days after calving, and quickly place bovine colostrum in a freezing device such as a freezer or refrigerator or other similar Store in the device, storage temperature is 0 ℃, obtain raw material, stand-by;

[0035] B). Remove fat and lactose, get the bovine colostrum 10kg that is obtained by step A) and drop into the container that fills the Nacl solution that concentration is 9%, fully stir evenly, adopt centrifugal separator to separate then, the rotating speed of centrifugal separator The centrifugation time is 4000n / min, and the centrifugation time is 10min. After the centrifugation, let stand to settle, and then remove the fat in the upper layer and the lactose-containing solution in the middle layer to obtain the protein-containing precipitate in the lower layer;

[0036]C). For the separation of protein-containing precipitates, first dissolve the ...

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Abstract

A method for preparing bovine colostrum powder with rich IgG belongs to the preparative technology field of health products, and includes the following steps: preparing material, in which step the bovine colostrum lactated in 3 days after the cow parturition day is chosen and stored at a low temperature to obtain the material; removing fat and lactose, in which step the material is put into salt solution with a light concentration and stirred, and then thrown into a centrifugal device to separate and remove the supernatant fat and the medial solution with the lactose, thereby obtaining a precipitate with albumen; separating the precipitate with the albumen, in which step the precipitate with the albumen is dissolved in clean water, and then thrown into the centrifugal device to be centrifugally processed after the pH value is adjusted with acid, a precipitate is rejected and supernate is extracted and adjusted with alkali to obtain IgG liquid; and carrying out sterilization and dryness with the IgG liquid to obtain the bovine colostrum powder product. The preparation method has the advantages that the technique is brief and is suitable for industrialized production in batch quantity, and the IgG content of the obtained bovine colostrum powder is above 30%.

Description

technical field [0001] The invention belongs to the technical field of preparation of health care products, and in particular relates to a preparation method of bovine colostrum powder rich in IgG. Background technique [0002] Bovine colostrum, also known as latex milk, is the milk secreted by cows within three days after giving birth. Bovine colostrum is yellow in color, has a bitter taste and a peculiar smell, and its protein, fat, inorganic salts, vitamins, etc. are significantly higher than conventional milk. Because bovine colostrum is rich in active ingredients such as immune factors and growth factors, it has high nutritional value and physiological immune function or regulatory function. [0003] Scientific research shows that the protein content and fat content of bovine colostrum are 5 times and 2 times that of conventional (ordinary milk) respectively. The content of mineral elements in bovine colostrum is also high, such as calcium, magnesium, phosphorus, zinc...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): A23C9/16A23C9/15A23C7/00A23C3/00A23L1/29A23L33/00
Inventor 顾培华
Owner JIANGSU XINGCHI BIOTECH
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