Unlock instant, AI-driven research and patent intelligence for your innovation.

Method for extracting main active components of mulberry leaf and application of its extract

The technology of a mulberry leaf extract and an extraction method is applied in the fields of phytochemistry, the modernization of traditional Chinese medicine, and the prevention and treatment of diabetes, and can solve the problems of incomplete extraction and utilization of mulberry leaf active components, cumbersome technological process, inability to separate effective components, etc. The effect of simple preparation process and easy operation

Inactive Publication Date: 2012-05-30
东莞市唐百服生物科技有限公司 +1
View PDF5 Cites 2 Cited by
  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

However, there are certain deficiencies in these methods: either the extraction and utilization of the effective components of mulberry leaves are not complete, or the process is cumbersome, and it is impossible to separate all the main active components by one adsorption

Method used

the structure of the environmentally friendly knitted fabric provided by the present invention; figure 2 Flow chart of the yarn wrapping machine for environmentally friendly knitted fabrics and storage devices; image 3 Is the parameter map of the yarn covering machine
View more

Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0023] Mulberry leaves 10kg, cut into pieces, boiled in water for 30 minutes to extract twice, 50L each time. The extract was left to cool to room temperature, and the supernatant was passed through a D72 resin column (column volume 10L), washed with 10L of water and then eluted with 20L of ethanol, and then eluted with 30L of 1% ammonia / ethanol water (containing 70% ethanol) solution . After the ammonia water ethanol eluent is recovered to be free of ammonia, the previous 20L ethanol eluent is added to recover to a volume of 3L to obtain a liquid extract.

[0024] After most of the water was evaporated to 3L, the resin was precipitated by adding 7L of ethanol. The supernatant was removed by centrifugation, mixed with the liquid extract above, vacuum-dried, and pulverized to obtain 300 g of yellow powder with a yield of 3%.

[0025] Get 100g of mulberry leaf extract, add starch 3000g, microcrystalline cellulose 30g, granulate with 50% ethanol, compress into tablets to obtain...

Embodiment 2

[0027] 10kg of mulberry leaves, cut into pieces, boiled with 50% ethanol / water for 30 minutes to extract twice, 50L each time. After the extract was concentrated to recover ethanol, it was diluted with 100 L of water, and then passed through a D72 resin column (column volume 10 L). According to the method described in Example 1, 400 g of yellow powder was obtained with a yield of 4%, which was the mulberry leaf extract referred to in the present invention.

the structure of the environmentally friendly knitted fabric provided by the present invention; figure 2 Flow chart of the yarn wrapping machine for environmentally friendly knitted fabrics and storage devices; image 3 Is the parameter map of the yarn covering machine
Login to View More

PUM

No PUM Login to View More

Abstract

The invention relates to a method for extracting the main active components of mulberry leaves and the application of extract, belonging to phytochemistry, Chinese medicine modernization and the field of preventing and treating diabetes mellitus. The invention is characterized in that only one resin is required and three kinds of the active components of the mulberry leaves, which are alkaloids, flavonoids and polysaccharide, are completely extracted by one extraction process. Therefore, the extracting method has simple technique and low cost. The preparation method comprises processes of extraction, adsorption, elution and drying. The main active components of the extract prepared by the method are the alkaloids, the flavonoids and the polysaccharide extracted from the mulberry leaves. The extract can be used as granule without excipient added or be used as the medicine or functional food with one or a plurality of edible excipient added, such as starch, microcrystalline cellulose, dextrin, sucrose, lactose, Vitamin C, citric acid and sodium sulfite, for preventing and treating diabetes mellitus and the complication of diabetes mellitus and obesity and treating viral col.

Description

technical field [0001] The invention relates to a method for extracting main active components of mulberry leaves and the application of the extract in preventing and treating diabetes and its complications, obesity and treating viral colds, belonging to the fields of phytochemistry, modernization of traditional Chinese medicine, and prevention and treatment of diabetes. Background technique [0002] Diabetes mellitus is a progressive endocrine disease with glucose metabolism disorder as the main symptom group. The basic pathophysiology is the relative deficiency or absolute deficiency of insulin secretion function in the body or the abnormal function of insulin receptor, which causes metabolic disorder, including sugar, protein, Fat, water and electrolytes etc. The general manifestations are hyperglycemia, diabetes and hyperlipidemia. In severe cases, ketoacidemia may occur, and even circulatory attenuation and coma are life-threatening. Diabetes is divided into four categ...

Claims

the structure of the environmentally friendly knitted fabric provided by the present invention; figure 2 Flow chart of the yarn wrapping machine for environmentally friendly knitted fabrics and storage devices; image 3 Is the parameter map of the yarn covering machine
Login to View More

Application Information

Patent Timeline
no application Login to View More
Patent Type & Authority Patents(China)
IPC IPC(8): A61K36/605A61K9/16A61K47/38A23L1/29A61P3/10A61P3/04A61P31/12A23L33/00
Inventor 王明奎吴新荣蔡绍晖蒋琳兰孙泽群
Owner 东莞市唐百服生物科技有限公司