Method for preparing dioxidized 4-vinyl cyclohexene
A technology of vinyl cyclohexene and carbon dioxide, which is applied in the direction of organic chemistry, can solve the problems of high cost and low yield of double epoxidation products, and achieve the effects of low energy consumption, simple and fast reaction process, and cost reduction
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Embodiment 1
[0014] In the first step, add 242 ml of 1.775 mol / L sodium hypochlorite solution into a 2000 ml three-neck flask, cool in an ice-water bath, keep the solution temperature at 2-3°C, and add 25 ml of 4-vinylcyclohexene under vigorous stirring. Keep stirring vigorously, add 484 ml of 0.5 mol / L sulfuric acid dropwise, complete the dropwise addition within 40 minutes, continue the reaction for 5 minutes to complete the reaction, and keep the temperature below 10°C during this process.
[0015] In the second step, keep stirring vigorously, the temperature is less than 10°C, add 45 milliliters of 17% NaOH solution to the above-mentioned reaction solution, so that the Ph value of the reaction system is 9, and 20 grams of sodium sulfite solid consumes excessive sodium hypochlorite solution, and the reaction ends in 15 minutes. The product was extracted with 80 ml of dichloromethane.
[0016] In the third step, the yield of 4-vinylcyclohexene dioxide is 36.9% (calculated as 4-vinylcyclo...
Embodiment 2
[0018] In the first step, add 388ml of 1.996mol / L sodium hypochlorite solution into a 2000ml three-neck flask, cool in an ice-water bath, keep the solution temperature at 2-3°C, and add 40ml of 4-vinylcyclohexene under vigorous stirring. Keep stirring vigorously, add 898 ml of 0.5mol / L sulfuric acid dropwise, the dropwise addition is completed within 34 minutes, and continue to react for 5 minutes to complete the reaction. During this process, keep the temperature below 10°C.
[0019] In the second step, keep stirring vigorously, the temperature is less than 10°C, add 64 milliliters of 17% NaOH solution to the above reaction solution, so that the Ph value of the reaction system is 9, 30 grams of sodium sulfite solid consumes excessive sodium hypochlorite solution, and the reaction ends in 15 minutes. The product was extracted with 250 ml of dichloromethane.
[0020] In the third step, the yield of 4-vinylcyclohexene dioxide is 49.2% (calculated as 4-vinylcyclohexene) through G...
Embodiment 3
[0022] In the first step, add 480 ml of 1.76 mol / L sodium hypochlorite solution into a 10,000 ml three-neck flask, cool in an ice-water bath, maintain the solution temperature at 2-3°C, and add 50 ml of 4-vinylcyclohexene under vigorous stirring. Keep stirring vigorously, add 1350 ml of 0.5 mol / L sulfuric acid dropwise, the dropwise addition is completed within 51 minutes, and continue to react for 5 minutes to complete the reaction. During this process, keep the temperature below 10°C.
[0023] In the second step, keep stirring vigorously, the temperature is less than 10°C, add 80 milliliters of 50% NaOH solution to the above-mentioned reaction solution, so that the Ph value of the reaction system is 9.3, 45 grams of sodium sulfite solid consumes excessive sodium hypochlorite solution, and the reaction ends in 30 minutes. The product was extracted with 400 ml of dichloromethane.
[0024] In the third step, the yield of 4-vinylcyclohexene dioxide is 51.6% (calculated as 4-viny...
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