Novel plant capsule film material and method for producing the same

Abstract

The invention provides a novel plant capsule membrane material and a production method thereof. The material comprises the following compositions in weight portion: (A) 0 t0 10 portions of non-gelatin hydrophilic gel; (B) 60 to 94 portions of adhesive; (C) 8 to 18 portions of water; (D) 0 to 5 portions of coagulant aid; and (E) 0 to 10 portions of plasticizer, wherein the adhesive is selected from a composition of pullulan and starch; the weight proportion of the pullulan to the starch is between 1 to 0.1 and 1 to 9.0; and the total weight of the (A), the (B), the (C), the (D), and the (E) accounts for 85 to 100 percent of the total weight of a capsule shell material.

Description

technical field [0001] The invention relates to the field of materials, and more particularly relates to components and production methods of capsule membranes. Background technique [0002] At present, the film of the capsule is made of gelatin extracted from animal bones or skins such as cattle and pigs as raw materials. Although gelatin has excellent properties in the preparation of capsules, gelatin as a heterologous protein may be antigenic. For example, imported bovine-derived gelatin materials may contain prions, and capsules made from them may cause the spread of mad cow disease. In addition, in low moisture or high and low temperature environments, gelatin capsules are easy to deform, stick together or become brittle, and are prone to chemical reactions with aldehyde-based drugs, which is not conducive to drug production: in addition, it is not suitable for vegetarians and gelatin extracted from pig materials is prohibited. The group of people who made the capsule...

AI Technical Summary

Problems solved by technology

[0004] In addition, considering that non-gelatin capsule shell materials are alternative materials for gelatin capsule shells, if the cost is higher than that of gelatin capsule shells, it will be difficult to promote and implement

For example, if pullulan is used as an adhesive, its physical properties are better; but due to its high cost, it is difficult to be popularized and applied

At present, there is a lack of non-gelatin capsule shell materials in the field that have a wide range of raw materials, economical manufacturing costs, possess the required performance of capsules, and are hygienic.