This invention relates to an anti-brittle enteric-coated
gelatin hollow
capsule shell, belonging to the field of hollow
capsule production technology. Addressing the problems of low
mechanical strength, easy breakage during storage and transportation, and increased
brittleness due to high
coating ratios in existing enteric-
coated capsule shells, this invention significantly improves the anti-
brittleness of the
capsule shell while ensuring enteric properties. It utilizes a synergistic compounding of
gelatin, humectants, surfactants, plasticizers, modifiers, disintegrants, opacifiers, and
enteric coating materials, combined with a "step-by-step
coating and online precise temperature-controlled
drying" process. The product meets the
pharmacopoeia's
brittleness requirements for a 20g weight and passes a 100g weight strengthening test. It exhibits
structural stability, low
breakage rate, and is suitable for high-load packaging transportation and long-term storage, making it widely applicable to various enteric-coated
drug formulations.