27 results about "Gelatin capsule" patented technology

The invention discloses opaque capsule shells made from gelatin with ground CaCO3 as opacifier; and a method for making them.

1.The name of the design product: packaging box (lignum aqua gelatin capsule). 2.The use of the design product: for placing medicine or health care products. 3.The design points of the design product: the combination of shape, pattern and color. 4.The picture or photo that best shows the design points: front view. 5.The design contains color.

The utility model discloses a gelatin hollow capsule, which relates to the technical field of hollow capsules and comprises a first capsule cap, a second capsule cap and a fixing device. The second capsule cap is mounted in the first capsule cap in a sliding manner; the fixing device comprises four fixing clamping blocks, a gelatin sealing ring and four positioning blocks, the four fixing clamping blocks are circularly and fixedly connected to the surface of the second capsule cap at equal intervals, the gelatin sealing ring is fixedly connected to the inner wall of the first capsule cap, and the four positioning blocks are circularly and fixedly connected to the inner wall of the first capsule cap at equal intervals; according to the gelatin hollow capsule, when a patient needs to orally take medicine powder in the capsule, the hollow capsule can be rotationally removed, the medicine powder can be extracted without damaging a capsule shell, the gelatin hollow capsule is more convenient to use, and meanwhile the practicability of the gelatin hollow capsule is achieved.

The disclosure generally relates to soft gelatin oral dosage form. In particular the disclosure relates to an oral dosage form comprising a soft gelatin capsule and a liquid fill, where the liquid fill is a suspension of an H2 receptor antagonist in a hydrophobic / lipophilic excipient. The disclosure also relates to a method of treating a gastric disease or disorder by using said oral dosage form.

The invention relates to a soft gelatin capsule. The soft gelatin capsule comprises a capsule shell and filler wrapped by the capsule shell. The capsule shell comprises a low viscosity gelatin having a viscosity of from about 1.5 to about 2.4 mPas and a gel strength of from about 150 to about 280 g Bloom, preferably from about 180 to about 250 g Bloom, in each case as measured in 6.67% gelatin solution at 60 DEG C according to GME-proprietary Standard Test Method for Edible Gelatin.

This utility model discloses a prostaglandin vaginal capsule forming machine, relating to the technical field of capsule forming machines. It includes a support plate, with a slurry forming machine for producing prostaglandin vaginal capsules mounted on the top rear end of the support plate. The slurry forming machine has external auxiliary components for cutting. These auxiliary components include a mounting bracket mounted on the support plate, located at the front of the slurry forming machine. This utility model uses a dual-axis motor to drive a movable bracket, which is limited by a positioning bracket. The movable bracket then drives a cutter to cut the capsule. Because the unloading plate and the cutter move in contact, the slurry adhering to the cutter is pushed off by the unloading plate. Furthermore, because the unloading plate is supported by a telescopic rod and a spring, it can slowly push the slurry, avoiding excessive pressure that could scatter the slurry or hinder subsequent capsule forming. This prevents the slurry from adhering to the outside of the cutter, thus avoiding affecting the feeding efficiency and cutting effect.

The present invention relates to the field of gelatin capsules and in particular to the provision of a gelatin composition for use in the manufacture of gelatin capsules, in particular soft gelatin capsules. The composition of the present invention is particularly useful to reduce cross linking over time in capsules, improving capsule stability.

The present invention relates to a soft gelatin capsule comprising a capsule shell and a filling encased by the capsule shell. The capsule shell comprises a low-viscosity gelatin having a viscosity of about 1.5 to about 2.4 mPa·s and a gel strength of about 150 to about 280 g Bloom, preferably of about 180 to about 250 g Bloom, in each case measured in a 6.67% gelatin solution at 60° C. according to the GME monograph “Standardised Methods for the Testing of Edible Gelatin.”

An orally administered cannabis pill tailored for medicinal and recreational applications and consumption is disclosed. The pill contains decarboxylated cannabis and in some embodiments can include flavoring agents, mineral and vitamin supplements, and Lecithin. The pill is in the form of a gelatin capsule and disintegrates within the human body for providing cannabis advantages without affecting lung health. The invention also includes a method for producing the pill and includes sourcing of fresh and organic cannabis flowers containing cannabinoids. The flowers are subjected to heat and pressure to extract essential oils and produce concentrated cannabis extract discs. Decarboxylation is done to convert THCA into psychoactive THC. Subsequently, the decarboxylated cannabis extract is finely ground into a powder and encapsulated within size 00 gelatin capsules.

The invention provides a traditional Chinese medicine composition with anti-inflammatory and bacteriostatic effects and application thereof, and belongs to the technical field of traditional Chinese medicine compositions. The pharmaceutical composition is prepared from the following components in parts by weight: 3 to 8 parts of baicalin, 24 to 48 parts of chlorogenic acid, 18 to 45 parts of imperatorin and 36 to 80 parts of ferulic acid. The traditional Chinese medicine composition has good anti-inflammatory and bacteriostatic effects, is clear in active ingredient, small in dosage and high in application value, and is suitable for preparing an external medicine for wound surface infection resistance. The composition can be used for preparing traditional Chinese medicine ointment and gel for efficiently and conveniently treating burns and scalds, and has high practical application value.

Provided is a manufacturing device for a gelatin capsule structured to include a pair of medicinal solution supply units configured to supply medicinal solutions being filled in the capsule while adopting most of structures of an existing manufacturing device for a soft capsule. The device is capable of manufacturing capsules where one capsule is charged with medicinal solutions different from each other, or is capable of increasing productivity compared to the existing manufacturing device.

The application discloses a modified gelatin sustained-release capsule and a preparation method and application thereof, and the preparation method of the sustained-release capsule is as follows: S1, calcium magnesium phosphate fertilizer powder is added into deionized water, and stirring is conducted until the water solution is uniform; S2, gelatin particles are mixed with the water solution, and the gelatin particles are absorbed and swelled into gelatin gel; S3, glycerol is added into the gelatin gel, and the gelatin liquid is obtained by stirring and heating; S4, the gelatin liquid is prepared into a capsule film body, the capsule film body is immersed into a crosslinking agent solution for crosslinking; and S5, the crosslinked capsule film body is taken out, and the gelatin capsule is obtained after water drying. The gelatin, water, glycerol and calcium magnesium phosphate fertilizer are uniformly mixed into a solution by heating, and the solution is crosslinked into a shell by glutaraldehyde, and the crosslinking and the filling of the calcium magnesium phosphate fertilizer significantly enhance the mechanical property and the hydrophobic property of the gelatin, and better sustained-release effect is obtained. The fertilizer is packaged into the sustained-release capsule, so that the utilization rate of the fertilizer is improved, and the environment is not polluted.

The invention discloses a double-layer capsule shell controlled release type fish oil soft capsule and a preparation method thereof, and relates to the technical field of fish oil soft capsules. The double-layer capsule shell controlled release type fish oil soft capsule comprises an outer-layer large capsule shell, an inner-layer small capsule shell and a fish oil content wrapped in the inner-layer small capsule shell. Multiple technical breakthroughs are realized through the design of a double-layer structure and a whole polysaccharide system: the outer layer capsule shell constructs an environment barrier, the inner layer realizes targeted controlled release of intestinal tracts, intragastric stimulation of fish oil is avoided from the source, and requirements of special crowds such as infants, postoperative patients and the like are met; the whole polysaccharide raw material replaces gelatin, so that the problem of cross-linking aging is avoided, and long-term disintegration stability and bioavailability of the capsule shell are guaranteed; meanwhile, the auxiliary materials synergistically improve the storage performance, the pain points of gastrointestinal discomfort, storage failure and the like of a traditional single-layer capsule shell and an open capsule shell are effectively solved, the comprehensive performance is remarkably superior to that of a traditional fish oil soft capsule, and the fish oil soft capsule has safety, stability and adaptability to special crowds.

FIELD: pharmaceuticals.SUBSTANCE: relates to a formulation in the form of capsules for oral administration, for immediate release of a native collagen product. A formulation in the form of capsules for oral administration, for immediate release of a native collagen product, which is a gelatin capsule containing a central part, the central part contains a native collagen product from fish skins, ascorbic acid and an anti-caking component – calcium stearate, wt.%: native collagen product 83.08, ascorbic acid 14.96, calcium stearate 1.96.EFFECT: intended for oral administration for immediate release of the native collagen product.1 cl

This invention relates to an anti-brittle enteric-coated gelatin hollow capsule shell, belonging to the field of hollow capsule production technology. Addressing the problems of low mechanical strength, easy breakage during storage and transportation, and increased brittleness due to high coating ratios in existing enteric-coated capsule shells, this invention significantly improves the anti-brittleness of the capsule shell while ensuring enteric properties. It utilizes a synergistic compounding of gelatin, humectants, surfactants, plasticizers, modifiers, disintegrants, opacifiers, and enteric coating materials, combined with a "step-by-step coating and online precise temperature-controlled drying" process. The product meets the pharmacopoeia's brittleness requirements for a 20g weight and passes a 100g weight strengthening test. It exhibits structural stability, low breakage rate, and is suitable for high-load packaging transportation and long-term storage, making it widely applicable to various enteric-coated drug formulations.

The invention relates to a preparation method of a targeting breast cancer stem cell small-molecule inhibitor capsule, and belongs to the technical field of pharmaceutical preparations. The capsule comprises the following components: pipericide, glutathione sensitive poly (disulfide bond)-PEG (SS-PEG), starch, pregelatinized starch, talcum powder and glycerol for plasticizing a capsule shell, the weight percentage of each component is as follows: 25-35% of piperaciliil, 5-10% of SS-PEG, 30-40% of starch, 20-30% of pregelatinized starch and 1-3% of talcum powder; the capsule shell is a No. 0 gelatin capsule and contains 3% (w / w) glycerol as a plasticizer; the average particle size of the nanoparticles in the capsule is 100-200nm, the drug loading capacity is greater than or equal to 85%, and the encapsulation efficiency is greater than or equal to 90%. The capsule prepared by the invention can improve the stability, bioavailability and targeting property of pipericide, so that the inhibition effect on breast cancer stem cells is enhanced, and the treatment effect on breast cancer is improved.

The invention discloses a glucosamine sulfate composition, a capsule as well as a preparation method and application of the glucosamine sulfate composition and the capsule, and belongs to the technical field of pharmaceutical preparations, the glucosamine sulfate composition comprises the following components in percentage by mass: 80-90% of glucosamine sulfate sodium chloride double salt, 3-15% of modified corn starch, 2-6% of lactose and 2-4% of a lubricant. The glucosamine sulfate composition is obtained by compounding and screening auxiliary materials such as modified corn starch and lactose with glucosamine sulfate and sodium chloride double salt, so that the hygroscopicity of the glucosamine sulfate and sodium chloride double salt in a high-humidity environment can be improved, and the problem that water in gelatin capsules is easily reversely absorbed by glucosamine sulfate is solved; the prepared glucosamine sulfate capsule has good disintegration, dissolution rate and stability.

The invention provides a compound dietary nutrient for tonifying qi and blood and a preparation method thereof, and relates to the field of health food. The invention relates to a compound dietary nutrient for tonifying qi and blood and a preparation method thereof. The compound dietary nutrient capable of tonifying qi and blood is prepared from the following raw materials in percentage by mass: 23.9% of plant extract, 22.334% of maltodextrin, 10% of vitamin C, 8% of ferrous glycinate, 6% of fish collagen peptide, 3% of sodium hyaluronate, 1.8% of zinc glycinate, 1% of heme iron, 0.06% of copper gluconate, 0.6% of 2-oxoglutaric acid, 0.2% of vitamin B2, 0.006% of vitamin B12, 0.2% of vitamin B6, 1.4% of vitamin E and the balance of water. 0.3% of pyrroloquinoline quinone disodium salt, 1.2% of silicon dioxide and 20% of gelatin capsules. Through mutual cooperation of the components, the nutrient elements can promote qi and blood of a human body.

The present invention provides a sustained-release capsule of urapidil, comprising sustained-release micropellets and a hollow gelatin capsule shell; the sustained-release micropellets comprise a blank core, a drug-loading layer and a sustained-release layer, and an isolation layer is further provided between the drug-loading layer and the sustained-release layer; the drug-loading layer comprises urapidil API and a binder; the isolation layer is hydroxypropyl methylcellulose and / or hydroxypropyl cellulose; the sustained-release layer comprises a sustained-release material, an enteric material and a pore-forming agent. The urapidil sustained-release capsule of the present invention has a stable API crystal form, the prepared product has good stability, and the dissolution is stable during the accelerated test process, thus solving the problems of API crystal form transformation and low drug loading efficiency during the drug loading process of the drug-loading layer, as well as the problem of rapid dissolution during the stability test of the sustained-release capsule. The present invention also provides a method for preparing urapidil sustained-release capsules, which improves the stability of the preparation by adding an isolation layer and screening a suitable sustained-release layer prescription, thereby ensuring the safety and effectiveness of the drug.

The application discloses a hydroxypropyl starch-based composition, a preparation method and application thereof. The application discloses a preparation method of the composition, which comprises hydroxypropyl starch, polyvinyl alcohol, glycerol, sorbitol, carrageenan, potassium acetate, hydroxypropyl methyl cellulose, dimethicone and water. The composition is used for preparing a hard gelatin capsule shell, and the hard gelatin capsule shell has the advantages of smooth surface, good transparency, high forming rate, low friability, short disintegration time and high stability, and can provide an important reference for replacing traditional gelatin capsules. The preparation method is simple, and the cost is low. The capsule has good apparent properties and forming properties, and has remarkable effects in resisting friability, fast disintegration, storage stability and the like, and has great application prospects in medical preparations, food packaging materials, health product packaging and the like.

The utility model discloses an efficient gelatin capsule drying device which comprises a heat preservation drying cylinder, a rotating motor, a stirring shaft, an air guide channel, a stirring paddle, a heat conduction air hole, an air inlet pump, an electric heater, hot air spraying holes, an open type feeding hopper and a splash-proof net plate. And meanwhile, the gelatin capsules near the stirring paddle are subjected to hot air drying in the process of stirring the gelatin capsules through heat conduction air holes formed in the stirring paddle in a communicating mode, multi-angle and all-directional drying is achieved, the drying effect is uniform, and the drying efficiency is high.

The invention relates to a meclofenoxate hydrochloride capsule. Specifically, the invention provides the meclofenoxate hydrochloride capsule, and the meclofenoxate hydrochloride capsule comprises meclofenoxate hydrochloride and a capsule shell. After the meclofenoxate hydrochloride gelatin capsule and a drying agent are subpackaged in a bottle body together, the meclofenoxate hydrochloride gelatin capsule has excellent stability, and in addition, the meclofenoxate hydrochloride hydroxypropyl methylcellulose capsule also has excellent stability, so that the stability of meclofenoxate hydrochloride in the transportation and storage process is improved, and the quality of the meclofenoxate hydrochloride capsule is improved. And the quality of meclofenoxate hydrochloride is ensured.

The present invention relates to the field of gelatin capsules, and more particularly to providing gelatin compositions for use in the manufacture of gelatin capsules, especially soft gelatin capsules. The compositions of the present invention are particularly useful in reducing crosslinking in capsules over time and improving the stability of the capsules.

The invention discloses a capsule for blood sugar, skeleton and vision triple health intervention for middle-aged and elderly people, and relates to the technical field of health care products. The capsule is composed of a content and a capsule shell, the content takes dietary fiber, calcium element and xanthophyll as core active components, is compounded with synergistic components such as chromium element, vitamin D, zeaxanthin and DHA, and is supplemented with auxiliary materials such as an antioxidant and an emulsifier; the capsule shell is prepared from composite components, so that the stability and compatibility are improved. Triple cooperative intervention of blood sugar regulation, bone strengthening and visual protection is achieved through scientific compounding, the preparation process is optimized, the component stability and bioavailability are ensured, and the problem that existing single or dual-effect products cannot meet multiple health requirements of middle-aged and elderly people is solved.

Soft gelatin capsules comprising a suspension composition of nintedanib or a pharmaceutically acceptable salt thereof in medium chain triglycerides and carrier system, wherein the carrier system comprises solubilizers, phospholipids, thickeners and mixtures thereof.

The high-speed boxing machine comprises a machine frame, a conveying mechanism, positioning mechanisms, a storage box, a material pushing mechanism and an automatic feeding mechanism, the conveying mechanism is installed in the machine frame, the multiple positioning mechanisms are installed on the conveying mechanism and form a left row and a right row on the conveying mechanism, and the material pushing mechanism is installed on the storage box. The left side and the right side of the rack are each provided with a storage box, the upper end of each storage box is provided with a pushing mechanism, and an automatic feeding mechanism is connected between the two storage boxes. Feeding and packaging are carried out from the two sides at the same time, and the working efficiency is higher.