Technique for extracting mixed rhubarb and aconite

A technology of mixed extraction and aconite, which is applied in the field of mixed extraction technology of rhubarb and aconite in the traditional Chinese medicine compound Xiaokening, can solve the problems of many interference factors in the selection of extraction conditions, inability to use traditional Chinese medicine for large-scale production, and ethanol to increase production costs, and the like. Simple, fast extraction rate, and the effect of improving extraction speed
CN101439103AInactive Publication Date: 2009-05-27JIANGSU WANBANG BIOPHARMLS +1

Patent Information

Authority / Receiving Office
CN · China
Patent Type
Applications(China)
Current Assignee / Owner
JIANGSU WANBANG BIOPHARMLS
Publication Date
2009-05-27
Estimated Expiration
Not applicable · inactive patent

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Abstract

The invention relates to the blending extraction process of rhubarb and monkshood in compound Chinese medicine Xiaokening. The blending extraction process of the rhubarb and the monkshood comprises the following steps: mixed powder of the rhubarb and the monkshood is dipped in 6-15 times water for 2-8 hours; and then soak pollution is extracted twice under the assistance of microwave; after extraction liquid is centrifugal and filtered, double extractive supernatant fluids are combined and concentrated till the concentration of drug ingredients is 0.05-0.5g / ml, added with a macroporous resin column for adsorption; firstly, the macroporous resin column is washed with water, and then eluted with ethanol with gradient concentrations; ethanol eluent with 50-80 % of concentration is combined; ethanol is recycled; the blending extractive of the rhubarb and the monkshood is prepared by concentration. The blending extraction process organically combines the microwave assistance extraction process and the macromolecule absorption process and has the technology characteristics of high extraction rate and high purification precision. As the production is safe, reliable, and free from contamination, and the production line composition is simple, the investment is saved.
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Description

technical field

[0001] The invention relates to a mixed extraction process of rhubarb and aconite in the traditional Chinese medicine compound Xiaokening. Background technique

[0002] The traditional Chinese medicine compound Xiao Ke Ning is a combination of three traditional Chinese medicines: Astragalus (Radix Astragli), Rhubarb (Radix et Rhizeoma Rhei) and Aconiti Laterlis Preparata. Among them, astragalus is the main drug, and the ratio of minister drug rhubarb and aconite is 1:1.

[0003] Rhubarb (Radix et Rhizeoma Rhei) is the dry root and rhizome of Rheum palmatum L., Rheum tangguticm Maxim.ex Balf. or Rheum officinale Bail. of Polygonaceae. Mainly produced in Gansu, Qinghai and other places. Bitter in nature, cold, slightly poisonous. Rhubarb has the effects of purging and attacking stagnation, clearing heat and purging fire, promoting blood circulation and removing stasis, and detoxifying. It is used for constipation, gastrointestinal stagnation, blood heat and...

Claims

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