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Application of traditional Chinese medicine composition in preparing medicament of insulin sensitizer

A composition and technology of traditional Chinese medicine, applied in the application field of preparing angiotensin-converting enzyme inhibitor drugs, can solve undisclosed problems, and achieve the effects of safe and convenient use, improvement of insulin resistance, and good insulin sensitization effect

Inactive Publication Date: 2009-11-25
HEBEI YILING MEDICINE INST
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

The above-mentioned patent does not disclose the application of the traditional Chinese medicine composition in the preparation of insulin sensitizer drugs and the preparation of angiotensin-converting enzyme inhibitor drugs. Application of traditional Chinese medicine composition in preparation of above-mentioned medicine

Method used

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  • Application of traditional Chinese medicine composition in preparing medicament of insulin sensitizer

Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0048] The raw material drug formula is:

[0049] Ginseng 102g, Polygonatum 136g, Atractylodes 68g, Sophora flavescens 56g, Poria cocos 83g, Ophiopogon japonicus 136g, Polygonum multiflorum 83g, Rehmannia glutinosa 102g, Cornus officinalis 136g, Coptis 56g, Peilan 56g, Lychee seed 136g, Epimedium 56g, Anemarrhena 68g, Salvia miltiorrhiza 89g, Pueraria 136g, Digupi 83g.

[0050] The preparation method is:

[0051] a. Weigh Chinese medicinal materials according to the prescription amount, cleanly select and break;

[0052] b. Add 6 times the amount of water to Peilan and Cangzhu to extract the volatile oil. The oil extraction time is 5 hours. The volatile oil is collected in another device, and the aqueous solution is filtered for later use, and the residue is discarded;

[0053] c. Cornus officinalis is impregnated with 7 times the amount of 75% ethanol for 24 hours, then percolated, the percolated liquid is collected, the ethanol is recovered, and concentrated into a thick p...

Embodiment 2

[0059] The raw material drug formula is:

[0060] Ginseng 42g, Polygonatum 200g, Atractylodes 30g, Sophora flavescens 60g, Poria cocos 35g, Ophiopogon japonicus 200g, Polygonum multiflorum 35g, Rehmannia glutinosa 120g, Cornus officinalis 50g, Coptis 60g, Peilan 30g, Lychee seed 150g, Epimedium 30g, Anemarrhena 100g, Salvia miltiorrhiza 35g, Pueraria 200g, Digupi 30g.

[0061] The preparation method is:

[0062] a. Weigh Chinese herbal medicines according to the prescription amount, cleanly select and break them;

[0063] b. Add 5 times the amount of water to Peilan and Cangzhu to extract the volatile oil. The oil extraction time is 3 hours. The volatile oil is collected in another device, and the aqueous solution is filtered for later use, and the residue is discarded;

[0064] c. After impregnating Cornus officinalis with 5 times the amount of 50% ethanol for 12 hours, carry out percolation, collect the percolation liquid, recover ethanol, and concentrate it into a thick p...

Embodiment 3

[0070] The raw material drug formula is:

[0071] Ginseng 160g, Polygonatum 50g, Atractylodes 100g, Sophora flavescens 20g, Poria cocos 100g, Ophiopogon japonicus 50g, Polygonum multiflorum 100g, Rehmannia glutinosa 50g, Cornus officinalis 200g, Coptidis 20g, Perrin 60g, Lychee seed 75g, Epimedium 60g, Anemarrhena 30g, Salvia miltiorrhiza 120g, Pueraria 50g, Digupi 100g.

[0072] The preparation method is:

[0073] a. Weigh Chinese herbal medicines according to the prescription amount, cleanly select and break them;

[0074] b. Add 9 times the amount of water to Peilan and Cangzhu to extract the volatile oil. The oil extraction time is 6 hours. The volatile oil is collected in another device, and the aqueous solution is filtered for later use, and the residue is discarded;

[0075] c. Cornus officinalis is soaked with 9 times the amount of 90% ethanol for 48 hours, then percolated, the percolated liquid is collected, the ethanol is recovered, and concentrated into a thick pa...

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Abstract

The invention discloses application of a traditional Chinese medicine composition in preparing a medicament of an insulin sensitizer and in preparing a medicament of an angiotensin converting enzyme inhibitor. The traditional Chinese medicine composition consists of 17 kinds of traditional Chinese medicines of ginseng, rhizoma polygonati, rhizoma atractylodis, radix sophorae falvescentis and the like. Through benefiting vital energy and nourishing Yin, invigorating spleen and promoting body fluid, the invention can not only effectively improve and treat insulin resistance of II-type diabetes mellitus for treating II-type diabetes mellitus suitably, but also can effectively restrain activity of angiotensin converting enzyme for treating hypertension with obvious effect.

Description

technical field [0001] The present invention relates to a new application of a traditional Chinese medicine composition, in particular, relates to the application of a traditional Chinese medicine composition in the preparation of insulin sensitizer drugs, and at the same time discloses the use of the traditional Chinese medicine composition in the preparation of angiotensin-converting enzyme inhibitory The application in medicinal preparations belongs to the application field of traditional Chinese medicine. Background technique [0002] With the rapid development of social economy and changes in lifestyle, the incidence of metabolic syndrome (MS) has increased sharply. Its diagnosis and treatment involve many disciplines such as endocrinology and cardiovascular, and it has become a new health hotspot. MS represents the aggregated state of a series of cardiovascular disease risk factors, including obesity, hypertension, abnormal blood sugar, atherosclerotic dyslipidemia and...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): A61K36/8969A61K9/00A61K9/16A61P5/50A61P9/04A61P9/12A61P13/12
Inventor 李向军安军永王超郑立发
Owner HEBEI YILING MEDICINE INST
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