Preparation method and product of biomedical porous implantation body

A technology for biomedical and implants, which is applied in the field of preparation of porous biomedical implants, can solve the problems of decreased mechanical properties of implants, unfavorable formation of mineralized bone, etc., and achieve controllable porosity and prolong service life Effect

Inactive Publication Date: 2010-01-06
BEIJING SMART TECH
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

[0005] In order to solve the problem that the existing biomedical porous implant technology has a decline in the mechanical properties of the implant and is not conducive to the formation of mineralized bone in the implant, the present invention provides a preparation method for the biomedical porous implant. It can effectively control the porosity, pore size and connection between pores of the porous implant, so as to not only ensure the mechanical properties of the implant but also facilitate the formation of mineralized bone in the implant.

Method used

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  • Preparation method and product of biomedical porous implantation body
  • Preparation method and product of biomedical porous implantation body
  • Preparation method and product of biomedical porous implantation body

Examples

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Effect test

example 1

[0040] Take a nickel-titanium alloy wire with a diameter of 0.1mm and a mass ratio of titanium to nickel of 40:60, wind it into a helical wire with a pitch of 1mm and a diameter of 1mm to form a basic unit, and lay the basic units vertically to form a single-layer porous The net-like sheet is tightly curled to form a net-like structure, and then the net-like structure is put into a mold and pressed to become a rough implant body. In this embodiment, the pressure applied during pressing is 20 MPa, and the pressing time is 10 minutes.

[0041] At 20°C, the rough implant body was ultrasonically cleaned with a mixed solvent of acetone and absolute ethanol with a mixing volume ratio of 1:1 for 20 minutes, and then treated with a mixed acid for 20 minutes. The mixed acid volume ratio was HF:HNO 3 :H 2 O=1:2:3, followed by washing with deionized water. This is a routine surface cleaning step to remove impurities from the surface of the alloy wire.

[0042] Then the rough implant b...

example 2

[0046] Take a nickel-titanium alloy wire with a diameter of 0.1 mm and a mass ratio of titanium to nickel of 45:55, fold it into a sawtooth structure with a tooth pitch of 1 mm and a tooth height of 1 mm to form a basic unit, and lay the basic units vertically to form a single-layer porous structure. The net-like sheet is tightly curled to form a net-like structure, and the net-like structure is put into a mold, and the rough blank of the implant is taken out after compression molding. In this embodiment, the pressure applied during pressing is 25 MPa, and the pressing time is 5 minutes.

[0047] At 35°C, the rough implant body was ultrasonically cleaned with a mixed solvent of acetone and absolute ethanol with a mixing volume ratio of 1:1 for 22 minutes, and then treated with a mixed acid for 40 minutes. The mixed acid volume ratio was HF:HNO 3 :H 2 O=1:2:3, followed by washing with deionized water.

[0048] Then the rough implant body is vacuumed at 1200°C (vacuum degree i...

example 3

[0050] Take a nickel-titanium alloy wire with a diameter of 0.1mm and a mass ratio of titanium to nickel of 45:55, weave it into a mesh tube with a diameter of 1mm to form a basic unit, and arrange the basic units vertically to form a single-layer porous mesh sheet, and then Tightly curl the single-layer porous mesh sheet to form a mesh structure, put the mesh structure into a mold, and take out the rough blank of the implant after compression molding. The pressure applied in this embodiment is 30 MPa, and the pressing time is 8 minutes.

[0051] At 50°C, the rough implant body was ultrasonically cleaned with a mixed solvent of acetone and absolute ethanol with a mixing volume ratio of 1:1 for 27 minutes, and then treated with a mixed acid for 50 minutes. The mixed acid volume ratio was HF:HNO 3 :H 2 O=1:2:3, followed by washing with deionized water.

[0052] Then the rough implant body is vacuumed at 1250°C (vacuum degree is 1.0×10 -3 Pa) under sintering for 2 hours, the f...

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Abstract

Aiming to solve the problems that the mechanical property of the implant is reduced and that the mineralization bone is not easily formed in the implant existing in the technology for preparing the biomedical porous implant, the invention provides a biomedical porous implant and a method for preparing the same. The method comprises the following steps of: interweaving threads of the implant material to form a netty structure; pressing the netty structure into an implant coarse blank with a special shape; sintering the implant coarse blank so as to allow the material threads at cross points in the netty structure to form melting connection to prepare the implant. The plantation body prepared by the method can be used for preparing biomedical porous nickel-titanium alloy implants such as denda, artificial joints and the like and realizing the deep freezing treatment of hemangioma, ecphymata and keloid by carrying liquid nitrogen.

Description

technical field [0001] The invention relates to a biomedical implant technology, in particular to the preparation technology of a porous biomedical implant. Background technique [0002] In the field of biomedicine, alloy materials are often used to make implants, and alloy materials are often selected to have good biocompatibility and other characteristics, such as nickel-titanium alloys that are widely used. The microstructure of existing biomedical implants is a porous structure, that is, the implant itself has many tiny interconnected pores. Due to the existence of this porous structure, the implant itself has a certain space for elastic changes, so that the mechanical properties of the implant itself match with the surrounding biological environment such as natural bone. In addition, when the pore diameter of the porous structure is greater than 0.1mm, and the internal connection pore diameter (the size of the connecting channel between the pores) is greater than 0.05m...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): A61F2/02A61L27/04A61L27/06A61L31/02
Inventor 郑玉峰黄兵民
Owner BEIJING SMART TECH
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