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Pharmaceutical composition for treating ulcus cruris and preparation method thereof

A technology of composition and medicine, which is applied in the field of pharmaceutical composition and its preparation, can solve the problems of convenient administration, rapid onset of effect, comfortable medication, pain and stimulation of preparations, and susceptibility to infection, which are difficult to adapt to surgery, so as to promote healing and recovery, reduce Painful, fast-acting effects

Inactive Publication Date: 2010-02-17
安徽省华鼎生物科技有限公司
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

Traditional Chinese medicine preparations for external use, such as powder, lotion, plaster, patch, ointment, ointment, etc., have achieved good curative effect in clinical application, but the existing preparations still have pain stimulation, easy infection, and easy retention. Defects such as scars and inconvenient medication are difficult to adapt to the requirements of convenient surgical administration, rapid onset of effect, accelerated healing, no scars, and comfortable medication, which limits its clinical promotion and application

Method used

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  • Pharmaceutical composition for treating ulcus cruris and preparation method thereof

Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0065] Licorice 60g Angelica 60g Angelica 60g

[0066] Comfrey 60g, dried blood 24g, collagen 100g

[0067] Take licorice, angelica, angelica, and comfrey, boil them twice with water, filter, combine the filtrates, concentrate to a concentrated solution with a relative density of 1.16 at 60°C, add ethanol to make the alcohol content reach 80%, and let it stand for 24 hours in refrigeration. Filtrate, recover ethanol, concentrate to a concentrated solution with a relative density of 1.14 at 60°C; take dried blood and dissolve it in 50ml of absolute ethanol, filter, and use the filtrate for later use; take collagen, dissolve it in distilled water, add 10g of carbomer, and swell After 24 hours, add the above raw material drug extract, 10ml of propylene glycol, 10g of azone, add water to 1000g, mix evenly, and make a gel.

Embodiment 2

[0069] Licorice 80g Angelica 80g Angelica 80g

[0070] Comfrey 80g Drain 34g Collagen 150g

[0071] Take licorice, angelica, angelica, and comfrey, extract them twice with 50% ethanol, filter, combine the filtrates, recover the ethanol, and concentrate to a concentrated solution with a relative density of 1.18 at 60°C; Take the collagen, dissolve it with distilled water, add chitosan 5g, dissolve, add the above-mentioned crude drug extract, Tween 80 10ml, add water to 1000g, mix evenly, fill, and make a spray.

Embodiment 3

[0073] Licorice 90g Angelica 90g Angelica 90g

[0074] Comfrey 90g, dried blood 40g, collagen 80g

[0075] Take licorice, angelica, angelica, and comfrey, decoct them twice with water, filter, combine the filtrates, concentrate to a concentrated solution with a relative density of 1.13 at 60°C, add ethanol to make the alcohol content reach 80%, and let it stand for 24 hours in refrigeration. Filtrate, recover ethanol, concentrate to a concentrated solution with a relative density of 1.12 at 60°C; take dried blood and dissolve it in 50ml of absolute ethanol, filter, and use the filtrate for later use; take collagen, add water to swell for 24 hours, add 1g of azone, dissolve, Add raw material drug extract, add water to 1000g, mix evenly, add dressing to make wet compress.

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Abstract

The invention discloses a pharmaceutical composition for treating ulcus cruris and a preparation method thereof, which belong to the field of Chinese medicaments. The pharmaceutical composition is characterized in that a corresponding preparation is prepared from liquoric root, dahurian angelica root, Chinese angelica, sinkiang arnebia root, dragon's blood and collagen in a certain proportion by extracting and refining, and adding auxiliary materials of the preparation according to the conventional method. The pharmaceutical composition has good treatment effects on diabetic foot and ulcus cruris.

Description

technical field [0001] The invention relates to a pharmaceutical composition and a preparation method thereof, in particular to a traditional Chinese medicine composition for treating diabetic foot and chronic lower extremity ulcer, belonging to the field of traditional Chinese medicine. Background technique [0002] Diabetic foot and chronic lower extremity ulcers in TCM surgical diseases are characterized by skin damage or ulcers. Because these diseases often cause skin surface defects, resulting in deep dermis or deeper skin damage, often lingering and difficult to heal, the course of the disease is long. A refractory disease recognized by doctors. The external treatment method of traditional Chinese medicine emphasizes that "surgical treatment should focus on external treatment" and "the key to external treatment should be 'removing putrefaction and promoting muscle growth'", which should not only achieve the effect of antibacterial, anti-inflammatory, blood circulation ...

Claims

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Application Information

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IPC IPC(8): A61K38/39A61K9/00A61K9/12A61P17/02A61K36/889
Inventor 代龙
Owner 安徽省华鼎生物科技有限公司
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