Pharmaceutical composition for treating ulcus cruris and preparation method thereof

A technology of composition and medicine, which is applied in the field of pharmaceutical composition and its preparation, can solve the problems of convenient administration, rapid onset of effect, comfortable medication, pain and stimulation of preparations, and susceptibility to infection, which are difficult to adapt to surgery, so as to promote healing and recovery, reduce Painful, fast-acting effects

Inactive Publication Date: 2010-02-17
安徽省华鼎生物科技有限公司
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

Traditional Chinese medicine preparations for external use, such as powder, lotion, plaster, patch, ointment, ointment, etc., have achieved good curative effect in clinical application, but the existing preparations still have pain stimulation, easy infection, and easy ret

Method used

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  • Pharmaceutical composition for treating ulcus cruris and preparation method thereof

Examples

Experimental program
Comparison scheme
Effect test

Example Embodiment

[0064] Example 1

[0065] Licorice 60g Angelica root 60g Angelica 60g

[0066] Lithospermum 60g Dragon's Blood 24g Collagen 100g

[0067] Take licorice, angelica, angelica, comfrey, decoct it twice with water, filter, combine the filtrate, concentrate to a concentrated solution with a relative density of 60°C of 1.16, add ethanol to make the alcohol content 80%, and let it stand for 24 hours. Filter, recover ethanol, and concentrate to a concentrated solution with a relative density of 60°C of 1.14; Dissolve the dragon's blood with 50ml absolute ethanol, filter, and use the filtrate for use; take collagen, dissolve it with distilled water, add 10g carbomer, and swell For 24 hours, add the above-mentioned crude drug extract, 10ml of propylene glycol, 10g of azone, add water to 1000g, mix evenly, and make a gel.

Example Embodiment

[0068] Example 2

[0069] Licorice 80g Angelica root 80g Angelica 80g

[0070] Lithospermum 80g, dried up 34g, 150g collagen

[0071] Take licorice, angelica, angelica, comfrey, extract twice with 50% ethanol, filter, combine the filtrate, recover the ethanol, and concentrate to a concentrated solution with a relative density of 60°C of 1.18; take the dragon's blood and dissolve it with 50ml absolute ethanol, filter After passing, the filtrate is ready for use; take collagen, dissolve it in distilled water, add 5g of chitosan, dissolve it, add 10ml of the above-mentioned crude drug extract, Tween 80, add water to 1000g, mix well, fill, and make a spray.

Example Embodiment

[0072] Example 3

[0073] Licorice 90g Angelica root 90g Angelica 90g

[0074] Lithospermum 90g Dragon's Blood 40g Collagen 80g

[0075] Take licorice, angelica, angelica, comfrey, decoct twice with water, filter, combine the filtrate, and concentrate to a concentrated solution with a relative density of 60°C of 1.13, add ethanol to make the alcohol content 80%, and let it stand for 24 hours. Filter, recover ethanol, and concentrate to a concentrated solution with a relative density of 60°C of 1.12; Dissolve the dragon's blood with 50ml absolute ethanol, filter, and use the filtrate for use; take collagen, add water to swell for 24 hours, add 1g of azone, and dissolve it. Add the crude drug extract, add water to 1000g, mix evenly, add dressing to make a wet compress.

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Abstract

The invention discloses a pharmaceutical composition for treating ulcus cruris and a preparation method thereof, which belong to the field of Chinese medicaments. The pharmaceutical composition is characterized in that a corresponding preparation is prepared from liquoric root, dahurian angelica root, Chinese angelica, sinkiang arnebia root, dragon's blood and collagen in a certain proportion by extracting and refining, and adding auxiliary materials of the preparation according to the conventional method. The pharmaceutical composition has good treatment effects on diabetic foot and ulcus cruris.

Description

technical field [0001] The invention relates to a pharmaceutical composition and a preparation method thereof, in particular to a traditional Chinese medicine composition for treating diabetic foot and chronic lower extremity ulcer, belonging to the field of traditional Chinese medicine. Background technique [0002] Diabetic foot and chronic lower extremity ulcers in TCM surgical diseases are characterized by skin damage or ulcers. Because these diseases often cause skin surface defects, resulting in deep dermis or deeper skin damage, often lingering and difficult to heal, the course of the disease is long. A refractory disease recognized by doctors. The external treatment method of traditional Chinese medicine emphasizes that "surgical treatment should focus on external treatment" and "the key to external treatment should be 'removing putrefaction and promoting muscle growth'", which should not only achieve the effect of antibacterial, anti-inflammatory, blood circulation ...

Claims

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Application Information

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IPC IPC(8): A61K38/39A61K9/00A61K9/12A61P17/02A61K36/889
Inventor 代龙
Owner 安徽省华鼎生物科技有限公司
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