71results about How to "Reduce the number of dressing changes" patented technology

The invention relates to washable negative pressure drainage dressing which comprises a sponge body, a drainage catheter and a washing catheter, wherein a double-cavity catheter is inserted in the sponge body, a plurality of through holes are evenly arranged on the wall of the double-cavity catheter inserted in the sponge body, and the outer end of the double-cavity catheter is connected with the drainage catheter and the washing catheter through a tee joint. A washing cavity channel and a drainage cavity channel are arranged in the double-cavity catheter. According to the washable negative pressure drainage dressing, the medical sponge body can be repeatedly washed in the treatment process, so that phenomena such as unsmooth drainage caused by drying and blocking of the sponge body in the wound negative pressure treating process are avoided. The washable negative pressure drainage dressing is reasonable in structure and convenient to operate and use, and reduces dressing change times and risk of clinical infection. In addition, the clinical operation is safe and convenient.

The invention provides a 3D-printing wound dressing material based on silk microsphere bio-ink and a preparation method thereof. The preparation method includes the following steps: transferring silkmicrosphere bio-ink, which includes silk protein microspheres coating aspirin, silk protein water solution, ultraviolet initiator and polyvinyl alcohol ester, into a syringe of a 3D-printing machine;with a cotton gauze as a base printing cloth, printing the surface of the cotton gauze with the silk microsphere bio-ink according to a periodically circulated cross-network structure model; and rapidly curing and shaping the 3D-printing wound dressing material under ultraviolet irradiation. The product is based on 3D-printing technology, wherein the formed cross-network structure contains regularly arranged silk microspheres, and the silk microsphere bio-ink coating layer cures on the surface of the cotton gauze and does not completely penetrate through the cotton gauze. The 3D-printing wounddressing material has good mechanical performance and biocompatibility and excellent slow-release performance, can protect a wound for a long time and can accelerate healing of the wounding.

The invention relates to a controlled-release antibacterial dressing and a preparation method thereof and particularly discloses a compound. The compound contains a dressing carrier and microspheres loaded to the dressing carrier. The invention further discloses a composition, a dressing as well as a preparation method and use of the dressing. According to the composition and the dressing, the pharmaceutical burst release phenomenon of a common antibacterial dressing can be effectively improved, and the growth and reproduction of germs such as escherichia coli, staphylococcus aureus, pseudomonas aeruginosa and Candida albicans can be steadily inhibited for a long time. The controlled-release antibacterial dressing provided by the invention is applicable to the treatment of operation cuts,wounds, burns, donor sites, pressure sores, diabetic ulcer and other wound surfaces.

The invention belongs to the field of medical materials and particularly relates to a functional wound surface repairing material and a preparation method thereof. The wound surface repairing material is prepared by compounding 7-14 parts of bioactive glass, 0.5-0.7 part of silver nitrate, 0.2-0.6 part of antibiotics, 15-25 parts of degradable polymer and 80-160 parts of deionized water. The functional wound surface repairing material is loaded with silver ions and antibiotics, wherein the silver ions and the antibiotics respectively have bactericidal performance, and the silver ions can enable the antibiotics to more easily enter bacteria to exert synergistic action by increasing the generation of oxygen free radicals and increasing the permeability of bacterial membranes, so that the functional wound surface repairing material has relatively strong antibacterial performance and can solve the problem that bacteria are easy to adhere to the existing wound surface repairing material to cause infection and then the curative effect is not ideal.

The invention relates to a medicinal chitosan dressing which comprises the constituents of (by weight parts) chitosan 5-10, polyvinyl alcohol 6-15, gelatin 5-10, glycerol 10-20, water 45-75, and the preparing process consists of swelling with water, dissolving through water-bath, mixing solutions homogenously, adjusting pH to 4-7, filtering and removing foams.

The invention discloses a heparin derivative-poloxamer temperature sensitive hydrogel and a preparation method thereof. The poloxamer is used as a framework material, and N-Acetylated low molecular weight heparin and prednisone are compounded to obtain the hydrogel. The mass ratio of the N-Acetylated low molecular weight heparin to the poloxamer is 15-90:100-300. The preparation method comprises the following steps that step 1, the N-Acetylated low molecular weight heparin is weighed and placed in a serum bottle, and a PBS buffer solution is added; step 2, a prednisone drug PBS buffer solutionwith mass concentration of 5% is added, stirring at the room temperature is conducted and lasts for 12-36 hours; and step3, the poloxamer is weighed, and the solution in the step 2 is added, solutionstirring is conducted at 4-10 DEG C and last for 12-36 hours. The heparin derivative-poloxamer temperature sensitive hydrogel has the excellent effect, is long in antibacterial time, and has simple procedures; and industrialization can be achieved easily, and popularization and application are facilitated.

The present invention relates to a kind of compound artificial skin with two kinds of cells implanted on its two sides and its construction process. On two sides of rack of ox collagen membrane with epidermal growth factor, fibroblast and epidermal cell are implanted, and the middle part is growing fibroblast of density grater than 1E6/sq cm. The artificial skin has excellent physical characteristics, high strength, high flexibility, high infection resistance, no antigenicity, convenient operation transplantation and good fusion with peripheral skin after transplantation.

The invention discloses a medical dressing for treating a large area wound and a manufacturing method thereof. The medical dressing is composed of from top to bottom: an isolation paper, a sodium alginate hydrogel, a non-woven fabric, a medical glue layer and a base cloth; or from top to bottom, an isolation paper, an alginate hydrogel, a medical glue layer and a base cloth. The sodium alginate hydrogel is a hydrogel mixed by 100 percent pure sodium alginate crystals and water. The alginate hydrogel is a hydrogel, which assumes a transparent gel shape formed by immersing a 100 percent pure calcium alginate non-woven fabric to a sodium alginate solution, automatically converts between a solid state and a liquid state based on changes of using state. The novelty of the invention lies in combining a material which promotes curing of the wound and a material which is secured to body surface. The medical dressing of the invention has the advantages of outside water resistance, extra-long adhering time, and simple operation and usage. The medical dressing of the invention faces towards the wound in humid environment, which promotes healing. The medical dressing can also reduce burning pain caused by the large area wound, prevent infection and wound adhesion, block bacteria from entering, and reduce times for changing medicine.

The invention relates to a medicine composition for clinical care of burns and a preparation method thereof. The medicine composition is formed by the following raw materials by weight: 25 parts of mimosa pudica, 12 parts of lithospermum, 10 parts of polygonum cuspidatum, 10 parts of radix angelicae, 6 parts of gardenia, 35 parts of coptis chinensis, 30 parts of syzygium aromaticum, 15 parts of honeysuckle, 30 parts of scutellaria baicalensis, 30 parts of angelica sinensis, 12 parts of myrrh, 6 parts of rhizoma atractylodis, 10 parts of garden burnet, 12 parts of gallnut, 10 parts of pearl, 6parts of smoked plum, 10 parts of calamine, 2 parts of pseudo-ginseng, 8 parts of gypsum rubrum, 5 parts of divaricate saposhnikovia roots, 10 parts of white backleaf mallotus roots, 6 parts of radixampelopsis, 8 parts of frankincense and 10 parts of dragon's blood. The medicine composition for the clinical care of burns has low cost and remarkable curative effect, leaves no scars after curing and has broad application prospects.

The invention relates to a traditional Chinese medicinal composition for treating burns and scalds and a preparation method thereof. The composition is characterized in that the composition is prepared from the following raw material components, by weight, 1-90 parts of gypsum, 26-100 parts of stalactite, 1-100 parts of Boswellia carteri, 31-70 parts of myrrh, 27-90 parts of Rheum officinale and 30-100 parts of catechu or Radix Sanguisorbae. The preparation method comprises the following steps: 1, cleaning the raw material components according to above weight parts; 2, respectively grinding them into powders after air drying; 3, mixing the powders; 4, adding sesame oil having a weight 1-100 times of raw material components to the obtained powdery product; and 5, stirring to obtain a pastyproduct. According to the traditional Chinese medicinal composition, the cure period to the burns and the scalds is short, first degree burns or scalds can be healed after 3-5 days, second degree burns or scalds can be healed after 6-7 days, and third degree burns or scalds can be healed after about half a month. The composition is replaced by a patient 1-2 times each day, so convenience is provided for the patient. In addition, the cure rate of the composition reaches 100%.

The invention relates to a drug loaded amnion sheet and a preparation method and applications thereof. Specifically, the drug loaded amnion sheet comprises a dry amnion and following components, which are loaded on the dry amnion and substrate membrane surface of amnion, in parts by weight: 5 to 30 parts of bletilla striata, 10 to 30 parts of calcined gypsum, 3 to 25 parts of frankincense, 3 to 25 parts of myrrh, 10 to 30 parts of rhizoma atractylodis, 0.5 to 5 parts of artificial musk, 1 to 15 parts of borneol, and 2 to 30 parts of safflower. The invention also discloses a preparation method of the drug loaded amnion sheet and an application of the drug loaded amnion sheet in the preparation of a medical material for treating skin ulcer diseases. The rapid release and slow release functions of the drug loaded amnion sheet are combined, and the drug loaded amnion sheet can sustain an effective drug concentration in the local environment of wounds.

The invention discloses an anus lotion, which is prepared from the following raw materials by weight: 25-35g of radix sophorae flavescentis, 15-25g of cortex phellodendri, 10-20g of radix aconiti preparata, 10-20g of prepared kusnezoff monkshood root, 15-25g of radix angelicae, 25-35g of stephania terandra, 25-35g of dittany bark, 8-12g of dried alum, 12-18g of rheum officinale and 15-25g of gallnut in a manner of decocting after adding water. The anus lotion has the beneficial effects that the anus lotion has the main characteristics of convenience for use and wide pharmacological action, and simultaneously can treat anus diseases with a plurality of concurrent symptoms such as bleeding, pain, pruritus, secretion increase and the like. Clinical application finds that most of haemorrhoids can retract and dissipate as to internal hemorrhoids, inflammatory external hemorrhoids, external hemorrhoids and mixed hemorrhoids at each stage after a patient takes the anus lotion for 5-7 days. Anal eczema can scab and heal after the anus lotion is used for 1-2 weeks while the symptoms are obviously relieved after the patients with anus itching, condyloma acuminata and anal fissure take the anus lotion. Especially for the patient with an anus operation, the anus lotion can relieve swelling and pain, also can purify the wound, reduces the frequency of dressing change, and obviously shortens the wound healing time.

The invention relates to a protection product for preventing and treating electric employee electric burn and fire burn. The protection product is prepared from common andrographis herb, Corydalis bungeana Turcz., sappan wood, safflower, bletilla striata, arnebia root, garden burnet, white peony root, frankincense, dragon's blood, cortex lycii radicis, aloe, arctium fruit, radix ophiopogonis, spatholobus stem, rhizoma corydalis, radix angelicae sinensis, ligusticum wallichii, coptis root, herba schizonepetae, cordate houttuynia, radix astragali, divaricate saposhnikovia root, dandelion and honeysuckle flower. Active ingredients of the above traditional Chinese medicines are extracted, the extract and sesame oil are mixed and processed to form paste and the paste is spread on gauze. The protection product has substantial effects on electric burn and fire burn and has a wide application prospect.

The invention relates to an ointment for burns and scalds, made from the medicinal materials: Rhizoma Polygoni Cuspidati, Radix Arnebiae seu Lithospermi, Poria, Stigma Croci Sattvi, Galla Chinensis, Radix Glycyrrhizae, Herba Violae, Fructus Forsythiae, Herba Patriniae, Herba Houttuyniae, Herba Scutellariae Barbatae, Herba Taraxaci, Herba Hedyotis Diffusae, Pseudobulbus Cremastrae seu Pleiones, Rhizoma Paridis, Cacumen Platycladi, Fructus Gardeniae, Radix Angelicae Dahuricae, Cortex Phellodendri, Herba Artemisiae Anomalae, Rhizoma Bletillae, Folium Artemisiae Argyi, Cortex Moutan Radicis, Radix Paeoniae Rubra, Rhizoma Rehmanniae Preparata, Radix Notoginseng, Rhizoma Atractylodis Macrocephalae, Flos Carthami, Rhizoma Chuanxiong, Semen Vaccariae, Herba Lycopodii, and Fructus Tribuli. The ointment is prepared by pulverizing and screening effective medicinal ingredients. The ointment is effective in clearing heat and drying dampness, subsiding swelling and relieving pain, and activating blood and dredging channels, has significant effect for treating burns and scalds and has a promising application prospect.

The invention provides a preparation method of a medical dressing, which includes preparation of secreted PLGA sustained-release microspheres, preparation of a hydrogel, preparation of an electrospunmembrane, and preparation of a stem cell secretion medical dressing. In the invention, a combination of sub-totipotent stem cell secretin, PLGA sustained-release microspheres and hyaluronic acid hydrogel is used, and the electrospun membrane is used as a carrier to prepare the medical dressing, the sub-totipotent stem cell secretion is rich in various active factors, and has a good repair effect on wounds; Experiments show that the medical dressing prepared by the invention has a good healing effect on both acute and chronic wounds. The medical dressing can adhere to the wound well, and the sub-totipotent stem cell secretin in the PLGA sustained-release microspheres is slowly released, which greatly improves the utilization rate of the secretion and the durability, the PLGA slow-release microspheres contain a larger amount of subtotipotent stem cell secretions, which reduces the number of dressing changes, avoids secondary trauma during the dressing change, and facilitates wound repair.