Traditional Chinese medicine biological agent for improving immunity of livestock and preparation method thereof

A technology for biological preparations and immunity, applied in biochemical equipment and methods, microorganism-based methods, microorganisms, etc., can solve the problems of disproportionate development of animal husbandry, low bioavailability, and low technical content, and improve livestock and poultry. Immunity and production performance, low bioavailability, dose reduction effect

Active Publication Date: 2010-04-07
BEIJING DABEINONG ANIMAL HEALTH TECH
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  • Abstract
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  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

However, the Chinese herbal immune enhancers currently used are generally powders with low technical content, which are directly added to t

Method used

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  • Traditional Chinese medicine biological agent for improving immunity of livestock and preparation method thereof
  • Traditional Chinese medicine biological agent for improving immunity of livestock and preparation method thereof

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[0028] Example 1 Preparation of traditional Chinese medicine biological preparation of the present invention

[0029] Chinese medicine composition: 100 parts of Eucommia leaves, 100 parts of Grifola frondosa, 50 parts of Astragalus, 50 parts of Epimedium Preparation method:

[0030] (1) Inoculate Bacillus into common broth medium, culture at 37℃, 220rpm shaker to produce first-level seed liquid, when the content of viable bacteria reaches 1.0×10 8~9 When cfu / ml, transfer to the secondary seed liquid fermentor to expand the culture, the inoculum amount is 10%, the culture temperature is 30℃, the stirring speed is 220rpm, and the viable bacteria content of the secondary seed liquid reaches 1.0×10 8~9 When cfu / ml, stop the culture and reserve;

[0031] (2) Take the prescription amount of Chinese medicinal materials, pulverize them into 120 mesh medicinal powder, put them into the fermenter, add 20% bran, 10% soybean meal, 0.6% ammonium sulfate, 0.05% magnesium sulfate, 0.02% by weight ...

Example Embodiment

[0035] Example 2 Preparation of traditional Chinese medicine biological preparation of the present invention

[0036] Chinese medicine composition: 70 parts of Eucommia leaves, 60 parts of Grifola frondosa, 40 parts of Astragalus, 30 parts of Epimedium Preparation method:

[0037] (1) Inoculate Bacillus into common broth medium, culture at 36℃, 230rpm shaker to produce first-level seed liquid, when the content of viable bacteria reaches 1.0×10 8~9 When cfu / ml, transfer to the secondary seed liquid fermentor to expand the culture, the inoculum amount is 8%, the culture temperature is 29℃, the stirring speed is 230rpm, and the viable bacteria content of the secondary seed liquid reaches 1.0×10 8~9 When cfu / ml, stop the culture and reserve;

[0038] (2) Take a prescription amount of Chinese medicinal materials, crush them into 100 mesh medicinal powders, put them in a fermenter, add 15% bran, 8% soybean meal, 0.4% ammonium sulfate, 0.03% magnesium sulfate, 0.03% by weight of the Chines...

Example Embodiment

[0041] Example 3 Preparation of Traditional Chinese Medicine Biological Preparation of the Invention

[0042] Chinese medicine composition: 125 parts of Eucommia leaves, 125 parts of Grifola frondosa, 80 parts of Astragalus, 70 parts of Epimedium Preparation method:

[0043] (1) Inoculate Bacillus into common broth medium, culture at 35℃, 200rpm shaker to produce first-level seed liquid, when the content of viable bacteria reaches 1.0×10 8~9 When cfu / ml, transfer to the secondary seed liquid fermentor to expand the culture, the inoculum amount is 9%, the culture temperature is 30℃, the stirring speed is 200rpm, and the viable bacteria content of the secondary seed liquid reaches 1.0×10 8~9 When cfu / ml, stop the culture and reserve;

[0044] (2) Take the prescription amount of Chinese medicinal materials, crush them into 90 mesh medicinal powder, put them into the fermentation tank, add 25% bran, 5% soybean meal, 0.8% ammonium sulfate, 0.08% magnesium sulfate, 0.04% by weight of the ...

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Abstract

The invention relates to a traditional Chinese medicine biological agent for improving immunity of livestock and a preparation method thereof; the traditional Chinese medicine biological agent is prepared by combining traditional Chinese medicine formulas and modern microbiological technology; the biological agent adopts folium cortex eucommiae, grifola frondosa, astragalus root and herba epimedii, which belong to traditional Chinese medicines, as raw materials; bran, bean pulp, ammonium sulfate, magnesium sulfate, calcium carbonate and water are added in the raw materials after the raw materials are crushed, so as to form fermentation medium, strain nutrient solution with a certain proportion is added in the fermentation medium for fermentation, the mature solid fermentation broth is added in alcohol for extraction, separation, filtration, concentration, so as to prepare various dosage forms. The traditional Chinese medicine biological agent prepared by microbial fermentation metabolism can remarkably improve the immunity of livestock organisms, enhance the immunity of the organisms, improves the production performance of the livestock and effectively prevent immunity inhibitive diseases.

Description

technical field [0001] The invention relates to a traditional Chinese medicine biological preparation for improving the immunity of livestock and poultry and a preparation method thereof, belonging to the field of veterinary medicine. Background technique [0002] In recent years, in the production of livestock and poultry, it is common that the preventive effect of vaccination is not good, and the dosage of the drug is gradually increased, but the ideal therapeutic and preventive effect is still not achieved. This is due to a large number of abused drugs and unreasonable vaccines for a long time Inoculation leads to a decline in the immune function of livestock and poultry, especially in a depressed or suppressed state of immune cells such as lymphocytes and macrophages; in addition, new animal diseases have emerged in recent years and pathogens of old diseases have mutated and virulently increased. To solve this problem, it is necessary to take effective measures to activa...

Claims

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Application Information

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IPC IPC(8): A61K36/539A61P37/04A23K1/00C12P1/04C12R1/10C12R1/125A23K10/12A23K10/30
Inventor 黄建茹杨秀玉莫云刘钧刘澜葛冰张俊儒葛代兴田玲邓利斌丛日刚
Owner BEIJING DABEINONG ANIMAL HEALTH TECH
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