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Compound thrombus-clearing Chinese medicinal preparation and preparation method thereof

A technology of compound Xueshuantong and traditional Chinese medicine preparations, which is applied in drug combinations, medical formulas, cardiovascular diseases, etc., can solve the problems of limited dissolution of active ingredients, non-extraction of notoginseng saponins, failure to be rationally utilized, etc., to improve blood Circulation and microcirculation, good clinical efficacy, effect of improving bioavailability

Active Publication Date: 2010-06-02
GUANGDONG ZHONGSHENG PHARMA
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

The raw powder of Panax notoginseng is used as medicine, the active ingredient needs to be released through the cell wall first, and Panax notoginseng has a solid texture, known as "copper skin and iron bone", which leads to limited dissolution of active ingredients, extraction 2 to 3 times, and notoginseng saponins cannot be extracted Completely, the extracted Panax notoginseng dregs are discarded, which contains a large amount of active ingredients and cannot be rationally utilized, resulting in a large waste of resources

Method used

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  • Compound thrombus-clearing Chinese medicinal preparation and preparation method thereof
  • Compound thrombus-clearing Chinese medicinal preparation and preparation method thereof
  • Compound thrombus-clearing Chinese medicinal preparation and preparation method thereof

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Experimental program
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Effect test

Embodiment 1

[0037] 1. Study on the content determination of the components of Panax notoginseng medicinal dregs

[0038] The present invention confirms that the notoginseng drug residue still contains a large amount of active ingredients by measuring and researching the content of each component of the notoginseng drug residue, which corresponds to each chemical component of the notoginseng exerting its pharmacological effects, and illustrates that the notoginseng drug residue is used as a medicine. feasibility. List the test data of the present invention below to support:

[0039] 1. Panax notoginseng total saponins in the medicinal residues of notoginseng

[0040] The content of total saponins in Panax notoginseng was determined by vanillin-perchloric acid colorimetry, and the results are shown in Table 1. The test shows that the content of total saponins in Panax notoginseng medicinal materials is 9.81%-11.64%, and that in the medicinal residue of Panax notoginseng is 1.25%. 3.68%, i...

Embodiment 2

[0182] Compound Xueshuantong Capsules

[0183] Weigh the raw materials according to the following ratio (grams)

[0184] Panax notoginseng 500g Astragalus 160g Salvia miltiorrhiza 100g Scrophulariaceae 160g Panax notoginseng dregs powder 300-400g

[0185] The preparation method that above-mentioned medicine is made medicine of the present invention is:

[0186] (1) Panax notoginseng coarsely crushed, soaked twice with 50% ethanol, 5 days for the first time, 2 days for the second time, filtered, combined filtrate, recovered ethanol and concentrated to a relative density of 1.15-1.20 (30°C), Dried the dregs, crushed into fine powder, and sieved; (2) Astragalus, Salvia miltiorrhiza and Scrophulariaceae three herbs, added 50% ethanol and heated to reflux twice, the first time for 3 hours, the second time for 2 hours, filtered and combined The filtrate is recovered from ethanol and concentrated to a relative density of 1.15-1.20 (30°C); (3) two kinds of concentrated liquid extrac...

Embodiment 3

[0188] Compound Xueshuantong Tablets

[0189] Weigh the raw materials according to the following ratio (grams)

[0190] Panax notoginseng 500g Astragalus 160g Salvia miltiorrhiza 100g Scrophulariaceae 160g Panax notoginseng dregs powder 300-400g.

[0191] The preparation method that above-mentioned medicine is made medicine of the present invention is:

[0192] (1) Panax notoginseng coarsely crushed, soaked twice with 50% ethanol, 5 days for the first time, 2 days for the second time, filtered, combined filtrate, recovered ethanol and concentrated to a relative density of 1.15-1.20 (30°C), Dried the dregs, crushed into fine powder, and sieved; (2) Astragalus, Salvia miltiorrhiza and Scrophulariaceae three herbs, added 50% ethanol and heated to reflux twice, the first time for 3 hours, the second time for 2 hours, filtered and combined Filtrate, recovered ethanol and concentrated to a relative density of 1.15 ~ 1.20 (30 ° C); (3) the two concentrated liquid extracts, fine pow...

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Abstract

The invention discloses a compound thrombus-clearing Chinese medicinal preparation and a preparation method thereof. The compound thrombus-clearing Chinese medicinal preparation comprises active ingredients and / or pharmaceutically acceptable additives which are prepared from the following raw materials: 200 to 1,000 grams of sanchi, 50 to 400 grams of astragalus, 40 to 20 grams of radix salviae miltiorrhizae, 60 to 400 grams of figwort root, and 100 to 800 grams of sanchi decoction dreg powder. The Chinese medicinal preparation has the functions of quickening the blood and transforming stasis, expanding blood vessels, increasing blood flow volume, improving blood circulation and microcirculation and tonifying qi and yin and is mainly used for treating the symptoms of retinal vein occlusion caused by blood stasis and qi and yin deficiency, such as blurred vision or paropsis, eyeground blood stasis, fatigued spirit and lack of strength, dry throat and dry mouth. The Chinese medicinal preparation is also applicable to people with the symptoms of stable exertional angina caused by blood stasis and qi and yin deficiency, such as chest distress, chest pain, palptation, flusteredness, shortness of breath, lack of strength, heart vexation and dry mouth.

Description

technical field [0001] The invention relates to a compound Xueshuantong traditional Chinese medicine preparation and a preparation method thereof, more particularly to a traditional Chinese medicine preparation containing notoginseng dregs and a preparation method thereof; A traditional Chinese medicine preparation with better clinical efficacy for stable exertional angina pectoris caused by deficiency of both qi and yin. Background technique [0002] Panax notoginseng is the root of Araliaceae plant Panax notoginseng (Burk.) F.H.Chen. "Compendium of Materia Medica" says: "The taste is slightly sweet and bitter, resembling the taste of ginseng" and "can cure all blood diseases"; "Supplements" says: "Notoginseng nourishes the blood first", "is the most precious of traditional Chinese medicine"; Swelling, all blood stasis will be broken; all new blood will be stopped for vomiting, metrorrhagia, knife wounds, and arrows.” [0003] Radix Notoginseng has the effect of dispelli...

Claims

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Application Information

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IPC IPC(8): A61K36/808A61P9/02A61P9/10
Inventor 龙超峰谢称石
Owner GUANGDONG ZHONGSHENG PHARMA
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