Hirudin vacuum blood collection tube

A technology of vacuum blood collection tubes and hirudin, which is applied in the directions of sensors, diagnosis, packaging items, etc., can solve the problems of cumbersome use, impurities, heavy metals, and blood interference, etc., to achieve convenient operation by doctors, long anticoagulation time, Pain-reducing effect

Inactive Publication Date: 2010-07-21
刘金雪 +1
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  • Abstract
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AI Technical Summary

Problems solved by technology

[0002] At present, the vacuum blood collection tubes commonly used in clinical practice have the following defects: 1. Add different additives according to the different colors of the caps to detect different items, which is very cumbersome to use
2. Since the additives used in the tube are all chemical anticoagulants, the test results are irreversible. Once

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  • Hirudin vacuum blood collection tube

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Embodiment Construction

[0018] A hirudin vacuum blood collection tube is coated with a hirudin coating on the inner wall of the tube, and the content of the hirudin is 0.005-1 mg / ml blood volume. The amount of hirudin in the tube is 0.01 mg, and the amount of hemolysis is 2 ml; the amount of hirudin in the tube is 0.015 mg, and the amount of hemolysis is 5 ml;

[0019] The small molecular active protein in this tube has a direct inhibitory effect on thrombin in the blood, inactivating thrombin to prevent blood coagulation. There is no interference with hemoglobin, hematocrit, and white blood cells in the blood. It can replace common clinical anticoagulants: heparin (green cap), EDTA2K salt (purple cap), sodium citrate (black cap), oxalic acid, potassium oxalate (gray cap), etc. It can replace the 8 kinds of color vacuum tubes currently used in clinical practice and the trouble of ordering blood collection. It is suitable for multiple inspections, easy to use, convenient for doctors to operate, and ...

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Abstract

The invention discloses a hirudin vacuum blood collection tube. A hirudin coating is coated on the inner wall of a tube body, wherein the hirudin content is 0.005 to 1 milligram per milliliter of blood. The tube has the advantages that: 1, the tube can replace an anticoagulant commonly used in clinic, save the trouble of ordering in blood collection, apply to various kinds of examination, facilitate the operation of doctors and relive pains in patients; 2, as the hirudin used in the tube is a biological reagent, so the examination result is reversible and once the clinic examination fails, examination can be performed again directly without drawing block again for test; 3, the anticoagulation time is as long as more than 7 days; 4, the interference with blood is zero so as not to cause hemolytic reaction; 5, impurities and heavy metals are avoided; 6, more than 300 examination items can be performed; and 7, the biological reagent is environmental-pollution free.

Description

Technical field: [0001] The invention belongs to a disposable medical testing device, in particular to a vacuum blood collection tube with hirudin as an anticoagulant. Background technique: [0002] Vacuum blood collection tubes commonly used in clinical practice have the following defects: 1. Different additives are added according to the different colors of the caps to detect different items, which is very cumbersome to use. For example: blood collection tubes with light blue caps are clinically used for blood coagulation tests, PT, APTT, coagulation factor tests, the additive in the tube is 3.2% sodium citrate and the blood sample ratio is 1:9; blood collection tubes with green caps are clinically used For rapid plasma biochemical blood rheology test, the additives are heparin lithium and heparin sodium; the blood collection tube with purple cap is clinically used for hematology routine, whole blood test, blood rheology test, the additive is K 2 EDTA; Blood collection tu...

Claims

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Application Information

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IPC IPC(8): A61B5/154A61J1/05
Inventor 刘金雪刘晨
Owner 刘金雪
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