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Oral calcium pharmaceutical composition

A composition and drug technology, applied in the direction of drug combination, active ingredient of boron compound, pharmaceutical formula, etc.

Active Publication Date: 2010-08-11
SANSURE BIOTECH INC
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

At present, there is no related product on the market that can efficiently supplement calcium and other essential trace elements at the same time

Method used

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Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0033] Example 1: Calcium Carbonate Solid Dosage Form with Transport Substance and Its Preparation

[0034] Formula: Calcium Carbonate 1.25g, Vitamin D 2.8mg (100,000I.U. / g), Copper Oxide 1.2mg, Magnesium Oxide 65.1mg, Manganese Sulfate 5.4mg, Sodium Borate 2.0mg with 10 crystal water, Oxide Zinc 8.1 mg, 5-(2-hydroxy-4-isopropylbenzamido) pentanoic acid 90 mg, appropriate amount of starch, pharmaceutical grade maltodextrin and magnesium stearate.

[0035] Preparation: crush 1.25 grams of calcium carbonate, pass through an 80-mesh sieve, add 2.8 mg of vitamin D; 1.2 mg of copper oxide, 65.1 mg of magnesium oxide, 5.4 mg of manganese sulfate, 2.0 mg of sodium borate with 10 crystal water, 8.1 mg of oxide Zinc, 90 mg of 5-(2-hydroxy-4-isopropylbenzamido) pentanoic acid, add appropriate amount of starch, pharmaceutical grade maltodextrin and sucrose powder, use 75% ethanol as binder, granulate, dry, After adding an appropriate amount of magnesium stearate, the tablet is obtained....

Embodiment 2

[0036] Example 2: Solid calcium lactate dosage form with transport substance and its preparation

[0037] Except replacing calcium carbonate with calcium lactate, all the other all compositions and content are identical with embodiment 1. Calcium lactate was used in an amount of 3.0 grams, and the final mixture was compressed to the desired dosage form.

Embodiment 3

[0038] Example 3: Solid calcium phosphate dosage form with transport substance and its preparation

[0039] Except replacing calcium carbonate with calcium phosphate, all the other ingredients and contents are the same as in Example 1. Calcium phosphate was used in an amount of 1.29 g. The final mixture was compressed into the desired dosage form.

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PUM

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Abstract

The invention relates to an oral calcium pharmaceutical composition, which is a preparation prepared by taking calcium salt, vitamin D, boron compounds, copper compounds, magnesium compounds, manganese compounds, zinc compounds and at least one transfer substance capable of promoting calcium and mineral matter absorption of human body as active ingredients, and mixing with pharmaceutically-accepted auxiliary materials or subsidiary components. The oral calcium pharmaceutical composition can effectively supplement various trace elements necessary for human body such as calcium, copper, zinc, magnesium, manganese, boron and the like at the same time, and is used for preventing or curing diseases like osteoporosis.

Description

technical field [0001] The invention relates to an oral calcium pharmaceutical composition ， Specifically, it relates to an oral calcium pharmaceutical composition composed of calcium salt, vitamin D, trace minerals and at least one compound capable of promoting the absorption of calcium and minerals. Background technique [0002] Mixtures of vitamins and minerals are often used as adjuvant medicine for certain diseases or as a general nutritional supplement. Adequate calcium and trace mineral supplementation is important for adults and growing children. Adults, especially, need calcium supplements as they age to help prevent bone loss. For postmenopausal women, due to the reduction of estrogen, the rate of decline in bone density is faster than that of men, and the rate of loss of bone density is almost three times that of men. This means that after entering middle age, especially women, it is very likely that osteoporosis or even fractures will occur earlier, which will...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): A61K45/00A61K33/34A61P3/02A61P19/10A61K33/32A61K33/30A61K33/22A61K33/10A61K33/06A61K31/59
Inventor 邢东霞戴立忠
Owner SANSURE BIOTECH INC
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