Method for preparing taxifolin from fruit of princesplume ladysthumb

Abstract

The invention belongs to the traditional Chinese medicine field and provides a method for preparing taxifolin from fruit of princesplume ladysthumb. The method concretely includes that: dilute alcohol crushing extraction is adopted, extract is subject to centrifugation and then is put on chromatographic column, firstly water is used for washing impurities away, then ethanol is used for eluting, eluent is destained by active carbon, destaining solution is put on chromatographic column again, chloroform-ethanol is used for eluting, reduced pressure concentration, recrystallization and drying are carried out, and clear crystal is obtained. The invention has the characteristics that crushing extraction is adopted, speed is fast, the process is safe, and a lot of time can be saved.

Description

Technical field:

[0001] The invention relates to the technical field of traditional Chinese medicine, and relates to a method for preparing taxifolin from Saffron chinensis. Background technique:

[0002] Taxifolin, also known as luteolin and toxin, is a dihydroflavonoid compound with a chemical name of 5,7,3',4'-tetrahydroxydihydroflavonol.

[0003] Molecular formula: C 15 h 12 o 7 ;Molecular weight: 304.25;

[0004]

[0005] Molecular Structure:

[0006] Physical and chemical properties: It is a colorless needle-like crystal, with a melting point of 208-210°C. Soluble in ethanol, acetic acid, boiling water, slightly soluble in cold water, almost insoluble in benzene.

[0007] The traditional Chinese medicine Shuihonghuazi is the dried and mature fruit of Polygonum orentale L., a plant of the Polygonaceae family. It mainly contains flavonoids. No need, epigastric pain.

[0008] Taxifolin can affect lipid metabolism by regulating the activity of enzymes; it can in...

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