Process for preparing temperature-resistant enteric coated enzyme preparation product

A mannanase, enteric coating technology, applied in the application, animal feed, animal feed and other directions, can solve the problems of low temperature resistance, easy to be destroyed by gastric acid, etc., and achieve the effect of wide application and good enteric coating.

Inactive Publication Date: 2013-01-02
QINGDAO GENYUAN BIOLOGICAL TECH GRP
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Problems solved by technology

[0003] Feed enzyme products generally have disadvantages such as low temperature resistance in the process of feed granulation and easy damage by gastric acid in the process of animal digestion. At present, there are a wide range of temperature-resistant enzyme products on the market, but the enteric-coated process is mainly used in pharmaceuticals. and food industry applications

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  • Process for preparing temperature-resistant enteric coated enzyme preparation product
  • Process for preparing temperature-resistant enteric coated enzyme preparation product

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Embodiment Construction

[0015] An embodiment of the preparation process of a heat-resistant enteric-coated enzyme preparation product of the present invention, the specific steps are as follows:

[0016] (1) Mix the liquid single-enzyme or compound enzyme preparation with corn starch at a ratio of 1:0.8-1.2, granulate by shaking, and then use a shot blasting machine to round it, and then dry it in a fluidized bed at low temperature to make a granular enzyme preparation .

[0017] (2) Heat-resistant coating powder for self-pharmaceutical use, the components are proportioned by weight: polyol 10%-20%, cellulose sodium 2%-5%, inorganic calcium 2%-5%, and the balance is denatured Starch; self-made enteric-coating powder, the components are proportioned by weight: sodium alginate 25%-50%, modified starch 50%-75%; Mix according to the ratio of 1:1.

[0018] (3) Dissolve the mixed coating material in pure water at a weight ratio of 2% to 8%, and use boiling fluidized bed equipment to coat and dry the prod...

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Abstract

The invention provides a process for preparing a temperature-resistant enteric coated enzyme preparation product, which is characterized by comprising the following steps of: (1) mixing liquid mannase and corn starch, polishing the mixture by using a shot blasting machine after oscillating granulation, and drying the mixture at a low temperature through fluidized bed equipment to form a granular mannan enzyme preparation; (2) preparing medicinal heat-resistant coating powder by the following components in percentage by weight: 10 to 20 percent of polyalcohol, 2 to 5 percent of sodium cellulose, 2 to 5 percent of inorganic calcium and the balance of modified starch; preparing enteric coated powder by the following components in percentage by weight: 25 to 50 percent of sodium alginate and 50 to 75 percent of modified starch; mixing the prepared heat-resistant coating powder and the prepared enteric coated powder in a ratio of 1 to 1; and (3) dissolving the mixed coating material into purified water in a ratio of 4 to 8 percent, and coating and drying the product by using boiling fluidized bed equipment to form the temperature-resistant enteric coated product. The process solves the problems of temperature resistance and acid resistance, and has the advantages of simple process, convenient operation and strong practicability.

Description

technical field [0001] The invention relates to the technical field of feed enzyme preparations, in particular to a preparation process of a temperature-resistant enteric-coated mannan enzyme preparation product. Background technique [0002] Immobilized enzymes combine soluble enzymes with insoluble solid supports or embed them in carriers by chemical or physical methods. At present, a method of immobilizing enzymes on biofilms or ultrafiltration membranes to make biofilm reactors has been newly developed, so that the enzymes are separated from the whole, but the substrates, products and effectors can enter and exit, and the production capacity has been significantly improved. After the enzyme is immobilized, it has more advantages than the water-soluble enzyme: ①The stability is greatly improved. The stability to heat, pH and organic solvents is improved, the sensitivity to inhibitors is reduced, and some enzymes even have added anti-protease properties; ②The loss of enzy...

Claims

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Application Information

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Patent Type & Authority Patents(China)
IPC IPC(8): A23K1/165
Inventor 师昆景
Owner QINGDAO GENYUAN BIOLOGICAL TECH GRP
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