Footbath effervescent tablet for improving prostatitis

A technology for prostatitis and effervescent tablets, applied to medical preparations containing active ingredients, drug delivery, plant raw materials, etc., can solve the problem of slow dissolution of active ingredients of drugs, inability to quickly and fully dissolve active ingredients, and lower bioavailability, etc. question

Inactive Publication Date: 2010-09-15
GUANGDONG JIANDA LIGHTING ELECTRICAL APPLIANCE CO LTD
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

The current commercially available medicated bath pedicure products are all powder and bagged dosage forms, which are directly pulverized from the drug, and the active ingredients of the drug are slowly dissolved, especially at the water temperature acceptable to the human body. reduced bioavailability
[0004] In order to solve the technical problem that the effective ingredients of the medicine cannot be fully dissolved at the water temperature acceptable to the human body, the patent application published as CN1947684A discloses a "Muzu effervescent tablet", which comprises 20% of the total mass -40% organic acid, 20-40% sodium bicarbonate, 0.2-2.0% surfactant and 0.1%-5% lubricant, characterized in that: the traditional Chinese medicine Muzu effervescent tablet also contains Total mass 1-10% zedoary oil, 3-10% Sophora flavescens, 5-30% sodium chloride and appropriate amount of binder
The raw materials of traditional Chinese medicine in the scheme described in the above-mentioned patent application are zedoary oil and flavescens, as can be seen from the description in the instruction manual, the raw material of flavescens is just used as medicine after being pulverized, so although it is made into an effervescent tablet, it can make the tablet It dissolves rapidly when it meets water, but the active ingredients in Sophora flavescens raw material powder still cannot be dissolved quickly and fully at the water temperature acceptable to the human body

Method used

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  • Footbath effervescent tablet for improving prostatitis
  • Footbath effervescent tablet for improving prostatitis
  • Footbath effervescent tablet for improving prostatitis

Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0045] prescription:

[0046] Raw materials: Rehmannia glutinosa 768g, Eupatorium 588g, Radix Paeoniae Rubra 588g, Rhubarb 768g, Wang Buliuxing 990g, Sophora flavescens 990g, Cortex Phellodendri 690g, Sorrel 588g, Borneol 30g;

[0047] Excipients: citric acid 600g (calculated as anhydrous matter), sodium bicarbonate 780g, polyethylene glycol 6000 120g.

[0048] Preparation method:

[0049] For the above nine raw materials, take the Chinese herb and grind it into a fine powder, and sieve it; take the borneol and grind it into the finest powder, and sieve it; add water to decoct the remaining seven herbs such as Sophora flavescens for two times, add 8 times the amount of water for the first time, and then add 8 times the amount of water for the second time Add 6 times the amount of water each time for 3 hours, combine the second decoction, filter, and concentrate the filtrate to a thick paste with a relative density of 1.25-1.30 (measured at 60°C), add 7 / 10 scallion fine powder...

Embodiment 2

[0051] prescription:

[0052] Raw materials: Rehmannia glutinosa 420g, Eupatorium 404g, Radix Paeoniae Rubra 578g, Rhubarb 948g, Wang Buliuxing 1386g, Sophora flavescens 1155g, Cortex Phellodendri 693g, Lemon 404g, Borneol 12g;

[0053] Excipients: citric acid 300g (calculated as anhydrous), fumaric acid 300g, sodium bicarbonate 480g, sodium carbonate 300g, polyethylene glycol 6000 100g, polyethylene glycol 4000 40g.

[0054] Preparation method:

[0055] For the above nine raw materials, take the Chinese herb and grind it into fine powder and sieve it; take the borneol and grind it into the finest powder and sieve it; add water to decoct the other seven herbs such as Sophora flavescens for two times, add 10 times the amount of water for the first time, and then add water for the second time. Add 10 times the amount of water each time for 3 hours, combine the second decoction, filter, and concentrate the filtrate to a thick paste with a relative density of 1.25-1.30 (measured ...

Embodiment 3

[0057] prescription:

[0058] Raw materials: Rehmannia glutinosa 420g, Eupatorium 300g, Radix Paeoniae Rubra 410g, Rhubarb 750g, Wang Buliuxing 1172g, Sophora flavescens 1406g, Cortex Phellodendri 937g, Lemongrass 586g, Borneol 19g;

[0059] Excipients: citric acid 300g (calculated as anhydrous matter), fumaric acid 300g, sodium bicarbonate 480g, sodium carbonate 300g, polyethylene glycol 6000 100g, polyethylene glycol 4000 30g, sodium lauryl sulfate 10g, manna Alcohol 100g, peppermint oil (appropriate amount).

[0060] Preparation method:

[0061] For the above nine raw materials, take the Chinese herb and grind it into a fine powder, and sieve it; take the borneol and grind it into the finest powder, and sieve it; add water to decoct the remaining seven herbs such as Sophora flavescens for two times, add 6 times the amount of water for the first time, and then add water for the second time. Add 6 times the amount of water each time for 1.5 hours, combine the second decocti...

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Abstract

The invention relates to a traditional Chinese medicine compound preparation, in particular to a footbath effervescent tablet for improving prostatitis. The footbath effervescent tablet is mainly prepared from active ingredients, effervescent excipient, and adhesive. The compound preparation is characterized in that the active ingredients consists of 5%-20% of yam rhizome powder, 0.2%-1% of borneol powder and water extracts of the following raw materials in percentage by weight: 7%-25% of prepared rehmannia root, 5%-20% of lycopus lucidus, 5%-20% of red peony root, 7%-25% of rhubard, 10%-30% of cowherb seed, 10%-30% of lightyellow sophora root, and 5%-25% of phellodendron. The nine raw materials of footbath effervescent tablet works together to treat prostatitis.

Description

field of invention [0001] The invention relates to medical preparations, in particular to a traditional Chinese medicine compound preparation. technical background [0002] The prostate is the largest accessory gonad in the male reproductive organs. The prostatic fluid it secretes is an important part of semen. The prostate, like other organs in the body, can get sick, the most common being chronic prostatitis. It is clinically found that 25% to 50% of men have suffered from this disease. At present, prostatitis can be divided into non-specific bacterial prostatitis, idiopathic bacterial prostatitis, specific prostatitis (caused by Neisseria gonorrhoeae, Mycobacterium tuberculosis, fungi, parasites, etc.), non-specific granulomatous prostatitis, Prostatitis, prostatic hyperemia and prostatic pain caused by other pathogens (such as viruses, mycoplasma, chlamydia, etc.), modern medicine has no good prevention and treatment methods to it. However, motherland medicine has ob...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): A61K36/8945A61K9/46A61P13/08A61K31/045
Inventor 方永奇方惠新王淑英刘林
Owner GUANGDONG JIANDA LIGHTING ELECTRICAL APPLIANCE CO LTD
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