Traditional Chinese medicine composition capable of reducing blood pressure and tonifying kidney and preparation method and application thereof

Abstract

The invention discloses a traditional Chinese medicine composition capable of reducing the blood pressure and tonifying the kidney and a preparation method and application thereof. The traditional Chinese medicine composition is prepared with the following raw materials in parts by weight: 30-100 parts of sticktight, 10-30 parts of radix polygoni multiflori preparata and 3-15 parts of dogwood. Inthe preparation method, the traditional Chinese medicine ratio and formula of the traditional Chinese medicine composition provided by the invention are determined based on syndrome differentiation and treatment in accordance with the theory of traditional Chinese medicine, and the results of pharmacological experiments show that the traditional Chinese medicine composition provided by the invention has a good function of reducing the blood pressure with lasting stable effect and no recurrence, improving the biochemical indicators of the blood of patients with high blood pressure, basically preventing and treating hypertensive diseases, obviously preventing the hypertension-induced nephropathy and protecting the kidney. Moreover, the dosage of the traditional Chinese medicine composition provided by the invention is small, and no adverse reaction occurs in the experiment. Therefore, the traditional Chinese medicine composition can be used for treatment of hypertensive diseases and complications of hypertensive diseases and renal diseases.

Description

technical field [0001] The invention relates to a medicine, in particular to a traditional Chinese medicine composition with antihypertensive effect and a preparation method thereof, and also relates to the application of the traditional Chinese medicine composition in antihypertensive combined kidney disease. Background technique [0002] Hypertension has become one of the main diseases that endanger human health, and the number of deaths caused by hypertensive diseases is on the rise every year, and hypertensive diseases can also cause many complications, such as hypertension can cause target organ damage. The degree of damage is closely related to the level of blood pressure, especially the kidney damage in hypertension has seriously threatened people's health. The kidney plays an important role in the onset and maintenance of hypertension, and is also one of the important target organs of hypertension. , the renal artery is directly connected to the abdominal aorta, and ...

AI Technical Summary

Problems solved by technology

[0002] Hypertension has become one of the main diseases that endanger human health, and the number of deaths caused by hypertensive diseases is on the rise every year, and hypertensive diseases can also cause many complications, such as hypertension can cause target organ damage. The degree of damage is closely related to the level of blood pressure, especially the kidney damage in hypertension has seriously threatened people's health. The kidney plays an important role in the onset and maintenance of hypertension, and is also one of the important target organs of hypertension. , the renal artery is directly connected to the abdominal aorta, and the renal blood flow accounts for 25% of the cardiac output per unit time. The strong high-pressure blood flow has a greater impact on the intrarenal arterioles. The kidney is the most obvious when sclerosis occurs. In the early stage of hypertension (I, II stage), when there is no obvious abnormality in the routine renal function, there will be changes in the function and structure of the renal arterioles and damage to the function of the glomeruli and renal tubules. , can eventually develop into chronic renal failure, and finally lead to uremia and death. Therefore, it is particularly important to actively prevent and treat hypertension in the early stage of hypertension, that is, subclinical kidney disease. Currently, there are many antihypertensive drugs for hypertension, especially Mainly chemical drugs, most of which can only temporarily dilate blood vessels, lower blood pressure, and relieve high blood pressure, and need to be taken for a long time, cannot fundamentally solve the patient's suffering, and most high blood pressure drugs can not only protect the kidneys and other organs However, due to long-term use, it can cause adverse reactions of stomach, liver and kidney damage to patients

Traditional Chinese medicine has unique advantages in the treatment of hypertension. It can not only effectively lower blood pressure, maintain it for a long time, but also has less adverse reactions and less damage to the patient's organs. However, the current traditional Chinese medicine compound has the disadvantages of large dosage and inconvenient administration. And in the prior art, there is a lack of a traditional Chinese medicine compound that can lower blood pressure and protect the kidneys. Therefore, it is of great value to develop a drug that can effectively lower blood pressure and protect the kidneys, and has less dosage and no side effects.

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