Digital coralline hydroxyapatite artificial bone scaffold and preparation method thereof

Abstract

The invention relates to a digital coralline hydroxyapatite artificial bone scaffold and a preparation method thereof. The preparation method is characterized by comprising the following steps: 1) mixing coralline hydroxyapatite artificial bone particles and poly-L-lactic acid into a base material based on the mass ratio of 3:1; and 2) carrying out thin-layer CT scanning on bone sections, forming the shape of the artificial bone scaffold by utilizing an automatic molding machine and then carrying out laser sintering on the mixed base material to obtain the digital coralline hydroxyapatite artificial bone scaffold. The invention overcomes the complicated technology for preparing micropores in a rapid forming process and the defects that the coralline hydroxyapatite artificial bone is difficult to be prepared into the bone scaffold in a specific shape according to the clinical need; and the prepared digital coralline hydroxyapatite artificial bone scaffold can fully remain the natural micropore structure and good biocompatibility of coralline hydroxyapatite (CHA), and can be prepared into various specific shapes according to the clinical need.

Description

technical field

[0001] The invention relates to a coral hydroxyapatite artificial bone support and a preparation method thereof, which can be made into a digital coral hydroxyapatite artificial bone support widely used in repair and reconstruction operations in plastic surgery, trauma orthopedics and spinal surgery. It belongs to the technical field of medical equipment. Background technique

[0002] Due to trauma, infection, bone tumors, and abnormal development of large bone defects, it is necessary to repair the defect in clinical practice, but it is a major problem that plagues clinical medicine. In the prior art, clinically used repair materials include autologous bone, allogeneic bone, tissue engineered bone, and the like. The advantage of using autologous bone is that there is no immune reaction, but there are disadvantages such as chronic pain and other complications at the bone harvesting site, and the amount of bone harvesting is limited, and its size and shape ar...