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Method for preparing Kang'ai body resistance-strengthening tablets for treating tumors

A technology for Fuzheng Tablets and tumors, which is applied in the field of preparation of Kangai Fuzheng Tablets, can solve the problems that the curative effect of Kangai Fuzheng Tablets cannot be further improved, the extraction of active ingredients is incomplete, and the waste of active ingredients is achieved, so as to achieve the protection of active ingredients and the time limit for disintegration The effect of lengthening and content increase

Active Publication Date: 2011-11-16
山东仙河药业有限公司
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

This preparation method only uses ethanol reflux to extract Ganoderma lucidum and Ligustrum lucidum, and the amount of ethanol is large, which wastes a lot of energy, and the extraction of active ingredients is not complete, which causes waste of active ingredients in the raw materials. It can be seen that this preparation method has caused Kangai The curative effect of Fuzheng Tablets cannot be further improved

Method used

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  • Method for preparing Kang'ai body resistance-strengthening tablets for treating tumors
  • Method for preparing Kang'ai body resistance-strengthening tablets for treating tumors
  • Method for preparing Kang'ai body resistance-strengthening tablets for treating tumors

Examples

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Effect test

Embodiment 1

[0036]Ganoderma lucidum is crushed into fine powder, astragalus, privet lucidum, and epimedium are crushed into coarse powder, and set aside; use 1 mass times 75% ethanol to mix with the above-mentioned ganoderma fine powder and astragalus, privet lucidum, and epimedium coarse powder, Place it airtightly for 1-2 hours, then put the medicine powder into the percolation cylinder, remove the air, add 75% ethanol to submerge the surface of the medicine powder for 3-5cm, cover it and leave it for 48 hours, then use 75% ethanol as the solvent for percolation, keep the water The flow rate of liquid is 2-3ml·min -1 ·Kg -1 , collect about 10000ml of the filtrate, reclaim ethanol under reduced pressure at 50-60°C, concentrate the filtrate to a clear paste with a relative density of 1.15 to 1.18 (measured at 50°C); Mix with the dregs after percolation, add 8 mass times of water to decoct twice, add Tween-80 (Tween-80 is 0.05% of water quality) when decocting, the first time for 2 hours,...

Embodiment 2

[0038] Ganoderma lucidum is crushed into fine powder, astragalus, privet lucidum, and epimedium are crushed into coarse powder, and set aside; use 1 mass times 65% ethanol to mix with the above-mentioned ganoderma fine powder and astragalus, privet lucidum, and epimedium coarse powder, Place it airtightly for 1-2 hours, then put the medicine powder into the percolation cylinder, remove the air, add 65% ethanol to submerge the surface of the medicine powder for 3-5cm, cover it and leave it for 48 hours, then use 65% ethanol as the solvent for percolation, keep the water The flow rate of liquid is 2-3ml·min -1 ·Kg -1 , collect about 12000ml of the filtrate, reclaim ethanol under reduced pressure at 50-60°C, concentrate the filtrate to a clear paste with a relative density of 1.15-1.20 (measured at 50°C); Mix with the dregs after percolation, add 10 mass times of water and decoct under pressure twice, add Tween-80 (Tween-80 is 0.05% of water mass) when decocting, for the first 2...

Embodiment 3

[0040] Ganoderma lucidum is crushed into fine powder, astragalus, Ligustrum lucidum, and Epimedium are crushed into coarse powder, and set aside; use 1 mass times 70% ethanol to mix with the above-mentioned fine powder of Ganoderma lucidum, astragalus, Ligustrum lucidum, and Epimedium coarse powder, Place it airtightly for 1-2 hours, then put the medicine powder into the percolation cylinder, remove the air, add 70% ethanol to submerge the surface of the medicine powder for 3-5cm, cover it for 48 hours, then use 70% ethanol as the solvent for percolation, keep the water The flow rate of liquid is 2-3ml·min -1 ·Kg -1 , collect about 11000ml of the filtrate, reclaim ethanol under reduced pressure at 50-60°C, concentrate the filtrate to a clear paste with a relative density of 1.16-1.19 (measured at 50°C); Mix with the dregs after percolation, add 8 mass times of water to decoct twice, add Tween-80 (Tween-80 is 0.05% of water quality) when decocting, the first time for 2 hours, ...

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Abstract

The invention discloses a method for preparing Kang'ai body resistance-strengthening tablets for treating tumors, which takes glossy ganoderma, astragalus, Chinese gooseberry fruit, prepared rehmannia root, glossy privet fruit, folium epimedii and pinellia tuber (processing with ginger) as raw materials. The method comprises the following steps of: pulverizing the glossy ganoderma into fine powder, pulverizing the astragalus, the glossy privet fruit and the folium epimedii into coarse powder, extracting by a percolation method, and concentrating colature to form clear paste with the relative density between 1.15 and 1.18 (which is measured at the temperature of 50 DEG C) for later use; decocting decoction dregs and the Chinese gooseberry fruit, the Chinese gooseberry fruit and the pinellia tuber (processing with ginger) which are crushed by a crusher into water twice, merging filter liquor, concentrating the filter liquor under the reduced pressure to form clear paste with the relative density between 1.15 and 1.18 (50 DEG C), and merging the two kinds of clear paste; and preparing the clear paste in a single-step granulator to form granules, and adding a disintegrating agent and a lubricating agent to obtain tablets through mixing, tabletting and coating. The method has the advantages of low production cost, short disintegration time and high active ingredient content of the prepared Kang'ai body resistance-strengthening tablets, no toxic or side effect, quick response and good treatment effect.

Description

technical field [0001] The invention relates to a preparation method of a traditional Chinese medicine tablet, in particular to a preparation method of Kangai Fuzheng Tablet for treating tumors. Background technique [0002] There are about 1.6 million new malignant tumor patients in China every year, and about 1.3 million people die of cancer every year, which has become the number one cause of death. Radiotherapy and chemotherapy are one of the main means of treating tumors, but the side effects are very obvious, especially the inhibition of the bone marrow hematopoietic function of the body, resulting in a decrease in blood cells. Many patients cannot complete the treatment due to low white blood cells. Traditional Chinese medicine believes that the formation of tumors is the disorder of cell growth and apoptosis, cycle disorder, mainly due to stagnation of qi, blood stasis, phlegm coagulation, and accumulation of toxins, which lead to the occurrence of tumors. One of Da...

Claims

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Application Information

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Patent Type & Authority Patents(China)
IPC IPC(8): A61K36/8888A61K9/20A61P35/00
Inventor 马全龙李鹏李菁吕红叶许东升丁清波徐静刘丽赵珂陈凤雷马振霞
Owner 山东仙河药业有限公司