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Method for preparing Chinese medicinal preparation for treating influenza

A technology of influenza and traditional Chinese medicine preparations, which is applied in the field of medicine, can solve problems such as increased difficulty in post-processing, destruction of active ingredients, and potential safety hazards, so as to eliminate potential safety hazards, improve drug efficacy, and improve drug purity.

Active Publication Date: 2013-04-24
XIUZHENG PHARMA GROUP HOIDING +1
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

[0005] The purpose of the present invention is to provide a preparation method of a traditional Chinese medicine preparation for the treatment of influenza, which is used to prepare Radix Radix granules, which overcomes the high extraction temperature and long time of the existing preparation method, and the destruction of some active ingredients, which affects Drug efficacy, high impurity content, increased post-processing difficulty, potential safety hazards, environmental pollution, etc.

Method used

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  • Method for preparing Chinese medicinal preparation for treating influenza

Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0017] ① Take 1.4 kg of Radix Radix, crush it into a 30-mesh coarse powder, add 21 kg of water, and extract it with a high-voltage pulse extraction device with a field strength of 6500V, a pulse number of 1800, a temperature of 20°C, and a processing time of 12 milliseconds;

[0018] ②Filtrate the extract in ①, fine filter the filtrate with a membrane separation device, concentrate the medicinal solution with a molecular weight cut-off of less than 10,000, and concentrate it to 50°C to measure the extract with a relative density of 1.30;

[0019] ③ Add appropriate amount of dextrin and sucrose to the extract in ②, make granules, dry, make 1000g granules, and coat to obtain the present invention.

Embodiment 2

[0021] ①Take 1.4kg of Radix isatidis, crush it into a 60-mesh coarse powder, add 11kg of water, and extract it with a high-electric pulse extraction device with a field strength of 21,000V, a pulse number of 18,000, a temperature of 21°C, and a processing time of 2 milliseconds;

[0022] ②Filtrate the extract in ①, fine filter the filtrate with a membrane separation device, concentrate the medicinal solution with a molecular weight cut-off of less than 5000, and concentrate it to 50°C to measure the extract with a relative density of 1.35;

[0023] ③Add appropriate amount of soluble starch and aspartame to the extract in ②, make granules, dry, make 600g granules, and coat to obtain the present invention.

Embodiment 3

[0025] ①Take 1.4kg of Radix Radix, crush it into a 40-mesh coarse powder, add 17kg of water, and extract it with a high-electric pulse extraction device with a field strength of 10,000V, a pulse number of 12,000, a temperature of 17°C, and a processing time of 8 milliseconds;

[0026] ②Filtrate the extract in ①, fine filter the filtrate with a membrane separation device, concentrate the medicinal solution with a molecular weight cut-off of less than 8000, and concentrate it to 50°C to measure the extract with a relative density of 1.40;

[0027] ③ Add appropriate amount of dextrin and aspartame to the extract in ②, make granules, dry, make 600g granules, and coat to obtain the present invention.

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Abstract

The invention relates to a method for preparing a Chinese medicinal preparation for treating influenza, and belongs to the field of medicaments. The method is used for preparing indigowoad root granules and overcomes the defects of high extraction temperature, long time, influenced medicinal potency, high impurity content, potential safety hazards of production, environment pollution and the likein the conventional preparation method. The method of the invention comprises the following steps of: pulverizing the indigowoad root into coarse powder, adding water, extracting by using a high-electric pulse extraction device at the room temperature, filtering extract, performing fine filtering by using a membrane separation device, concentrating to form extractum, and adding a proper amount ofauxiliary materials to obtain the Chinese medicinal preparation. The method has the advantages of extracting Chinese medicinal materials by adopting the advanced high-voltage pulse extraction technology, overcoming the defects of high extraction temperature and long time in the conventional decoction method, performing the whole extraction process at the lower temperature of below 30 DEG C, improving medicinal potency, contributing to environmental protection, along with short processing time, no damage of active ingredients, high efficiency, low energy consumption, high transfer rate, and safe production and operation.

Description

technical field [0001] The invention belongs to the technical field of medicines, and in particular relates to a preparation method of a traditional Chinese medicine preparation for treating influenza. Background technique [0002] Upper respiratory tract infection, influenza, acute tonsillitis, and mumps are common clinical diseases and frequently-occurring diseases with a high incidence rate and are easily epidemic. The clinical manifestations are fever and chills, headache, dry throat, strong fever, polydipsia, and coma , Convulsions have seriously affected people's work and life. [0003] For the treatment of the above-mentioned diseases, Western medicine mostly adopts antiviral drugs and antibiotics, which have large toxic and side effects and many adverse reactions, which seriously damage the liver and kidneys of the human body; traditional Chinese medicine uses traditional Chinese medicines with heat-clearing and detoxifying effects, which have little toxic and side e...

Claims

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Application Information

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Patent Type & Authority Patents(China)
IPC IPC(8): A61K36/315A61K36/19A61K9/16A61P11/00A61P31/16A61K125/00
Inventor 高文功高陆高红梅李君海朱丽佳付强赵源慧
Owner XIUZHENG PHARMA GROUP HOIDING