Traditional Chinese medicine composition for treating psoriasis and preparation method thereof
A psoriasis and composition technology, applied in the field of medical preparations and its preparation, can solve the problems affecting the confidence of patients in treatment, toxic and side effects, easy recurrence, etc., achieve good social value and economic benefits, less toxic and side effects, and cure short time effect
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preparation example Construction
[0057] The preparation method of the oral medicine for the treatment of psoriasis of the present invention is the preparation method of honey refining pills comprising: taking 1000g of salvia miltiorrhiza, 1000g of angelica, 1000g of eclipta, 1000g of rhizoma drynariae, 1000g of scutellaria baicalensis, 1000g of astragalus, 1000g of cortex moutan, and 1000g of Patrinia , Caulis Spatholobus 1000g, Safflower 1000g, Ligusticum Chuanxiong 1000g, Kochia chinensis 1000g, Honeysuckle 1000g, Psoralea 1000g, Centipede 100g; Take the raw materials of the above weight ratio and soak for 1 hour, and then put them in a multi-functional extraction tank The amount of water added for the first decoction is 10 times that of the medicinal materials. When the decoction is heated to 100°C, start timing, and after 2 hours of slight boiling, filter and release the medicinal liquid from the feeding port, and put it in the liquid storage tank; For the second decoction, add 10 times the amount of water...
experiment example 2
[0077] Experimental Example 2: Effects on Writhing Reaction of Mice Induced by Acetic Acid
[0078] Get 40 mice, group, administration route, time and dosage are the same as above, 1h after the last administration, ip 1% acetic acid saline 0.1ml / 10g body weight, observe and record the number of writhing times of mice in each group within 30 minutes, The results in Table 2 show that the medicine significantly reduces the writhing times caused by acetic acid and shows that the preparation of the present invention has obvious analgesic effect.
[0079] Table 2 Effect on writhing response of mice caused by acetic acid (x ± SD)
[0080]
[0081] Compared with the control group: **P<0.01
experiment example 3
[0082] Experimental example 3: antipruritic effect
[0083] 40 guinea pigs were randomly divided into 4 groups, 4 in the control group, and 5 in each of the three administration groups. Shave the dorsum of the right hind foot, on the day of the experiment, scratch the shaved place (area 1cm2.) of the dorsum of the right foot with coarse sandpaper, 30min after the last administration, start to drop 0.01% histamine phosphate 0.05ml / on the wound surface, Afterwards, increase the concentration by 0.01%, 0.02%, 0.03%, and 0.04% every 3 minutes, each time is 0.05ml / only, until the guinea pig turns back to lick the right hind foot, and the last time the guinea pig turns back to lick the right hind foot. The total amount of histamine phosphate is the itching threshold, and the itching threshold of each group is recorded and compared: as seen from Table 3, the preparation of the present invention has the effect of improving the guinea pigs' itching threshold, and the antipruritic effec...
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