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Traditional Chinese medicine composition for treating psoriasis and preparation method thereof

A psoriasis and composition technology, applied in the field of medical preparations and its preparation, can solve the problems affecting the confidence of patients in treatment, toxic and side effects, easy recurrence, etc., achieve good social value and economic benefits, less toxic and side effects, and cure short time effect

Inactive Publication Date: 2011-04-06
韩亮
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

At present, there are many kinds of traditional Chinese medicines for the treatment of psoriasis, but they generally have the characteristics of long treatment course, slow effect, toxic side effects, recurrent attacks, and poor pertinence
Many patients have aggravated their condition due to inappropriate medication or wrong methods, which seriously affected patients' confidence in the treatment of this disease.
The above treatment options are all palliative, refractory, and easy to relapse, causing adverse psychological pressure and serious economic burden to the majority of patients, and causing patients to miss the best opportunity for treatment

Method used

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  • Traditional Chinese medicine composition for treating psoriasis and preparation method thereof
  • Traditional Chinese medicine composition for treating psoriasis and preparation method thereof
  • Traditional Chinese medicine composition for treating psoriasis and preparation method thereof

Examples

Experimental program
Comparison scheme
Effect test

preparation example Construction

[0057] The preparation method of the oral medicine for the treatment of psoriasis of the present invention is the preparation method of honey refining pills comprising: taking 1000g of salvia miltiorrhiza, 1000g of angelica, 1000g of eclipta, 1000g of rhizoma drynariae, 1000g of scutellaria baicalensis, 1000g of astragalus, 1000g of cortex moutan, and 1000g of Patrinia , Caulis Spatholobus 1000g, Safflower 1000g, Ligusticum Chuanxiong 1000g, Kochia chinensis 1000g, Honeysuckle 1000g, Psoralea 1000g, Centipede 100g; Take the raw materials of the above weight ratio and soak for 1 hour, and then put them in a multi-functional extraction tank The amount of water added for the first decoction is 10 times that of the medicinal materials. When the decoction is heated to 100°C, start timing, and after 2 hours of slight boiling, filter and release the medicinal liquid from the feeding port, and put it in the liquid storage tank; For the second decoction, add 10 times the amount of water...

experiment example 2

[0077] Experimental Example 2: Effects on Writhing Reaction of Mice Induced by Acetic Acid

[0078] Get 40 mice, group, administration route, time and dosage are the same as above, 1h after the last administration, ip 1% acetic acid saline 0.1ml / 10g body weight, observe and record the number of writhing times of mice in each group within 30 minutes, The results in Table 2 show that the medicine significantly reduces the writhing times caused by acetic acid and shows that the preparation of the present invention has obvious analgesic effect.

[0079] Table 2 Effect on writhing response of mice caused by acetic acid (x ± SD)

[0080]

[0081] Compared with the control group: **P<0.01

experiment example 3

[0082] Experimental example 3: antipruritic effect

[0083] 40 guinea pigs were randomly divided into 4 groups, 4 in the control group, and 5 in each of the three administration groups. Shave the dorsum of the right hind foot, on the day of the experiment, scratch the shaved place (area 1cm2.) of the dorsum of the right foot with coarse sandpaper, 30min after the last administration, start to drop 0.01% histamine phosphate 0.05ml / on the wound surface, Afterwards, increase the concentration by 0.01%, 0.02%, 0.03%, and 0.04% every 3 minutes, each time is 0.05ml / only, until the guinea pig turns back to lick the right hind foot, and the last time the guinea pig turns back to lick the right hind foot. The total amount of histamine phosphate is the itching threshold, and the itching threshold of each group is recorded and compared: as seen from Table 3, the preparation of the present invention has the effect of improving the guinea pigs' itching threshold, and the antipruritic effec...

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PUM

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Abstract

The invention discloses a traditional Chinese medicine composition for treating psoriasis. An oral administration medicament comprises 10-20 parts of salvia miltiorrhiza bunge, 10-20 parts of angelica sinensis, 10-20 parts of yerbadetajo herba ecliptae, 10-20 parts of rhizoma drynariae, 10-20 parts of scutellaria baicalensis, 10-20 parts of astragalus mongholicus, 10-20 parts of peony bark, 10-20 parts of patrinia, 10-20 parts of suberect spatholobus stem, 10-20 parts of safflower, 10-20 parts of szechuan lovage rhizome, 10-20 parts of fructus kochiae, 10-20 parts of honeysuckle flower, 10-20 parts of fructus psoraleae and 1-10 parts of centipede. An external applied medicament comprises 10-30 parts of radix sophorae flavescentis, 10-30 parts of lithospermum, 10-30 parts of rhizoma smilacis glabrae, 10-30 parts of common cnidium fruit, 10-30 parts of rhizoma drynariae, 10-30 parts of amur corktree bark, 10-30 parts of cortex dictamni, 10-30 parts of sophora flower, 10-30 parts of oldenlandia diffusa, 1-10 parts of zaocys dhumnades, 1-10 parts of stellera chamaejasme and 10-30 parts of sulphur. The invention has the advantages of high pertinence, blood cooling and vigoration, blood stasis elimination, less toxic or side effect, short curing time and difficult recrudescency after curing and is convenient to use.

Description

technical field [0001] The invention relates to a medical preparation containing components derived from plants, animals or minerals and a preparation method thereof, in particular to a traditional Chinese medicine composition for treating psoriasis and a preparation method thereof. Background technique [0002] Psoriasis is a common fungal skin disease, which is a frequently-occurring disease, also known as psoriasis. There is no consistent definite statement about the etiology. The disease is initially a red papule the size of a needle or a grain of rice, with a small amount of white scales on the surface. Later, the papule gradually expands and merges, becoming a small plaque the size of a fingernail, coin or palm, with clear borders and a red base, ranging from several to countless. , can become large lesions of various shapes, the lowest layer of scales is relatively firm, and a bright red smooth surface is exposed after scraping off. It often occurs on the limbs, scalp...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): A61K36/71A61K36/896A61P17/06A61K33/04A61K35/58A61K35/64A61K35/583A61K35/648
Inventor 韩亮魏洪莲
Owner 韩亮
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