Triterpenoid saponin compound as well as synthesis method and application of triterpenoid saponin
A technology of triterpene saponins and synthesis methods, applied in the direction of steroids, chemical instruments and methods, medical preparations containing active ingredients, etc., can solve the problems of low final yield, many by-products, complex synthesis, etc., and achieve structural Simple, low-cost, time-consuming results
Inactive Publication Date: 2011-06-15
WUHAN DAO YI TANG PHARMA RES INST
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Problems solved by technology
Such a structure makes the synthesis of this type of compound extremely complicated, with many by-products and low final yield, making it difficult to carry out large-scale industrial application
In addition, there is little research on the application of triterpenoid saponins in other diseases
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The invention provides a triterpenoid saponin compound, a synthesis method of the triterpenoid saponin compound and an application of the triterpenoid saponin compound in preparing medicaments for treating cancers and dementia. The triterpenoid saponin compound is shown in the following chemical general formula, wherein any two of R1, R2 and R3 are methyl, and the other one is hydrogen atom, R4 is pent-or hexa-monosaccharide, or disaccharide formed by the pent-or hexa-monosaccharide, or disaccharide formed by the pent-or hexa-monosaccharide, or glycosyl formed by aldehyde acid derivatives of the monosaccharide or the disaccharide, and R5 is hydrogen atom, or pent-or hexa-monosaccharide, or disaccharide formed by the pent-or hexa-monosaccharide, or substituent group formed by aldehyde acidderivatives of the monosaccharide or the disaccharide. The invention also provides a medicament with the functions of treating cancers and dementia.
Description
Triterpene saponin compound, its synthesis method and application thereof technical field The invention relates to a triterpene saponin compound, its synthesis method and its application in the preparation of medicines for treating cancer and dementia. Background technique Traditional Chinese medicine is the material basis and carrier of TCM disease prevention and health care, which contains rich scientific connotations and extremely high practical value. With the continuous development of human health care and the trend of traditional Chinese medicine going global, the social demand for traditional Chinese medicine resources has increased unprecedentedly, and the contradiction between supply and demand has become increasingly prominent. The rational development and protection of traditional Chinese medicine resources and the realization of sustainable utilization of traditional Chinese medicine resources have become the basic consensus of the Chinese government and the tr...
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IPC IPC(8): A61P31/08A61P35/00A61P1/16A61P11/06A61K31/704A61P31/20A61P31/06A61P25/28A61P5/16A61P19/04A61P37/02C07J63/00A61P31/00C07H15/256C07H1/00A61P37/06A61P13/12A61P9/12
Inventor 廖一帆江哲遒刘军李婧邴飞虹
Owner WUHAN DAO YI TANG PHARMA RES INST
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