Preparation method of nonanal and methyl formylcaprylate

Abstract

The invention relates to a preparation method of nonanal and methyl formylcaprylate. The method comprises the following steps: epoxidized methyl oleate is used as a raw material to react under the action of catalyst and generate nonanal and methyl formylcaprylate, wherein the reaction temperature is 40-100 DEG C, the pressure is atmospheric pressure; the mesoporous molecular sieve which is treated with 10-35% hydrogen peroxide is taken as a carrier for the catalyst, the weight ratio of tungsten used as main catalyst to the weight of the carrier is 0.005-0.1, and the weight ratio of one of titanium and molybdenum, used as cocatalyst to the weight of the carrier is 0-0.1. The invention has the following beneficial effects: by adopting the technical scheme that the reaction temperature is 40-100 DEG C, the pressure is atmospheric pressure; the mesoporous molecular sieve is taken as a carrier for the catalyst, tungsten is used as a main catalyst and titanium or molybdenum used as cocatalyst is added or not, the problem can be solved well. The preparation method provided by the invention has mild reaction conditions, low cost and higher product yield and is suitable for industrial production.

Description

technical field [0001] The invention relates to the field of fine chemicals, in particular to a method for preparing nonanal and methyl nonalate. Background technique [0002] Nonanal has another name called geranium aldehyde, and nonanal is an important organic intermediate, which can be oxidized into nonanoic acid, reduced to corresponding alcohol, and obtained nonanonitrile (Wang E.C., Lin G.J.Tetrahedron Letters.1998 , 39, 4047-4050), which can be converted into thiazoles that inhibit superoxidation (Chihiro, M.; Nagamoto, H.; Takemura, I.J.Med.Chem.1995, 38, 353-358), anti-ribonucleic acid Viral tetrazole compounds (Diana, G.D.; Cutcliffe, D.; Volkots, D.L.J.Med.Chem.1993, 36, 3240-3250), can also prepare benzamide compounds (Medwid, J.B. ; Paul, R.; Baker, J.S.J.Med.Chem.1990, 33, 1230-1241), etc., are widely used in the fields of medicine, polymer plasticizers, adhesives, catalysts and the like. In addition, because of its sharp aroma of beeswax and rose, it is a ki...

AI Technical Summary

Problems solved by technology

Find out that directly prepare nonanal and nonanalic acid methyl ester from methyl oleate by previous literature and laboratory result often can cause product over-oxidation and most obtain nonanalic acid and hydrogen azelate methyl ester, and the yield of nonanal is relatively low. Low