Oral Chinese medicine preparation for treating chronic periodontitis and preparation method thereof
A technology of chronic periodontitis and traditional Chinese medicine preparations, applied in the field of medical preparations, can solve the problems of high incidence, serious consequences, and difficult treatment, and achieve the effect of high incidence, poor curative effect, and long course of treatment
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preparation example Construction
[0040]The preparation method of the spray of the present invention comprises: 1000g of the raw material medicine Radix Paeoniae Rubra, 1000g of Qingdai, 1000g of Salvia Miltiorrhiza, 1000g of Rhizoma Drynariae, 1000g of Radix Notoginseng, 1000g of Angelica dahurica, 1000g of notopterygium, 1000g of Miltonia Spatholobus, 1000g of Honeysuckle, 1000g of Dandelion, Scutellaria baicalensis 1000g, Phellodendron 1000g, borneol 1000g, Eclipta 1000g, add 5-7 times the amount of water to soak for 30-45 minutes, heat and boil for 30-40 minutes, filter, and the filtrate is set aside; add 5-7 times the amount of water to the filter residue Heating for the second time, boiling for 30-40 minutes, filtering, and the filtrate for later use; adding 5-10 times the amount of water to the filter residue, heating and boiling for the third time for 40-50 minutes, and filtering; combining the three decoctions, concentrating to a relative density of The concentrated solution of 1.08; after filtering an...
experiment example 3
[0055] Experimental example 3: Cumulative toxicity test:
[0056] Chinese medicine buccal preparation of the present invention is to mice by 7.69, 19.18 and 43.21g crude drug / kg continuous medication 15 weeks (1.0ml / 100g body weight, every day 2 times) and after drug withdrawal 3 weeks, the result shows: Chinese medicine preparation of the present invention is to mice The hair, behavior, defecation, body weight, organ weight, hemogram, liver and kidney function, blood sugar, blood lipid and other indicators of the rats had no significant impact, and no abnormal changes were found in the organs with the naked eye. After taking the medicine for 3 weeks, there was no obvious change in the organs of the rats. It shows that the oral capsule of the traditional Chinese medicine preparation of the present invention has little toxicity to rats after long-term administration, and there is no abnormal reaction after drug withdrawal, so the application is safe.
specific Embodiment 1
[0099] Specific embodiment 1, Feng, man, 40 years old, recurrent gingival inflammation, pain, hemorrhage when brushing teeth, seek medical advice, check and see gingival swelling, be purple, touch easy bleeding, tenderness is obvious. Diagnosis: chronic periodontitis. Once used a variety of drugs to gargle with no obvious effect. Recipe: Radix Paeoniae Rubra 10g, Qingdai 10g, Salvia Miltiorrhiza 15g, Rhizoma Drynariae 15g, Panax notoginseng 15g, Angelica dahurica 10g, Notopterygium 10g, Caulis Spatholobus 10g, Honeysuckle 15g, Dandelion 15g, Scutellaria baicalensis 15g, Phellodendron 10g, Borneol 10g, Mohan 10g of lotus root was made into buccal solution, and the buccal solution was rinsed for three days (gargle four times a day, 10ml each time, gargle for 3 minutes and spit it out). The swelling of the gums obviously subsided, and the bleeding when brushing teeth decreased. Gargle with oral liquid for 5 days, the gums do not bleed when brushing teeth consciously, the gums do...
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