Oral Chinese medicine preparation for treating chronic periodontitis and preparation method thereof

A technology of chronic periodontitis and traditional Chinese medicine preparations, applied in the field of medical preparations, can solve the problems of high incidence, serious consequences, and difficult treatment, and achieve the effect of high incidence, poor curative effect, and long course of treatment

Inactive Publication Date: 2011-07-27
CHANGSHU HUAGANG PHARMA
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

Mechanical methods to remove plaque and calculus have high morbidity, long course of treatment, poor curative effect and serious consequences
Treatment is tricky, and most people c

Method used

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  • Oral Chinese medicine preparation for treating chronic periodontitis and preparation method thereof
  • Oral Chinese medicine preparation for treating chronic periodontitis and preparation method thereof
  • Oral Chinese medicine preparation for treating chronic periodontitis and preparation method thereof

Examples

Experimental program
Comparison scheme
Effect test

preparation example Construction

[0040]The preparation method of the spray of the present invention comprises: 1000g of the raw material medicine Radix Paeoniae Rubra, 1000g of Qingdai, 1000g of Salvia Miltiorrhiza, 1000g of Rhizoma Drynariae, 1000g of Radix Notoginseng, 1000g of Angelica dahurica, 1000g of notopterygium, 1000g of Miltonia Spatholobus, 1000g of Honeysuckle, 1000g of Dandelion, Scutellaria baicalensis 1000g, Phellodendron 1000g, borneol 1000g, Eclipta 1000g, add 5-7 times the amount of water to soak for 30-45 minutes, heat and boil for 30-40 minutes, filter, and the filtrate is set aside; add 5-7 times the amount of water to the filter residue Heating for the second time, boiling for 30-40 minutes, filtering, and the filtrate for later use; adding 5-10 times the amount of water to the filter residue, heating and boiling for the third time for 40-50 minutes, and filtering; combining the three decoctions, concentrating to a relative density of The concentrated solution of 1.08; after filtering an...

experiment example 3

[0055] Experimental example 3: Cumulative toxicity test:

[0056] Chinese medicine buccal preparation of the present invention is to mice by 7.69, 19.18 and 43.21g crude drug / kg continuous medication 15 weeks (1.0ml / 100g body weight, every day 2 times) and after drug withdrawal 3 weeks, the result shows: Chinese medicine preparation of the present invention is to mice The hair, behavior, defecation, body weight, organ weight, hemogram, liver and kidney function, blood sugar, blood lipid and other indicators of the rats had no significant impact, and no abnormal changes were found in the organs with the naked eye. After taking the medicine for 3 weeks, there was no obvious change in the organs of the rats. It shows that the oral capsule of the traditional Chinese medicine preparation of the present invention has little toxicity to rats after long-term administration, and there is no abnormal reaction after drug withdrawal, so the application is safe.

[0057] Skin and in vivo ...

specific Embodiment 1

[0099] Specific embodiment 1, Feng, man, 40 years old, recurrent gingival inflammation, pain, hemorrhage when brushing teeth, seek medical advice, check and see gingival swelling, be purple, touch easy bleeding, tenderness is obvious. Diagnosis: chronic periodontitis. Once used a variety of drugs to gargle with no obvious effect. Recipe: Radix Paeoniae Rubra 10g, Qingdai 10g, Salvia Miltiorrhiza 15g, Rhizoma Drynariae 15g, Panax notoginseng 15g, Angelica dahurica 10g, Notopterygium 10g, Caulis Spatholobus 10g, Honeysuckle 15g, Dandelion 15g, Scutellaria baicalensis 15g, Phellodendron 10g, Borneol 10g, Mohan 10g of lotus root was made into buccal solution, and the buccal solution was rinsed for three days (gargle four times a day, 10ml each time, gargle for 3 minutes and spit it out). The swelling of the gums obviously subsided, and the bleeding when brushing teeth decreased. Gargle with oral liquid for 5 days, the gums do not bleed when brushing teeth consciously, the gums do...

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Abstract

The invention provides an oral Chinese medicine preparation for treating chronic periodontitis, which comprises the following raw medicines in parts by weight: 10-20 parts of red paeony root, 10-20 parts of indigo naturalis, 10-20 parts of Danshen roots, 10-20 parts of drynaria rhizome, 10-20 parts of pseudo-ginseng, 10-20 parts of angelica roots, 10-20 parts of notopterygium roots, 10-20 parts of suberect spatholobus stem, 10-20 parts of honeysuckle, 10-20 parts of dandelion, 10-20 parts of baical skullcap roots, 10-20 parts of golden cypress, 10-20 parts of borneol and 10-20 parts of eclipta. The oral Chinese medicine preparation has the greatest characteristic of rapidly relieving pains, can take the action of auxiliary treatment on patients subjected to dental operations, has the functions of clearing heat and detoxicating, reducing swellings and relieving the pains, removing erosion and generating muscles as well as astringing and arresting bleeding and has a good treatment effect on the periodontitis.

Description

technical field [0001] The invention relates to a medical preparation containing components derived from plants, animals or minerals, in particular to an oral traditional Chinese medicine preparation for treating chronic periodontitis and a preparation method thereof. Background technique [0002] Chronic periodontitis is also called adult periodontitis or chronic adult periodontitis. This type of periodontitis is most common in adults, but can also occur in children and adolescents. The disease progresses slowly, and it is often difficult to determine the normal age of onset. Most chronic periodontitis is slowly increasing, but intermittent periods of activity may also occur. The onset of this disease is slow, and the patient may have bleeding gums or bad smell in the mouth when brushing teeth or eating, but generally there is no obvious discomfort and is not taken seriously. Generally, with the prolongation of the course of the disease and the growth of age, the disease...

Claims

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Application Information

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IPC IPC(8): A61K36/756A61P1/02A61K31/045
Inventor 王磊张梅王宝星徐建光
Owner CHANGSHU HUAGANG PHARMA
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