Artificial bone material having controlled calcium ion elution

A technology of artificial bone and calcium ions, applied in bone implants, medical science, prostheses, etc., can solve the problems of insufficient therapeutic effect and achieve the effect of inhibiting cytotoxicity and inflammatory response
CN102137685AInactive Publication Date: 2011-07-27NEXT21 KK
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Patent Information

Authority / Receiving Office
CN Β· China
Patent Type
Applications(China)
Current Assignee / Owner
NEXT21 KK
Publication Date
2011-07-27
Estimated Expiration
Not applicable Β· inactive patent

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Abstract

Disclosed is an artificial bone material having controlled calcium ion elution, which does not induce cytotoxicity or any inflammatory response. It is found that the elution of a calcium ion from an artificial bone material for transplantation which contains a calcium-containing substance can be prevented effectively by subjecting the carrier to a surface treatment or adding a surface-treating agent to the carrier. It is also found that the induction of cytotoxicity can be prevented and the induction of an inflammatory response can also be prevented by using the above-mentioned carrier having controlled calcium ion elution.
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Description

technical field

[0001] The present invention relates to a medical artificial bone material (artificial bone material capable of controlling calcium ion precipitation) implanted in a living body. Background technique

[0002] In the prior art, artificial bone materials are implanted in the human body for the purpose of treatment, and calcium-containing substances are widely used as such artificial bone materials. For example, Japanese Patent Laid-Open Publication No. 2006-346159 discloses a living tissue filling material, and calcium phosphate is used to manufacture the porous living tissue filling material.

[0003] In addition, Japanese Patent Laid-Open Publication No. 2002-248119 discloses an artificial vertebral body containing hydroxyapatite and collagen. An artificial organ implant containing calcium phosphate is disclosed in WO2005 / 032456.

[0004] Calcium-containing substances are widely used as biomaterials, but there is a problem that sufficient therapeutic effect...

Claims

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