Cosmetic composition

Abstract

The invention relates to a cosmetic composition, in particular to a cosmetic composition containing phospholipid hydroperoxide glutathione peroxidase and reduced glutathione, which is characterized by consisting of 0.01%-1% of phospholipid hydroperoxide glutathione peroxidase, 0.1%-5% of reduced glutathione, 5%-20% of emollient, 70%-90% of polar solvent, 0.1%-2.5% of thickener and 0.1%-5% of surfactant. The cosmetic composition is a cosmetic which is prepared by adopting a mixture of the phospholipid hydroperoxide glutathione peroxidase and the reduced glutathione, thus significantly improving the capabilities of the reduced glutathione of resisting to oxidation and scavenging free radicals.

Description

technical field [0001] The invention belongs to the technical field of cosmetics, in particular to a cosmetic composition containing phospholipid hydrogen glutathione peroxidase and reduced glutathione. Background technique [0002] Reactive oxygen species (Reactive Oxygen Species, ROS) is a very active oxygen-containing active species, ROS mainly contains oxygen free radicals (hydroxyl radicals, superoxide anion radicals) and molecular substances (hydrogen peroxide, lipid peroxidation objects) [1]. The main active oxygen radicals in organisms are singlet oxygen (102); hydrogen peroxide (H2O2), superoxide anion (O2·-), hydroxyl radical (OH·) and lipid peroxides (ROOH and ROO· ) and alkyl radicals (R·), etc., these active oxygen radicals are some highly active groups, which are easy to gain and lose electrons. Their chemical properties are very active and their oxidation ability is very strong. The harm of reactive oxygen species to cells is mainly manifested in the follow...

AI Technical Summary

Problems solved by technology

The harm of reactive oxygen species to cells is mainly manifested in the following three aspects: (1) It causes the peroxidation of unsaturated fatty acids, especially lipids with important physiological significance on biological membranes. Lipid peroxidation can directly destroy cell membranes, and in severe cases can Cause cell necrosis and apoptosis; (2) Active oxygen can attack DNA, which will cause DNA base denaturation, biological variation, metabolic disorder, and the possibility of carcinogenesis; (3) Cause amino acids in active parts of proteins and other parts Residues, such as the oxidation of amino acids such as Cys, Tyr, His, and Met, and the breaking of peptide bonds, etc., which in turn lead to changes in the high-level structure of the protein, and eventually cause protein denaturation and inactivation

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