Multilayer co-extrusion cell culture container bag packaging film

Abstract

The invention discloses a multilayer co-extrusion cell culture container bag packaging film, which comprises an upper surface layer, a middle layer and a lower surface layer which are sequentially arranged, wherein the upper surface layer, the middle layer and the lower surface layer are modified ethylene-vinyl acetate copolymer layers; the thickness of the upper surface layer is 25 to 35 percent of the total thickness of the film; the thickness of the middle layer is 35 to 45 percent of the total thickness of the film; and the thickness of the lower surface layer is 25 to 35 percent of the total thickness of the film. The multilayer co-extrusion cell culture container bag packaging film is a multilayer co-extrusion packaging film which has a high comprehensive property, particularly a high barrier property and a high sealing property which is suitable for multiple kinds of equipment and various interfaces, and has an extremely high protection property for culture of cellular fluid.

Description

technical field [0001] The invention relates to a film for biomedicine made of polymer material, more specifically, relates to a multi-layer co-extruded cell culture container bag packaging film used as a cell culture container in the field of biomedicine. Background technique [0002] At present, many domestic enterprises have developed a disposable cell culture bag (torrent bioreactor) by using a new type of oxygen transfer mechanism without bubbling. It uses a torrent oscillator to mechanically shake to generate a torrent so that the culture medium repeatedly flushes the cell culture bag. The oxygen molecular layer on the surface, and then the oxygen molecular layer can be quickly dissolved in the culture medium to meet the needs of normal cell growth and metabolism. Due to the long cycle of cell culture and high requirements on hygienic performance, it is very easy to appear in the production of disposable cell culture bag membranes by domestic conventional methods: afte...

AI Technical Summary

Problems solved by technology

Due to the long cycle of cell culture and high requirements on hygienic performance, it is very easy to appear in the production of disposable cell culture bag membranes by domestic conventional methods: after one cycle of cell culture, the selection of resin in film production is not rigorous enough, resulting in low The precipitation of molecular substances affects the culture effect of cells; the leakage of cell fluid caused by poor heat sealing strength; poor flexibility and transparency; poor welding adaptability; poor barrier properties, etc.

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