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Application of traditional Chinese medicine composition in preparing medicaments treating pancreatitis and/or cholecystitis

A composition and technology of traditional Chinese medicine, applied in the field of preparation of drugs for the treatment of pancreatitis and/or cholecystitis, can solve the problems of high postoperative recurrence rate, easy recurrence, long-term medication, etc., to overcome slow curative effect and avoid side effects , improve the effect of microcirculation

Active Publication Date: 2011-11-02
吉林一正药业集团有限公司
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

At present, western medicine adopts conservative treatment of western medicine or surgical resection for such diseases. The conservative treatment of western medicine mostly uses antibiotics. It is the main means of treating such diseases today, but this method brings more trouble and pain to patients, and is not easy to be accepted, especially the high recurrence rate and many sequelae after surgery.
Traditional Chinese medicine also has a certain therapeutic effect, but the curative effect is slow, requires long-term medication, and is prone to recurrence

Method used

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  • Application of traditional Chinese medicine composition in preparing medicaments treating pancreatitis and/or cholecystitis
  • Application of traditional Chinese medicine composition in preparing medicaments treating pancreatitis and/or cholecystitis

Examples

Experimental program
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preparation example Construction

[0027] Examples 1-8 are the preparation of pharmaceutical preparations, and Examples 9-10 are the summary of clinical experiments.

[0028] preparation of pharmaceutical preparations

Embodiment 1

[0029] Embodiment 1, preparation Chinese medicine composition capsule

[0030] Take 100g of rhubarb, 105g of gardenia, and 95g of the three flavors of Scutellaria baicalensis, clean slices or segments, and reflux extract the above-mentioned medicinal materials with 85% ethanol aqueous solution for 3 times, and the quality of the first extraction solvent is the mass of the medicinal materials. 6 times the quality of the medicinal material, extracted for 2 hours, the quality of the second extraction solvent was 6 times the quality of the medicinal material, extracted for 2 hours, the quality of the third extraction solvent was 5 times the quality of the medicinal material, extracted for 1 hour, each time After the extraction is complete, filter, collect the filtrate, combine the three filtrates, and reclaim ethanol, concentrate the filtrate at 70° C. into a thick paste with a relative density of 1.15 to 1.35, dry and pulverize to obtain a drug powder (through a 100-mesh sieve), a...

Embodiment 2

[0031] Embodiment 2, preparation Chinese medicine composition tablet

[0032] Take 100g rhubarb, 90g gardenia, and 80g Scutellaria baicalensis three herbs, clean slices or segments, and reflux extract the above-mentioned medicinal materials once with water. The quality of the extraction solvent is 8 times the mass of the medicinal materials. Extract for 3 hours. After the extraction is completed, filter Collect the filtrate, concentrate the filtrate at 70°C into a thick paste with a relative density of 1.15 to 1.35, dry and pulverize it to obtain a drug powder (through a 100-mesh sieve), add appropriate amount of starch and other auxiliary materials, mix well, granulate, and dry. Add magnesium stearate, mix well, and compress into tablets to obtain tablets.

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Abstract

The invention discloses a new use of a traditional Chinese medicine composition, i.e. application of the traditional Chinese medicine composition in preparing medicaments treating pancreatitis and / or cholecystitis. Wherein, the traditional Chinese medicine composition is prepared by the following raw materials by mass: 20-100 parts of rhubarb, 20-110 parts of gardenia and 10-100 parts of scutellaria. And a preparation method of the traditional Chinese medicine composition comprises the steps of: subjecting the raw materials of the composition to extraction with water or an ethanol solution, filtering the extract, collecting the filtrate, thus obtaining the composition. Clinical experiments indicate that: the traditional Chinese medicine composition of the invention has good effects in promoting blood circulation and removing blood stasis, as well as reducing swelling and easing pain; it also avoids some side effects of western medicine, and overcomes the traditional Chinese medicine defects of tardy curative effect and high recurrence rate, thus having important practical application value.

Description

technical field [0001] The invention relates to the application of a traditional Chinese medicine composition in the preparation of medicines for treating pancreatitis and / or cholecystitis. Background technique [0002] Acute and chronic pancreatitis and cholecystitis are common clinical diseases and frequently-occurring diseases. The main clinical manifestations of acute and chronic pancreatitis are: 1. Severe pain in the upper abdomen, sudden onset, knife-like or colic, persistent pain, mostly radiating to the lower back. 2. Nausea, vomiting, abdominal distension, diarrhea, jaundice, fever, shock, etc. Chronic pancreatitis is persistent damage to pancreatic tissue and function due to various reasons, characterized by permanent changes in the basic structure of the pancreas, extensive fibrosis, and often accompanied by functional defects of the pancreas even after the cause has been removed. The clinical manifestations are recurrent abdominal pain, endocrine and exocrine ...

Claims

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Application Information

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IPC IPC(8): A61K36/744A61P1/16A61P1/18
Inventor 于春江
Owner 吉林一正药业集团有限公司
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